2,3-epoxypropoxyphenol | 72077-13-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,3-epoxypropoxyphenol
• 英文别名: 2-(Oxiran-2-ylmethoxy)phenol
• CAS: 72077-13-5
• 化学式: C₉H₁₀O₃
• 分子量: 166.177
• InChiKey: ZTCRAKYLWCYMRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(2-aminoethyl)furan-2-ylcarboxamide 、 2,3-epoxypropoxyphenol 以 异丙醇 为溶剂， 反应 4.0h， 以30%的产率得到3-<<2-(2-furamido)ethyl>amino>-1-<2-(benzyloxy)phenoxy>propan-2-ol
  参考文献：
  名称：

  β-肾上腺素能阻断剂。24.杂环取代的1-（芳氧基）-3-[[[（氨基）烷基]氨基]丙烷-2-醇。

  摘要：

  描述了一系列1-（芳氧基）-3-[[（（酰胺基烷基）氨基]氨基]丙-2-醇的合成，其中芳基部分为杂环或酰胺基被杂环部分取代。静脉给予麻醉大鼠时，几种化合物比普萘洛尔更有效。与先前基于杂环基团的β受体阻滞剂以及侧链具有异丙基氨基或叔丁基氨基取代基的先前发现相反，当在麻醉的猫中进一步检查时，几种化合物被证明具有心脏选择性。讨论了该系列化合物显示的详细的构效关系。

  DOI：

  10.1021/jm00354a005

文献信息

• Certain benzodioxole, benzodioxane and benzodioxepin derivatives
  申请人：CIBA-GEIGY AG

  公开号：EP0498770A1

  公开（公告）日：1992-08-12

  The invention relates to the compounds of the formula I wherein each R independently represents hydrogen, lower alkyl, halogen, trifluoromethyl, lower alkoxy, carbocyclic or heterocyclic aryl, carbocyclic or heterocyclic aryloxy, carbocyclic or heterocyclic aryl-lower alkyloxy, carbocyclic or heterocyclic aryl-lower alkyl, C₃-C₇-cycloalkyl-lower alkyloxy, or C₃-C₇-cycloalkyloxy; n represents 1, 2, 3 or 4; m represents 0, 1 or 2; A represents a direct bond or lower alkylene; X represents oxygen or sulfur, R₁ represents hydrogen, acyl, lower alkoxycarbonyl, aminocarbonyl, mono- or di-lower alkylaminocarbonyl, lower alkenylaminocarbonyl, lower alkynylaminocarbonyl, carbocyclic or heterocyclic aryl-lower alkylaminocarbonyl, carbocyclic or heterocyclic arylaminocarbonyl, C₃-C₇-cycloalkylaminocarbonyl or C₃-C₇-cycloalkyl-lower alkylaminocarbonyl; R₂ represents lower alkyl, lower alkoxycarbonyl-lower alkyl, C₃-C₇-cycloalkyl, carbocyclic or heterocyclic aryl, carbocyclic or heterocyclic aryl-lower alkyl, C₃-C₇-cycloalkyl-lower alkyl, amino, mono- or di-lower alkylamino, lower alkenylamino, lower alkynylamino, carbocyclic or heterocyclic aryl-lower alkylamino, carbocyclic or heterocyclic arylamino, C₃-C₇-cycloalkylamino, C₃-C₇-cycloalkyl-lower alkylamino, lower alkoxycarbonyl-lower alkylamino or lower alkoxy; R₃ and R₄ independently represent hydrogen or lower alkyl; and pharmaceutically acceptable salts thereof; which are useful as 5-lipoxygenase inhibitors.

  本发明涉及式 I 的化合物 其中每个 R 独立地代表氢、低级烷基、卤素、三氟甲基、低级烷氧基、碳环或杂环芳基、碳环或杂环芳氧基、碳环或杂环芳基-低级烷氧基、碳环或杂环芳基-低级烷基、C₃-C₇-环烷基-低级烷氧基或 C₃-C₇-环烷氧基；n 代表 1、2、3 或 4； m 代表 0、1 或 2；A 代表直接键或低级亚烷基；X 代表氧或硫，R₁ 代表氢、酰基、低级烷氧基羰基、氨基羰基、单或双低级烷基氨基羰基、低级烯基氨基羰基、低级炔基氨基羰基、碳环或杂环芳基-低级烷基氨基羰基、碳环或杂环芳基氨基羰基、C₃-C₇-环烷基氨基羰基或 C₃-C₇-环烷基-低级烷基氨基羰基；R₂ 代表低级烷基、低级烷氧基羰基-低级烷基、C₃-C₇-环烷基、碳环或杂环芳基、碳环或杂环芳基-低级烷基、C₃-C₇-环烷基-低级烷基、氨基、单-或双-低级烷基氨基、低级烯基氨基、低级炔基氨基、碳环或杂环芳基-低级烷基氨基、碳环或杂环芳基氨基、C₃-C₇-环烷基氨基、C₃-C₇-环烷基-低级烷基氨基、低级烷氧基羰基-低级烷基氨基或低级烷氧基；R₃ 和 R₄ 独立地代表氢或低级烷基；以及它们的药学上可接受的盐；可用作 5-脂氧合酶抑制剂。
• PHOSPHORUS-CONTAINING BENZOXAZINE COMPOUND, PROCESS FOR PRODUCTION THEREOF, CURABLE RESIN COMPOSITION, CURED ARTICLE, AND LAMINATE PLATE
  申请人：SHOWA HIGHPOLYMER CO., LTD.

  公开号：EP2048147A1

  公开（公告）日：2009-04-15

  The present invention is directed to a compound serving as both a flame retardant and a curing agent (crosslinking agent) for curable resin, a method for producing the compound, a flame-retardant curable resin composition containing the compound, and a cured product and a laminated sheet having flame retardancy produced through curing the cured resin composition. The compound has a benzoxazine structure and a phosphine oxide structure in a molecule thereof.

  本发明涉及一种既用作阻燃剂又用作可固化树脂的固化剂（交联剂）的化合物、生产该化合物的方法、含有该化合物的阻燃性可固化树脂组合物，以及通过固化该固化树脂组合物生产的具有阻燃性的固化产品和层压板。该化合物在其分子中具有苯并恶嗪结构和氧化膦结构。
• FLAKY GRAPHITE CONTAINING BORON AND PRODUCTION METHOD THEREFOR
  申请人：Showa Denko K.K.

  公开号：EP2998271A1

  公开（公告）日：2016-03-23

  There is provided a flaky graphite containing boron, the flaky graphite containing boron having an average thickness of 100 nm or less and an average plate diameter dc of 0.01 to 100 µm. There is also provided a conductive resin composition comprising a resin component and a carbon component comprising at least the flaky graphite containing boron, wherein the content of the carbon component based on 100 parts by mass of the resin component is 5 to 4000 parts by mass. There are also provided a conductive coating material and a conductive adhesive using the conductive resin composition.

  提供了一种含硼的片状石墨，这种含硼的片状石墨的平均厚度为 100 nm 或以下，平均板直径 dc 为 0.01 至 100 µm。还提供了一种导电树脂组合物，该组合物包括树脂成分和至少由含硼片状石墨组成的碳成分，其中碳成分的含量以 100 份树脂成分的质量为基准，为 5 至 4000 份。此外，还提供了使用该导电树脂组合物的导电涂层材料和导电粘合剂。
• Composition for forming organic film
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US11042090B2

  公开（公告）日：2021-06-22

  The present invention provides a composition for forming an organic film, containing a polymer compound having one or more of repeating units shown by the general formulae (1) to (4) and an organic solvent containing one or more compounds selected from propylene glycol esters, ketones, and lactones, with a total concentration of more than 30 wt % with respect to the whole organic solvent. There can be provided a composition capable of forming an organic film that can be easily removed, together with a silicon residue modified by dry etching, in a wet manner with a removing liquid harmless to a semiconductor apparatus substrate and an organic resist underlayer film required in the patterning process, for example, an ammonia aqueous solution containing hydrogen peroxide called SC1, which is commonly used in the semiconductor manufacturing process.

  本发明提供了一种用于形成有机薄膜的组合物，该组合物含有具有通式(1)至(4)所示的一种或多种重复单元的聚合物化合物，以及一种有机溶剂，该有机溶剂含有一种或多种选自丙二醇酯、酮和内酯的化合物，相对于整个有机溶剂的总浓度超过 30 wt%。可以提供一种组合物，该组合物能够用一种对半导体设备基底和图案化工艺中所需的有机抗蚀剂底层膜无害的去除液，例如半导体制造工艺中常用的一种名为 SC1 的含有过氧化氢的氨水溶液，以湿法形成一种有机膜，该有机膜可以与通过干法蚀刻改性的硅残留物一起容易地去除。
• Flame retardant resin and flame retardant composition containing the same
  申请人：Chang Chun Plastics Co., Ltd.

  公开号：US20020032279A1

  公开（公告）日：2002-03-14

  The present invention relates to a phosphorus-containing epoxy resin, which is an epoxy resin modified with a side chain having a reactive phosphorus-containing compound. Also, the present invention relates to a flame-retardant resin composition, which comprises: (1) the phosphorus-containing epoxy resin, (2) a halogen-free hardener having a reactive hydrogen capable of reacting with the epoxy group in epoxy resin, and (3) a hardener promoter. The flame-retardant resin composition described above has improved excellent heat resistance and flame retardant property, and is especially suitable for adhesive laminates, composite materials, printed circuit boards, adhesive material for copper foils, and is suitable for IC packaging materials.

  本发明涉及一种含磷环氧树脂，它是一种用具有活性含磷化合物的侧链改性的环氧树脂。此外，本发明还涉及一种阻燃树脂组合物，它包括： (1) 含磷环氧树脂、 (2) 不含卤素的固化剂，其活性氢能与环氧树脂中的环氧基团发生反应，以及 (3) 硬化剂促进剂。 上述阻燃树脂组合物提高了优异的耐热性和阻燃性，特别适用于粘合层压板、复合材料、印刷电路板、铜箔粘合材料，也适用于集成电路包装材料。