4'-methoxy-biphenyl-4-carboxylic acid hydrazide | 63484-14-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4'-methoxy-biphenyl-4-carboxylic acid hydrazide
• 英文别名: 4'-Methoxy-biphenyl-4-carbonsaeure-hydrazid；4-(4-Methoxyphenyl)benzohydrazide
• CAS: 63484-14-0
• 化学式: C₁₄H₁₄N₂O₂
• mdl: MFCD01122235
• 分子量: 242.277
• InChiKey: GUXNRVLONIIENS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  64.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4’-甲氧基[1,1’-联苯]-4-甲酸甲酯 在 一水合肼 作用下， 生成 4'-methoxy-biphenyl-4-carboxylic acid hydrazide
  参考文献：
  名称：

  20.结核的化学疗法。第七部分 取代的苯基-和吡啶基-苯甲醛的硫代咪唑酮

  摘要：

  DOI：

  10.1039/jr9560000100

文献信息

• ANTIFUNGAL CYCLOHEXAPEPTIDES
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP1053247A1

  公开（公告）日：2000-11-22
• US6232290B1
  申请人：——

  公开号：US6232290B1

  公开（公告）日：2001-05-15
• [EN] NEW COMPOUND<br/>[FR] NOUVEAU COMPOSE
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：WO1999040108A1

  公开（公告）日：1999-08-12

  (EN) This invention relates to new polypeptide compounds represented by general formula (I), wherein R1, R2, R3 and R4 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on $g(b)-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.(FR) Cette invention concerne de nouveaux composés polypeptidiques représentés par la formule générale (I) dans laquelle R1, R2, R3 et R4 sont définis dans la description, ou bien un sel de ceux-ci, présentant des activités antimicrobiennes (notamment, des activités antifongiques), une activité inhibitrice sur la $g(b)-1,3-glucane synthase, un procédé permettant leur préparation, une composition pharmaceutique les contenant et une méthode de traitement prophylactique et/ou thérapeutique de maladie infectieuse notamment l'infection à Pneumocystis carinii (par exemple la pneumonie à Pneumocystis carinii) chez l'homme ou chez l'animal.
• [EN] CROSS-LINKABLE CHARGE TRANSPORT MATERIALS<br/>[FR] MATÉRIAUX DE TRANSPORT DE CHARGE RÉTICULABLES
  申请人：LOMOX LTD

  公开号：WO2017064490A1

  公开（公告）日：2017-04-20

  There is provided a compound of the formula wherein: A represents a phenyl group, a naphthyl group, a biphenyl group or two phenyl groups linked by a C1-C8 alkyl chain; B1 and B2 in each occurrence are independently selected side chains of the structure -(Y1)n-L-(Y2)m-X wherein: Y1 and Y2 in each occurrence are independently selected from O, C02- and CH2O; m and n in each occurrence are independently selected from 0 or 1; L in each occurrence is a C2-C14 straight chain alkyl group; and X in each occurrence is an independently selected cross linkable group; C is a side chain of the structure -(Z1)p-M-(Z2)q-E wherein: Z1 and Z2 are independently selected from O, CO2- and CH2O; p and q in each occurrence are independently selected from 0 or 1; M is a C1C14 straight chain alkyl group; and E comprises a charge transport group; D is a side chain of the structure -(W1)r-N-(W2)S-F wherein: W1 and W2 are independently selected from O, CO2- and CH2O; r and s in each occurrence are independently selected from 0 or 1; N is a C1C14 straight chain alkyl group; and F comprises a charge transport group or light emitter group; and wherein the charge transport group E does not contain a fluorene group other than those that form part of a spirobifluorenearylamine motif.
• 20. The chemotherapy of tuberculosis. Part VII. Thiosemicarbazones of substituted phenyl- and pyridyl-benzaldehydes
  作者：J. Cymerman-Craig、J. W. Loder

  DOI：10.1039/jr9560000100

  日期：——