1-(1-Dodecoxyethyl)benzotriazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: 1-(1-Dodecoxyethyl)benzotriazole
• 化学式: C₂₀H₃₃N₃O
• 分子量: 331.502
• InChiKey: HUOPTCBRFQZXAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  24
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  39.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  T406石油添加剂 在 对甲苯磺酸 作用下， 以 various solvent(s) 为溶剂， 反应 22.0h， 生成 1-(1-Dodecoxyethyl)benzotriazole
  参考文献：
  名称：

  Lewis Acid-Catalyzed Additions of (Benzotriazol-1-yl)diethoxymethane to Enol Ethers and Enamides. New Syntheses of β-Alkoxyalkanal and β-Aminoalkanal Acetals

  摘要：

  Addition of (benzotriazol-1-yl)diethoxymethane 11 to various acyclic and cyclic enol ethers and enamides produces the corresponding adducts, which were reacted with either NaAlH4 or Grignard reagents to afford acyclic acetal-ethers (18a-f), cyclic alpha-(substituted)-beta-acetals (19a-c), amino-acetals (24a,b), and 1,3-amino-ethers (25), all known but previously difficult-to-access classes of compounds.

  DOI：

  10.1021/jo9612335

文献信息

• Synthesis of novel 1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolines via benzotriazole methodology
  作者：Rodrigo Abonia、Andrea Albornoz、Braulio Insuasty、Jairo Quiroga、Herbert Meier、Angelina Hormaza、Manuel Nogueras、Adolfo Sánchez、Justo Cobo、John N Low

  DOI：10.1016/s0040-4020(01)00436-7

  日期：2001.6

  Pyrroloquinolines have been synthesized reacting 1-(benzotriazol-1(2)-ylmethyl)indolines with unactivated and electron-rich alkenes in the presence of p-toluenesulfonic acid catalyst. Mixtures of the expected diastereomers were obtained and some of them separated in their respective components. X-Ray diffraction along with two-dimensional NMR experiments was needed to assist the determination for both the structures of the precursors and products. (C) 2001 Elsevier Science Ltd. All rights reserved.