N-(2-chloro-4-fluorophenyl)-2,2,2-trifluoroacetamide | 227946-49-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2-chloro-4-fluorophenyl)-2,2,2-trifluoroacetamide
• CAS: 227946-49-8
• 化学式: C₈H₄ClF₄NO
• 分子量: 241.572
• InChiKey: BWRDLNUQULVMAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N-(2-chloro-4-fluorophenyl)-2,2,2-trifluoroacetamide 在 甲基溴化镁 、 水 、 potassium carbonate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 15.17h， 生成 2-chloro-3-cyclohex-2-en-1-yl-4-fluoroaniline
  参考文献：
  名称：

  室温下官能化苯胺和氨基取代的吡啶和吡嗪的邻位和间位放大

  摘要：

  一种实用的 邻位，间位，（或甚至邻位，邻位'）的苯胺，氨基吡啶，并在室温下aminopyrazines的trifluoroacetamides的镁化用TMPMgCl⋅LiCl或TMP进行2 Mg⋅2的LiCl。这些放大倍数与几种羰基官能度相容，并允许以令人满意的产率获得多取代的苯胺。

  DOI：

  10.1002/anie.201205465
• 作为产物：
  描述：

  2-氯-4-氟苯胺 、 三氟乙酸酐 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以95%的产率得到N-(2-chloro-4-fluorophenyl)-2,2,2-trifluoroacetamide
  参考文献：
  名称：

  室温下官能化苯胺和氨基取代的吡啶和吡嗪的邻位和间位放大

  摘要：

  一种实用的 邻位，间位，（或甚至邻位，邻位'）的苯胺，氨基吡啶，并在室温下aminopyrazines的trifluoroacetamides的镁化用TMPMgCl⋅LiCl或TMP进行2 Mg⋅2的LiCl。这些放大倍数与几种羰基官能度相容，并允许以令人满意的产率获得多取代的苯胺。

  DOI：

  10.1002/anie.201205465

文献信息

• N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：US20140315898A1

  公开（公告）日：2014-10-23

  The present invention relates to novel N-arylamide-substituted trifluoroethyl sulfide derivatives of the formula (I) in which X 1 , X 2 , X 3 , X 4 , R 1 , R 2 , R 3 , n have the meanings given in the description—to their use as acaricides and insecticides for controlling animal pests and to processes and intermediates for their preparation

  本发明涉及公式（I）中的新型N-芳酰胺取代三氟乙基硫醚衍生物，其中X1、X2、X3、X4、R1、R2、R3、n的含义如描述所示—它们作为杀螨剂和杀虫剂用于控制动物害虫，并涉及其制备的过程和中间体。
• N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides
  申请人：BAYER CROPSCIENCE AG

  公开号：US10051861B2

  公开（公告）日：2018-08-21

  The present invention relates to novel N-arylamide-substituted trifluoroethyl sulfide derivatives of the formula (I) in which X1, X2, X3, X4, R1, R2, R3, n have the meanings given in the description—to their use as acaricides and insecticides for controlling animal pests and to processes and intermediates for their preparation.

  本发明涉及式 (I) 的新型 N-芳酰胺取代的三氟乙基硫醚衍生物 其中 X1、X2、X3、X4、R1、R2、R3、n 具有说明中给出的含义--用作控制动物害虫的杀螨剂和杀虫剂，以及制备它们的工艺和中间体。
• [DE] HERBIZIDE 3-(BENZAZOL-4-YL)PYRIMIDINDION-DERIVATE<br/>[EN] HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES<br/>[FR] DERIVES DE 3-(BENZAZOL-4-YLE)DIONE DE PYRIMIDINE HERBICIDES
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：WO1999031091A1

  公开（公告）日：1999-06-24

  (DE) 3-(Benzazol-4-yl)pyrimidindion-Derivate der Formel (I) und deren Salze, wobei X = O, S; R1 = H, NH2, C1-C6-Alkyl, C1-C6-Halogenalkyl; R2 = H, Halogen, C1-C6-Alkyl, C1-C6-Halogenalkyl, C1-C6-Alkylthio, C1-C6-Alkylsulfinyl, C1-C6-Alkylsulfonyl; R3 = H, Halogen, C1-C6-Alkyl; R4 = H, Halogen; R5 = CN, Halogen, C1-C6-Alkyl, C1-C6-Halogenalkyl, C1-C6-Alkoxy, C1-C6-Halogenalkoxy; =Y- = eine Gruppe =N-N(R6)-, =C(ZR7)-N(R6)-, =C(ZR7)-O-, =C(ZR7)-S-; R6 = C1-C6-Alkyl, C1-C4-Halogenalkyl, C3-C6-Cycloalkyl, C3-C6-Alkenyl, C3-C6-Alkinyl, C1-C6-Alkyl-SO2, C1-C6-Alkyl-CO, C1-C6-Halogenalkyl-CO, C1-C6-Alkyl-CS, C1-C6-Alkoxy-CO, C1-C6-Alkoxy-CS oder gegebenenfalls substituiertes C1-C6-Alkyl; Z = chemische Bindung, O, S, -S(O)-, -SO2-, -NH-, -N(R8)-; R7, R8 = C1-C6-Alkyl, C1-C6-Halogenalkyl, Hydroxy-C1-C4-alkyl, Cyano-C1-C4-alkyl, C1-C4-Alkoxy-C1-C4-alkyl, C1-C4-Halogenalkoxy-C1-C4-alkyl, C3-C4-Alkenyloxy-C1-C4-alkyl, C3-C4-Alkinyloxy-C1-C4-alkyl, C3-C8-Cycloalkoxy-C1-C4-alkyl, Amino-C1-C4-alkyl, C1-C4-Alkylamino-C1-C4-alkyl, Di(C1-C4-alkyl)amino-C1-C4-alkyl, C1-C4-Alkylthio-C1-C4-alkyl, C1-C4-Halogenalkylthio-C1-C4-alkyl, C3-C4-Alkenylthio-C1-C4-alkyl, C3-C4-Alkinylthio-C1-C4-alkyl, C1-C4-Alkylsulfinyl-C1-C4-alkyl, C1-C4-Halogenalkylsulfinyl-C1-C4-alkyl, C3-C4-Alkenylsulfinyl-C1-C4-alkyl, C3-C4-Alkinylsulfinyl-C1-C4-alkyl, C1-C4-Alkylsulfonyl-C1-C4-alkyl, C1-C4-Halogenalkylsulfonyl-C1-C4-alkyl, C3-C4-Alkenylsulfonyl-C1-C4-alkyl, C3-C4-Alkinylsulfonyl-C1-C4-alkyl, C3-C6-Alkenyl, Cyano-C3-C6-alkenyl, C3-C6-Halogenalkenyl, C3-C6-Alkinyl, Cyano-C3-C6-alkinyl, C3-C6-Halogenalkinyl, HO-CO-C1-C4-alkyl, (C1-C4-Alkoxy)CO-C1-C4-alkyl, (C1-C4-Alkyl-)CS-C1-C4-alkyl, H2N-CO-C1-C4-alkyl, C1-C4-Alkyl-NHCO-C1-C4-alkyl, Di(C1-C4-alkyl)NCO-C1-C4-alkyl, Di(C1-C4-alkyl)phosphonyl-C1-C4-alkyl, gegebenenfalls substituiertes C3-C8-Cyclo-alkyl, C3-C8-Cycloalkyl-C1-C4-alkyl, Phenyl, Phenyl-C1-C4-alkyl, 3- bis 7-gliedriges Heterocyclyl oder Heterocyclyl-C1-C4-alkyl, wobei jeder Heterocyclyl-Ring ein CO- oder CS-Ringglied enthalten kann, oder, sofern Z = chemische Bindung, R7 auch H, OH, CN, SH, NH2, Halogen, -CH(OH)-CH2-R9, -CH(Halogen)-CH2-R9, -CH2-CH(Halogen)-R9, -CH=CH-R9 oder -CH=C(Halogen)-R9, wobei R9 = COOH, (C1-C4-Alkoxy)carbonyl, (C1-C4-Alkythio)carbonyl, CONH2, C1-C4-Alkyl-NHCO oder Di(C1-C4-alkyl)NCO, oder R7 + R8 = gegebenenfalls substituierte 1,3-Propylen- ,Tetramethylen-, Pentamethylen- oder Ethylenoxyethylen-Kette.(EN) The invention relates to 3-(benzazol-4-yl)pyrimidine-dione-derivatives of formula (I) and the salts thereof, whereby X = O, S; R1 = H, NH2, C1-C6-alkyl, C1-C6-alkyl halide; R2 = H, halogen, C1-C6-alkyl, C1-C6-alkyl halide, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl; R3 = H, halogen, C1-C6-alkyl; R4 = H, halogen; R5 = CN, halogen, C1-C6-alkyl, C1-C6-alkyl halide, C1-C6-alkoxyl, C1-C6-alkoxyl halide; =Y- = a group =N-N(R6)-, =C(ZR7)-N(R6)-, =C(ZR7)-O-, =C(ZR7)-S-; R6 = C1-C6-alkyl, C1-C4-alkyl halide, C3-C6-cycloalkyl, C3-C6-alkenyl, C3-C6-alkynyl, C1-C6-alkyl-SO2, C1-C6-alkyl-CO, C1-C6-alkyl halide-CO, C1-C6-alkyl-CS, C1-C6-alkoxyl-CO, C1-C6-alkoxyl-CS or optionally substituted C1-C6-alkyl; Z = chemical bond, O, S, -S(O)-, -SO2-, -NH-, -N(R8)-; R7, R8 = C1-C6-alkyl, C1-C6-alkyl halide, hydroxy-C1-C4-alkyl, cyano-C1-C4-alkyl, C1-C4-alkoxyl-C1-C4-alkyl, C1-C4-alkoxyl halide-C1-C4-alkyl, C3-C4-alkenyloxyl-C1-C4-alkyl, C3-C4-alkynyloxyl-C1-C4-alkyl, C3-C8-cycloalkoxyl-C1-C4-alkyl, amino-C1-C4-alkyl, C1-C4-alkylamino-C1-C4-alkyl, di(C1-C4-alkyl)amino-C1-C4-alkyl, C1-C4-alkylthio-C1-C4-alkyl, C1-C4-alkylthio halide-C1-C4-alkyl, C3-C4-alkenylthio-C1-C4-alkyl, C3-C4-alkynylthio-C1-C4-alkyl, C1-C4-alkylsulfinyl-C1-C4-alkyl, C1-C4-alkylsulfinyl halide-C1-C4-alkyl, C3-C4-alkenylsulfinyl-C1-C4-alkyl, C3-C4-alkynylsulfinyl-C1-C4-alkyl, C3-C6-alkenyl, cyano-C3-C6-alkenyl, C3-C6-alkenyl halide, C3-C6-alkynyl, cyano-C3-C6-alkynyl, C3-C6-alkynyl halide, HO-CO-C1-C4-alkyl, (C1-C4-alkoxyl)CO-C1-C4-alkyl, (C1-C4-alkyl)CS-C1-C4-alkyl, H2N-CO-C1-C4-alkyl, C1-C4-alkyl-NHCO-C1-C4-alkyl, di(C1-C4-alkyl)NCO-C1-C4-alkyl, di(C1-C4-alkyl)phosphonyl-C1-C4-alkyl, optionally substituted C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C4-alkyl, phenyl, phenyl-C1-C4-alkyl, 3- to 7-linked heterocyclyl or heterocyclyl-C1-C4-alkyl, whereby each heterocyclyl ring can contain a CO-ring link or CS-ring link, or provided that Z = chemical bond, R7 also H, OH, CN, SH, NH2, halogen, -CH(OH)-CH2-R9, -CH(halogen)-CH2-R9, -CH2-CH(halogen)-R9, -CH=CH-R9 or -CH=C(halogen)-R9, whereby R9 = COOH, (C1-C4-alkoxyl)carbonyl, (C1-C4-alkylthio)carbonyl, CONH2, C1-C4-alkyl-NHCO or di(C1-C4-alkyl)NCO, or R7 + R8 = an optionally substituted 1,3-propylene-, tetramethylene-, pentamethylene- or ethylene oxyethylene-chain.(FR) L'invention concerne des dérivés 3-(benzazol-4-yle)dione de pyrimidine de la formule (I) et leurs sels. Dans cette formule, X = O, S; R1 = H, NH2, alkyle C1-C6, halogénure d'alkyle C1-C6; R2 = H, halogène, alkyle C1-C6, halogénure d'alkyle, alkylthio C1-C6, alkylsulfinyle C1-C6, alkylsulfonyle C1-C6; R3 = H, halogène, alkyle C1-C6; R4 = H, halogène; R5 = CN, halogène, alkyle C1-C6, halogénure d'alkyle C1-C6, alcoxy C1-C6, halogénure d'alcoxy C1-C6; =Y- = un groupe =N-N(R6)-, =C(ZR7)-N(R6)-, =C(ZR7)-O-, =C(ZR7)-S-; R6 = alkyle C1-C6, halogénure d'alkyle C1-C4, cycloalkyle C3-C6, alkényle C3-C6, alkinyle C3-C6, alkyle C1-C6-SO2, alkyle C1-C6-CO, halogénure d'alkyle C1-C6-CO, alkyle C1-C6-CS, alcoxy C1-C6-CO, alcoxy C1-C6-CS ou alkyle C1-C6 éventuellement substitué; Z = liaison chimique, O, S, -S(O)-, -SO2-, -NH-, -N(R8)-; R7, R8 = alkyle C1-C6, halogénure d'alkyle C1-C6, hydroxy-alkyle C1-C4, cyano-alkyle C1-C4, alcoxy C1-C4-alkyle C1-C4, halogénure d'alcoxy C1-C4-alkyle C1-C4, alkényloxy C3-C4-alkyle C1-C4, alkinyloxy C3-C4-alkyle C1-C4, cycloalkoxy C3-C8-alkyle C1-C4, amino-alkyle C1-C4, alkylamino C1-C4-alkyle C1-C4, di(alkyle C1-C4)amino-alkyle C1-C4, alkylthio C1-C4-alkyle C1-C4, halogénure d'alkylthio C1-C4, alkénylthio C3-C4-alkyle C1-C4, alkinylthio C3-C4-alkyle C1-C4, alkylsulfinyle C1-C4-alkyle C1-C4, halogénure d'alkylsulfinyle C1-C4-alkyle C1-C4-alkénylsulfinyle C3-C4-alkyle C1-C4, alkinylsulfinyle C3-C4-alkyle C1-C4, alkylsulfonyle C1-C4-alkyle C1-C4, halogénure d'alkylsulfonyle C1-C4-alkyle C1-C4, alkénylsulfonyle C3-C4-alkyle C1-C4, alkinylsulfonyle C3-C4-alkyle C1-C4, alkényle C3-C6, cyano-alkényle C3-C6, halogénure d'alkényle C3-C6, alkinyle C3-C6, cyano-alkinyle C3-C6, halogénure d'alkinyle C3-C6, HO-CO-alkyle C1-C4, (alcoxy C1-C4)CO-alkyle C1-C4, (alkyle C1-C4)CS-alkyle C1-C4, H2N-CO-alkyle C1-C4, alkyle C1-C4-NHCO-alkyle C1-C4, di(alkyle C1-C4)NCO-alkyle C1-C4, di(alkyle C1-C4)phosphonyle-alkyle C1-C4, cycloalkyle C3-C8 éventuellement substitué, cycloalkyle C3-C8-alkyle C1-C4, phényle, phényle-alkyle C1-C4, hétérocyclyle ayant entre 3 et 7 chaînons ou hétérocyclyle-alkyle C1-C4, chaque composé hétérocyclyle pouvant contenir un chaînon cyclique CS, ou si Z = liaison chimique, R7 désigne également H, OH, CN, SH, NH2, halogène, -CH(OH)-CH2-R9, -CH(halogène)-R9, R9 = COOH, (alcoxy C1-C4)carbonyle, (alkylthio C1-C4)carbonyle, CONH2, alkyle C1-C4-NHCO ou di(alkyle C1-C4)NCO, ou R7 + R8 = chaîne de 1,3-propylène-tétraméthylène, de pentaméthylène ou d'oxyéthylène d'éthylène, éventuellement substituée.

  （DE）本发明涉及具有式（I）的3-(苯并杂环-4-基)嘧啶二酮衍生物及其盐，其中X=O，S；R₁=H，NH₂，C₁-C₆烷基，C₁-C₆卤代烷基；R₂=H，卤素，C₁-C₆烷基，C₁-C₆卤代烷基，C₁-C₆烷硫基，C₁-C₆亚磺酰基，C₁-C₆磺酰基；R₃=H，卤素，C₁-C₆烷基；R₄=H，卤素；R₅=CN，卤素，C₁-C₆烷基，C₁-C₆卤代烷基，C₁-C₆烷氧基，C₁-C₆卤代烷氧基；=Y-为=N-N(R₆)-，=C(ZR₇)-N(R₆)-，=C(ZR₇)-O-，=C(ZR₇)-S-；R₆=C₁-C₆烷基，C₁-C₄卤代烷基，C₃-C₆环烷基，C₃-C₆烯基，C₃-C₆炔基，C₁-C₆烷基-SO₂，C₁-C₆烷基-CO，C₁-C₆卤代烷基-CO，C₁-C₆烷基-CS，C₁-C₆烷氧基-CO，C₁-C₆烷氧基-CS或C₁-C₆烷基（任选取代）；Z=化学键，O，S，-S(O)-，-SO₂-，-NH-，-N(R₈)-；R₇，R₈=C₁-C₆烷基，C₁-C₆卤代烷基，羟基-C₁-C₄烷基，氰基-C₁-C₄烷基，C₁-C₄烷氧基-C₁-C₄烷基，C₁-C₄卤代烷氧基-C₁-C₄烷基，C₃-C₄烯氧基-C₁-C₄烷基，C₃-C₄炔氧基-C₁-C₄烷基，C₃-C₈环烷氧基-C₁-C₄烷基，氨基-C₁-C₄烷基，C₁-C₄烷氨基-C₁-C₄烷基，二(C₁-C₄烷基)氨基-C₁-C₄烷基，C₁-C₄烷硫基-C₁-C₄烷基，C₁-C₄卤代烷硫基-C₁-C₄烷基，C₃-C₄烯硫基-C₁-C₄烷基，C₃-C₄炔硫基-C₄烷基，C₁-C₄烷亚磺基-C₁-C₄烷基，C₁-C₄卤代烷亚磺基-C₁-C₄烷基，C₃-C₄烯亚磺基-C₁-C₄烷基，C₃-C₄炔亚磺基-C₁-C₄烷基，C₁-C₄烷磺基-C₁-C₄烷基，C₁-C₄卤代烷磺基-C₁-C₄烷基，C₃-C₄烯磺基-C₁-C₄烷基，C₃-C₄炔磺基-C₁-C₄烷基，C₃-C₆烯基，氰基-C₃-C₆烯基，C₃-C₆卤代烯基，C₃-C₆炔基，氰基-C₃-C₆炔基，C₃-C₆卤代炔基，HO-CO-C₁-C₄烷基，(C₁-C₄烷氧基)CO-C₁-C₄烷基，(C₁-C₄烷基)CS-C₁-C₄烷基，H₂N-CO-C₁-C₄烷基，C₁-十一烷基-NHCO-C₁-C₄烷基，二(C₁-C₄烷基)NCO-C₁-C₄烷基，二(C₁-C₄烷基)磷酸基-C₁-C₄烷基，C₃-C₈环烷基（任选取代），C₃-C₈环烷基-C₁-C₄烷基，苯基，苯基-C₁-C₄烷基，3-至7-员杂环基或杂环基-C₁-C₄烷基，其中每个杂环基环可含一个CO-环键或CS-环键；或者，若Z=化学键，R₇还可为H，OH，CN，SH，NH₂，卤素，-CH(OH)-CH₂-R₉，-CH(卤素)-CH₂-R₉，-CH₂-CH(卤素)-R₉，-CH=CH-R₉或-CH=C(卤素)-R₉，其中R₉=COOH，(C₁-C₄烷氧基)羰基，(C₁-C₄烷硫基)羰基，CONH₂，C₁-C₄烷基-NHCO，或二(C₁-C₄烷基)NCO；或R₇+R₈=任选取代的1,3-丙二烯基，四亚甲基，五亚甲基或氧二亚甲基链。 （EN）发明涉及式(I)的3-(苯并杂环-4-基)嘧啶二酮衍生物及其盐，其中X=O，S；R₁=H，NH₂，C₁-C₆烷基，C₁-C₆卤代烷基；R₂=H，卤素，C₁-C₆烷基，C₁-C₆卤代烷基，C₁-C₆烷硫基，C₁-C₆亚磺酰基，C₁-C₆磺酰基；R₃=H，卤素，C₁-C₆烷基；R₄=H，卤素；R₅=CN，卤素，C₁-C₆烷基，C₁-C₆卤代烷基，C₁-C₆烷氧基，C₁-C₆卤代烷氧基；=Y-为=N-N(R₆)-，=C(ZR₇)-N(R₆)-，=C(ZR₇)-O-，=C(ZR₇)-S-；R₆=C₁-C₆烷基，C₁-C₄卤代烷基，C₃-C₆环烷基，C₃-C₆烯基，C₃-C₆炔基，C₁-C₆烷基-SO₂，C₁-C₆烷基-CO，C₁-C₆卤代烷基-CO，C₁-C₆烷基-CS，C₁-C₆烷氧基-CO，C₁-C₆烷氧基-CS或C₁-C₆烷基（任选取代）；Z=化学键，O，S，-S(O)-，-SO₂-，-NH-，-N(R₈)-；R₇，R₈=C₁-C₆烷基，C₁-C₆卤代烷基，羟基-C₁-C₄烷基，氰基-C₁-C₄烷基，C₁-C₄烷氧基-C₁-C₄烷基，C₁-C₄卤代烷氧基-C₁-C₄烷基，C₃-C₄烯氧基-C₁-C₄烷基，C₃-C₄炔氧基-C₁-C₄烷基，C₃-C₈环烷氧基-C₁-C₄烷基，氨基-C₁-C₄烷基，C₁-C₄烷氨基-C₁-C₄烷基，二(C₁-C₄烷基)氨基-C₁-C₄烷基，C₁-C₄烷硫基-C₁-C⁻烷基，C₁-C₄卤代烷硫基-C₁-C₄烷基，C₃-C₄烯硫基-C₁-C₄烷基，C₃-C₄炔硫基-C₁-C₄烷基，C₁-C₄烷亚磺基-C₁-C₄烷基，C₁-C₄卤代烷亚磺基-C₁-C₄烷基，C₃-C₄烯亚磺基-C₁-C₄烷基，C₃-C₄炔亚磺基-C₁-C₄烷基，C₁-C₄烷磺基-C₁-C₄烷基，C₁-C₄卤代烷磺基-C₁-C₄烷基，C₃-C₄烯磺基-C₁-C₄烷基，C₃-C₄炔磺基-C₁-C₄烷基，C₃-C₆烯基，氰基-C₃-C₆烯基，C₃-C₆卤代烯基，C₃-C₆炔基，氰基-C₃-C₆炔基，C₃-C₆卤代炔基，HO-CO-C₁-C₄烷基，(C₁-C₄烷氧基)CO-C₁-C₄烷基，(C₁-C₄烷基)CS-C₁-C₄烷基，H₂N-CO-C₁-C₄烷基，C₁-C₄烷基-NHCO-C₁-C₄烷基，二(C₁-C₄烷基)NCO-C₁-C₄烷基，二(C₁-C₄烷基)磷酸基-C₁-C₄烷基，C₃-C₈环烷基（任选取代），C₃-C₈环烷基-C₁-C₄烷基，苯基，苯基-C₁-C₄烷基，3-至7-员杂环基或杂环基-C₁-C₄烷基，其中每个杂环基环可含一个CO-环键或CS-环键；或者，若Z=化学键，R₇还可为H，OH，CN，SH，NH₂，卤素，-CH(OH)-CH₂-R₉，-CH(卤素)-CH₂-R₉，-CH₂-CH(卤素)-R₉，-CH=CH-R₉或-CH=C(卤素)-R₉，其中R₉=COOH，(C₁-C₄烷氧基)羰基，(C₁-C₄烷硫基)羰基，CONH₂，C₁-C₄烷基-NHCO，或二(C₁-C₄烷基)NCO；或R₇+R₈=任选取代的1,3-丙二烯基，四亚甲基，五亚甲基或氧二亚甲基链。 （FR）发明涉及式(I)的3-(苯并杂环-4-基)嘧啶二酮衍生物及其盐，其中X=O，S；R₁=H，NH₂，C₁-C₆烷基，C₁-C₆卤代烷基；R₂=H，卤素，C₁-C₆烷基，C₁-C₆卤代烷基，C₁-C₆烷硫基，C₁-C₆亚磺酰基，C₁-C₆磺酰基；R₃=H，卤素，C₁-C₆烷基；R₄=H，卤素；R₅=CN，卤素，C₁-C₆烷基，C₁-C₆卤代烷基，C₁-C₆烷氧基，C₁-C₆卤代烷氧基；=Y-为=N-N(R₆)-，=C(ZR₇)-N(R₆)-，=C(ZR₇)-O-，=C(ZR₇)-S-；R₆=C₁-C₆烷基，C₁-C₄卤代烷基，C₃-C₆环烷基，C₃-C₆烯基，C₃-C₆炔基，C₁-C₆烷基-SO₂，C₁-C₆烷基-CO，C₁-C₆卤代烷基-CO，C₁-C₆烷基-CS，C₁-C₆烷氧基-CO，C₁-C₆烷氧基-CS或C₁-C₆烷基（任选取代）；Z=化学键，O，S，-S(O)-，-SO₂-，-NH-，-N(R₈)-；R₇，R₈=C₁-C₆烷基，C₁-C₆卤代烷基，羟基-C₁-C₄烷基，氰基-C₁-C₄烷基，C₁-C₄烷氧基-C₁-C₄烷基，C₁-C₄卤代烷氧基-C₁-C₄烷基，C₃-C₄烯氧基-C₁-C₄烷基，C₃-C₄炔氧基-C₁-C₄烷基，C₃-C₈环烷氧基-C₁-C₄烷基，氨基-C₁-C₄烷基，C₁-C₄烷氨基-C₁-C₄烷基，二(C₁-C₄烷基)氨基-C₁-C₄烷基，C₁-C₄烷硫基-C₁-C₄烷基，C₁-C₄卤代烷硫基-C₁-C₄烷基，C₃-C₄烯硫基-C₁-C₄烷基，C₃-C₄炔硫基-C₁-C₄烷基，C₁-C₄烷亚磺基-C₁-C₄烷基，C₁-C₄卤代烷亚磺基-C₁-C₄烷基，C₃-C₄烯亚磺基-C₁-C₄烷基，C₃-C₄炔亚磺基-C₁-C₄烷基，C₁-C₄烷磺基-C₁-C₄烷基，C₁-C₄卤代烷磺基-C₁-C₄烷基，C₃-C₄烯磺基-C₁-C₄烷基，C₃-C₄炔磺基-C₁-C₄烷基，C₃-C₆烯基，氰基-C₃-C₆烯基，C₃-C₆卤代烯基，C₃-C₆炔基，氰基-C₃-C₆炔基，C₃-C₆卤代炔基，HO-CO-C₁-C₄烷基，(C₁-C₄烷氧基)CO-C₁-C₄烷基，(C₁-C₄烷基)CS-C₁-C₄烷基，H₂N-CO-C₁-C₄烷基，C₁-C₄烷基-NHCO-C₁-C₄烷基，二(C₁-C₄烷基)NCO-C₁-C₄烷基，二(C₁-C₄烷基)磷酸基-C₁-C₄烷基，C₃-C₈环烷基（任选取代），C₃-C₈环烷基-C₁-C₄烷基，苯基，苯基-C₁-C₄烷基，3-至7-员杂环基或杂环基-C₁-C₄烷基，其中每个杂环基环可含一个CO-环键或CS-环键；或者，若Z=化学键，R₇还可为H，OH，CN，SH，NH₂，卤素，-CH(OH)-CH₂-R₉，-CH(卤素)-CH₂-R₉，-CH₂-CH(卤素)-R₉，-CH=CH-R₉或-CH=C(卤素)-R₉，其中R₉=COOH，(C₁-C₄烷氧基)羰基，(C₁-C₄烷硫基)羰基，CONH₂，C₁-C₄烷基-NHCO，或二(C₁-C₄烷基)NCO；或R₇+R₈=任选取代的1,3-丙二烯基，四亚甲基，五亚甲基或氧二亚甲基链。
• HERBIZIDE 3-(BENZAZOL-4-YL)PYRIMIDINDION-DERIVATE
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP1047693A1

  公开（公告）日：2000-11-02
• N-ARYLAMIDINE-SUBSTITUIERTE TRIFLUOROETHYLSULFID-DERIVATE ALS AKARIZIDE UND INSEKTIZIDE
  申请人：Bayer CropScience AG

  公开号：EP2793578B1

  公开（公告）日：2018-06-06