3-[(2-Hydroxy-3-phenoxypropyl)amino]propan-1-ol | 445471-65-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-[(2-Hydroxy-3-phenoxypropyl)amino]propan-1-ol
• 英文别名: 1-(3-hydroxypropylamino)-3-phenoxypropan-2-ol
• CAS: 445471-65-8
• 化学式: C₁₂H₁₉NO₃
• mdl: MFCD03034986
• 分子量: 225.28
• InChiKey: MSQWBLUPIPSXPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  61.7
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF
  申请人：VEPACHEDU SREENIVASARAO

  公开号：US20200069674A1

  公开（公告）日：2020-03-05

  Compounds of Formula I, pharmaceutically acceptable salts thereof, enantiomers thereof, metabolites thereof, derivatives thereof, prodrugs thereof, acid addition salts thereof, pharmaceutically acceptable salts thereof, or N-oxides thereof; or a combination thereof; processes and intermediates for preparation thereof, compositions thereof, and uses thereof; are provided. Pharmaceutical compositions comprising a compound of Formula I, or enantiomers thereof, metabolites thereof, derivatives thereof, prodrugs thereof, acid addition salts thereof, pharmaceutically acceptable salts thereof, or N-oxides thereof; or a combination thereof; wherein the compound is a double and/or triple agent or ligand for CYP2D6, 5-HT2A, and/or 5HT2C receptors, and/or acetylcholinesterase are provided.