7-Octadecenal | 56555-00-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-Octadecenal
• 英文别名: octadec-7-enal
• CAS: 56555-00-1
• 化学式: C₁₈H₃₄O
• 分子量: 266.5
• InChiKey: GZCDEEDYUSVIMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  19
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] CATIONIC LIPIDS<br/>[FR] LIPIDES CATIONIQUES
  申请人：UNIV EDINBURGH

  公开号：WO2009050483A1

  公开（公告）日：2009-04-23

  This invention relates to cationic lipids. More particularly the invention relates to biodegradable cationic lipids having a plurality of cationic headgroups and one or more lipophilic tail groups. The lipids are of utility in various applications, and in particular in permitting transfection of molecules, and in particular DNA and RNA, into cells. As such the lipids have specific utility in the field of gene therapy as well as other applications such as delivery of small molecules into cells, detergents, and metal ion complexation for medical or industrial applications.

  这项发明涉及阳离子脂质。更具体地，该发明涉及具有多个阳离子头基和一个或多个亲脂尾基的可生物降解阳离子脂质。这些脂质在各种应用中具有实用性，特别是在允许分子转染，特别是DNA和RNA，进入细胞方面。因此，这些脂质在基因治疗领域以及其他应用中具有特定的实用性，如将小分子输送到细胞中、洗涤剂以及医疗或工业应用中的金属离子络合。
• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• CATIONIC LIPIDS
  申请人：The University Court Of The University of Edinburgh

  公开号：EP2212279A1

  公开（公告）日：2010-08-04
• US7906147B2
  申请人：——

  公开号：US7906147B2

  公开（公告）日：2011-03-15