2-Methylcyclopentanethiol | 57067-19-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: 2-Methylcyclopentanethiol
• 英文别名: 2-methylcyclopentane-1-thiol
• CAS: 57067-19-3
• 化学式: C₆H₁₂S
• 分子量: 116.23
• InChiKey: FRXFKSPCPCSYJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME
  申请人：Mitsui Chemicals Agro, Inc.

  公开号：US20150368249A1

  公开（公告）日：2015-12-24

  Provided is a pest control agent containing a fused ring pyrimidine compound represented by the following formula (I) or a salt thereof as an effective component. In formula (I), A represents a nitrogen atom or C—R 4 , B represents a nitrogen atom or C—R 5 , D represents a nitrogen atom or C—R 6 , X represents an oxygen atom, N—R 7 or the like, each of R 1 , R 2 , R 4 and R 6 independently represents a hydrogen atom or the like, each of R 3a and R 3b independently represents a hydrogen atom or the like, R 5 represents an alkylthio group or the like, R 7 represents an alkoxy group or the like, and Ht represents a pyridyl group that may be substituted, or the like.

  提供的是一种杀虫剂，其有效成分为以下式子（I）所表示的融合环嘧啶化合物或其盐。在式（I）中，A表示氮原子或C-R4，B表示氮原子或C-R5，D表示氮原子或C-R6，X表示氧原子，N-R7或类似物，R1、R2、R4和R6中的每一个独立地表示氢原子或类似物，R3a和R3b中的每一个独立地表示氢原子或类似物，R5表示烷基硫基或类似物，R7表示烷氧基或类似物，Ht表示可能被取代的吡啶基或类似物。
• LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS
  申请人：Patil Abhimanyu O.

  公开号：US20150275117A1

  公开（公告）日：2015-10-01

  A composition containing one or more sulfur-containing compounds represented by the formula (R 1 ) a (X)(R 2 ) b wherein R 1 and R 2 are the same or different and are the residue of an olefin (e.g., aliphatic, aromatic or cycloaliphatic olefin) having from 4 to 40 carbon atoms, X is the residue of a thiol or polythiol, a is a value from 1 to 6, and b is a value from 0 to 6. The composition has a kinematic viscosity at 100° C. (Kv 100 ) from 2 to 300 cst, a kinematic viscosity at 40° C. (Kv 40 ) from 5 to 4000 cst, a viscosity index (VI) from −100 to 300, and a Noack volatility of no greater than 90 percent. A process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving one or more of solubility and dispersancy of polar additives in a lubricating oil containing the composition.

  该组成物包含一个或多个含硫化合物，其表示为(R1)a(X)(R2)b，其中R1和R2相同或不同，是具有4至40个碳原子的烯烃（例如脂肪族、芳香族或环烷烃）的残基，X是硫醇或多硫醇的残基，a的值为1至6，b的值为0至6。该组成物在100℃下的运动粘度（Kv100）为2至300 cst，在40℃下的运动粘度（Kv40）为5至4000 cst，粘度指数（VI）为-100至300，Noack挥发度不大于90％。一种生产该组成物的方法，一种润滑油基础油和含有该组成物的润滑油，以及一种用于改善润滑油中极性添加剂的溶解性和分散性的方法。
• Methods for producing members of specific binding pairs
  申请人：MEDIMMUNE LIMITED

  公开号：EP2055777A2

  公开（公告）日：2009-05-06

  A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA. Using this method libraries of DNA encoding respective chains of such multimeric sbp members may be combined, thereby obtaining a much greater genetic diversity in the sbp members than could easily be obtained by conventional methods.

  特异性结合对（sbp）的一个成员是通过在重组宿主细胞中表达编码这种 sbp 成员的遗传多样性群体的 DNA 来鉴定的，在重组宿主细胞中，sbp 成员以功能形式显示在分泌型重组基因显示包（rgdp）的表面，该包中含有编码 sbp 成员或其多肽组分的 DNA，这是因为 sbp 成员或其多肽组分是作为与 rgdp 的帽状组分融合的形式表达的。可通过与互补 sbp 成员的亲和力选择显示的 sbps，并从选定的 rgdps 中回收 DNA 以表达选定的 sbp 成员。这样就可以获得抗体 sbp 成员，并表达其不同的链，其中一条与囊膜成分融合，另一条以自由形式与融合伙伴多肽结合。噬菌体可用作表达载体，所述的噬菌体融合有助于包装噬菌体 DNA。使用这种方法可以组合编码这种多聚 sbp 成员各自链的 DNA 文库，从而获得比传统方法更容易获得的 sbp 成员遗传多样性。
• ANTI-VIRAL COMPOUNDS
  申请人：AbbVie Ireland Unlimited Company

  公开号：EP3438106A1

  公开（公告）日：2019-02-06

  This invention relates to processes and intermediates for making compounds which are effective in inhibiting replication of Hepatitis C virus (HCV).

  本发明涉及用于制造有效抑制丙型肝炎病毒（HCV）复制的化合物的工艺和中间体。
• [EN] PYRIDINE OR PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF<br/>[FR] DÉRIVÉ DE PYRIDINE OU DE PYRIMIDINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION<br/>[ZH] 吡啶或嘧啶类衍生物及其制备方法和用途
  申请人：ZHEJIANG HISUN PHARM CO LTD

  公开号：WO2021143823A1

  公开（公告）日：2021-07-22

  本发明涉及吡啶或嘧啶类衍生物、其制备方法及其在医药上的应用。具体而言，本发明涉及一种通式(I)所示的吡啶或嘧啶类衍生物、其制备方法及其可药用的盐，以及它们作为治疗剂，特别是SHP2变构抑制剂的用途，其中通式(I)中的各取代基的定义与说明书中的定义相同。