Ethanediamide, N,N'-dimethyl-N,N'-bis(1-methylethyl)- | 54965-80-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Ethanediamide, N,N'-dimethyl-N,N'-bis(1-methylethyl)-
• 英文别名: N,N'-dimethyl-N,N'-di(propan-2-yl)oxamide
• CAS: 54965-80-9
• 化学式: C₁₀H₂₀N₂O₂
• 分子量: 200.28
• InChiKey: MRFGAISYMAJLQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• IL-12 MODULATORY COMPOUNDS
  申请人：Sun Lijun

  公开号：US20100256132A1

  公开（公告）日：2010-10-07

  The invention relates to heterocyclic compounds, compositions including the compounds and methods of using and methods of making thereof. The compounds (and compositions) are useful, inter alia, in modulating IL-12 production and processes mediated by IL-12.

  本发明涉及杂环化合物、包括该化合物的组合物以及使用和制备该化合物的方法。该化合物（和组合物）在调节IL-12产生和由IL-12介导的过程中具有实用性。
• Catalyst system for enhanced stereo-specificity of olefin polymerization and method for producing olefin polymer
  申请人：Formosa Plastics Corporation, USA

  公开号：US10822438B2

  公开（公告）日：2020-11-03

  Disclosed are a catalyst component for olefin polymerization comprising titanium, magnesium, a halogen, internal donors, in combination with a silane and oxalic acid diamides of the following formula: An olefin polymerization catalyst system consisting of the solid catalyst component, an organoaluminum compound, and an optional external electron donor compound is also disclosed. Employment of both oxalic acid diamides and silane component in the presence of internal electron donors as an elements of solid Ziegler-Natta type catalyst composition enhances stereo-specificity while maintaining excellent catalyst activity and hydrogen response, in which the modified catalyst composition produces polypropylene with good productivity and higher stereo-specificity than catalyst composition without such modification.

  本发明公开了一种用于烯烃聚合的催化剂组分，该组分由钛、镁、卤素、内部供体与硅烷和下式草酸二酰胺组成： 还公开了一种烯烃聚合催化剂体系，由固体催化剂组分、有机铝化合物和任选的外部电子供体化合物组成。在内部电子供体存在的情况下，同时使用草酸二酰胺和硅烷组分作为固体齐格勒-纳塔型催化剂组合物的元素，可提高立体特异性，同时保持优异的催化剂活性和氢响应，与未进行此类改性的催化剂组合物相比，改性催化剂组合物生产的聚丙烯具有良好的生产率和更高的立体特异性。
• OXALIC ACID DIAMIDES AS MODIFIERS FOR POLYOLEFIN CATALYSTS
  申请人：Formosa Plastics Corporation, U.S.A.

  公开号：EP3212705B1

  公开（公告）日：2021-03-10
• Method for treating B cell regulated autoimmune disorders
  申请人：Foley Kevin

  公开号：US20070032493A1

  公开（公告）日：2007-02-08

  The invention relates to a method for treating B-cell regulated autoimmune disorders using compounds that modulate the activity of c-Rel.
• PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS
  申请人：Kostik Elena

  公开号：US20090163708A1

  公开（公告）日：2009-06-25

  This invention relates to a method of preparing mesylate salts of compounds that inhibit IL-12, IL-23 and/or IL-27 production.