(ethylenediamine-N,N'-diacetato)cobalt(II) | 29977-10-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (ethylenediamine-N,N'-diacetato)cobalt(II)
• CAS: 29977-10-4
• 化学式: C₆H₁₀CoN₂O₄
• 分子量: 233.15
• InChiKey: WEZLCHAXGMDHJP-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.34
• 重原子数：
  13.0
• 可旋转键数：
  7.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  104.32
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  (ethylenediamine-N,N'-diacetato)cobalt(II) 在 水 、 氧气 作用下， 以 水 为溶剂， 生成 bis(ethylenediamine-N,N'-diacetato)(μ-peroxo)(μ-hydroxo) dicobalt(III)
  参考文献：
  名称：

  某些钴（II）螯合物与空气氧相互作用的动力学：形成两个氮氧的载体

  摘要：

  研究了氨基酸衍生物EBAA ***的钴（II）螯合物可逆吸收水溶液中空气氧的热力学和动力学。动力学数据支持Wilkins [1]报道的机理。已经根据氧合反应CoL + O 2 →CoLO 2的速率常数k 1的温度依赖性确定了活化的焓和熵。不利的熵项几乎完全抵消了氧结合的有利焓。讨论了这些实验常数之间的关系，配合物的电子结构以及根据早期研究得出的结果的意义。

  DOI：

  10.1016/0304-5102(90)85200-2

文献信息

• Synthesis, Characterization, and Optical Resolution of Electrically Neutral Octahedral Cobalt(III) Complexes Containing the Tetradentate Ligand
  作者：Hiroshi Nakazawa、Hisaka Ohtsuru、Hayami Yoneda

  DOI：10.1246/bcsj.60.525

  日期：1987.2

  (gly), β-alaninato (β-ala), have been synthesized and characterized. They have been completely resolved into the enantiomers, except unsym-cis-fac-[Co(edda)(β-ala)], by the bis(μ-d-tartrato)diantimonate(III) anion, [Sb2(d-tart)2]2−, form of QAE-Sephadex resin with water as the eluent, and their absolute configurations have been determined based upon the circular dichroism spectra. It has been revealed that

  已经合成并表征了 [Co(edda)(aa)] 的三种几何异构体，其中 edda=N',N-乙二胺二乙酸根、aa=glycinato (gly)、β-alaninato (β-ala)。除了 unsym-cis-fac-[Co(edda)(β-ala)] 外，它们已被双（μ-d-酒石酸）二锑酸根（III）阴离子完全分解为对映体，[Sb2(d-tart )2]2-, 以水为洗脱液的 QAE-Sephadex 树脂形式，其绝对构型已根据圆二色光谱确定。已经表明，与 Λ 对映体相比，[Sb2(d-tart)2]2- 更倾向于 Δ 对映体，而与几何异构体的种类无关。已经提出了对光学分辨率机制的考虑。
• N-hydroxymethylation of ethylene-bridged glycine metal(II) complexes by formaldehyde
  作者：Chew-Hee Ng、Soon-Beng Teo、Siang-Guan Teoh、Hoong-Kun Fun、Jean-Paul Declercq

  DOI：10.1016/s0020-1693(02)01092-7

  日期：2002.11

  The (N,N'-ethylenediglycinato)metal(II) complexes, M(edg) (M = Cu, Zn, Ni, Co) undergo N-hydroxymethylation with formaldehyde in the pH range similar to3.5-9.5 to yield the respective [N,N'-ethylenedi(N-hydroxymethyl-glycinato)]metal(II), ML x H2O (L = N,N'-ethylenedi(N-hydroxymethylglycinate); x = 4, 4.5). The crystal and molecular structures of the Ni(edg) 3H(2)O and ML 4H(2)O (M = Ni, Cu, Co) complexes have been determined; all the complexes have distorted octahedral geometries and their tetradentate ligands have oc-cis configuration. Analysis of these structures also shows that the N-hydroxymethylated ligands are stereospecifically coordinated. However, M(edg) do not undergo Mannich ammomethylation with formaldehyde and ammonia. In the reactions studied, the alpha-carbon of M(edg) is unaffected by formaldehyde attack. No further condensation of the N-hydroxymethyl substituents and their potential reactivity are also explained. (C) 2002 Elsevier Science B.V. All rights reserved.