苯基三乙基氢氧化铵 | 7620-71-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 苯基三乙基氢氧化铵
• 英文名称: triethylbenzylammonium hydroxide
• 英文别名: triethylphenylammonium hydroxide；tri-N-ethyl-anilinium; hydroxide；Tri-N-aethyl-anilinium; Hydroxid；N,N,N-triethylanilinium hydroxide；Benzenaminium, N,N,N-triethyl-, hydroxide；triethyl(phenyl)azanium;hydroxide
• CAS: 7620-71-5
• 化学式: C₁₂H₂₀N*HO
• 分子量: 195.305
• InChiKey: GPHXJBZAVNFMKX-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.88
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

SDS

Name:	Triethylphenylammonium Hydroxide (10% in Water) Material Safety Data Sheet
Synonym:	N, N, N-Triethylbenzeneammonium Hydroxid
CAS:	7620-71-5

Section 1 - Chemical Product MSDS Name:Triethylphenylammonium Hydroxide (10% in Water) Material Safety Data Sheet
Synonym:N, N, N-Triethylbenzeneammonium Hydroxid

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
7620-71-5	Benzenaminium, N,N,N-Triethyl-, Hydrox	10	231-533-9

Hazard Symbols: C
Risk Phrases: 34

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
None

---

Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode if exposed to fire.
Extinguishing Media:
Cool containers with flooding quantities of water until well after fire is out. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation.
Discard contaminated shoes.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7620-71-5: CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: clear, colorless
Odor: ammonia-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: > 100 deg C
Freezing/Melting Point: > 0 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H21NO
Molecular Weight: 195.30

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen oxides (NOx) and ammonia (NH3).
Hazardous Polymerization: Has not been reported

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7620-71-5 unlisted.
CAS# 7732-18-5: ZC0110000 LD50/LC50:
Not available.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Benzenaminium, N,N,N-Triethyl-, Hydroxide - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

---

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: CORROSIVE LIQUID, N.O.S.*
Hazard Class: 8
UN Number: 1760
Packing Group: III
IMO
Shipping Name: CORROSIVE LIQUID, N.O.S.
Hazard Class: 8
UN Number: 1760
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE LIQUID, N.O.S.
Hazard Class: 8
UN Number: 1760
Packing group: III

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 25 Avoid contact with eyes.
S 28 After contact with skin, wash immediately
with...
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 7620-71-5: No information available.
CAS# 7732-18-5: No information available.
Canada
CAS# 7620-71-5 is listed on Canada's NDSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 7620-71-5 is not listed on Canada's Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7620-71-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  苯基三乙基氢氧化铵 、 左啡诺 生成 3-ethoxy-17-methyl-morphinane
  参考文献：
  名称：

  氧化吗啡烷。（3. Mitteilung）。光学活性3-氧吗啡烷

  摘要：

  光学显微镜中的3-Oxy-N-烷基-吗啡烷被烧成灰烬，而在ther和Esterübergeführt中则消失了。

  DOI：

  10.1002/hlca.19510340715
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 silver(l) oxide 作用下， 生成 苯基三乙基氢氧化铵
  参考文献：
  名称：

  Hofmann,A.W., Justus Liebigs Annalen der Chemie, 1851, vol. 79, p. 18

  摘要：

  DOI：
• 作为试剂：
  描述：

  氰乙酸乙酯 在 氢溴酸 、 苯基三乙基氢氧化铵 、 dioxide titanium 作用下， 以 水 为溶剂， 106.0 ℃ 、500.01 kPa 条件下， 反应 0.4h， 生成 2-溴烟酸乙酯
  参考文献：
  名称：

  一种水热法合成2－卤代烟酸酯和2－卤代烟 酸的方法

  摘要：

  本发明公开了一种水热法合成2－卤代烟酸酯和2－卤代烟酸的方法，涉及化学合成领域。该方法由取代氨基丙烯醛、催化剂、催化剂助剂、水、氰基乙酸酯为原料，采用水热法法合成2－卤代烟酸酯和2－卤代烟酸。与现有技术相比，本发明的合成方法具有绿色环保、易于分离，产品收率高、质量好等特点，更利于实现大规模工业化生产。

  公开号：

  CN106349157B

文献信息

• PROCESS FOR PREPARING DIARYL OXALATE
  申请人：Tanaka Shuji

  公开号：US20120296063A1

  公开（公告）日：2012-11-22

  Disclosed is a process for preparing a diaryl oxalate which comprises the step of transesterifying a dialkyl oxalate or/and an alkylaryl oxalate with an aryl alcohol in the presence of a tetra(aryloxy)titanium as a catalyst, wherein the tetra(aryloxy)titanium is fed into a reaction system of the transesterification as an aryl alcohol solution of the tetra(aryloxy)titanium which is prepared by reacting a tetraalkoxy titanium and an excess amount of the aryl alcohol and removing a by-producing alkyl alcohol.

  揭示了一种制备二芳基草酸酯的方法，包括在四(芳氧基)钛存在下，通过将二烷基草酸酯和/或烷基芳基草酸酯与芳基醇进行酯交换的步骤，其中四(芳氧基)钛以芳基醇溶液的形式加入酯交换的反应系统中，该芳基醇溶液是通过将四烷氧基钛和过量的芳基醇反应制备的，并去除生成的副产物烷基醇。
• Method for Producing Fluorine-Containing Cyclopropane Carboxylic Acid Compound
  申请人：CENTRAL GLASS COMPANY, LIMITED

  公开号：US20180186763A1

  公开（公告）日：2018-07-05

  The present invention provides an industrially applicable method for production of a fluorine-containing cyclopropane carboxylic acid compound useful as an intermediate for pharmaceutical and agrichemical products. A fluorine-containing cyclopropane monoester is obtained by: forming a fluorine-containing cyclic sulfate with the use of a fluorine-containing dial compound and sulfuryl fluoride (as a cyclic sulfuric esterification step); reacting the fluorine-containing cyclic sulfate with a malonic diester, thereby forming a fluorine-containing cyclopropane diester (as a cyclopropanation step); and hydrolyzing the fluorine-containing cyclopropane diester (as a hydrolysis step). The fluorine-containing cyclopropane carboxylic acid compound, such as fluorine-containing cyclopropane monoester or its salt, can be obtained with high chemical and optical purity by mixing the fluorine-containing cyclopropane monoester with an amine and subjecting the resulting salt of the fluorine-containing cyclopropane monoester and amine to recrystallization purification.

  本发明提供了一种工业上可应用的生产含氟环丙烷羧酸化合物的方法，该化合物可用作制药和农药产品的中间体。通过以下步骤获得含氟环丙烷单酯：使用含氟二醇化合物和氟磺酰氟形成含氟环状硫酸酯（作为环状硫酸酯化步骤）；将含氟环状硫酸酯与丙二酸二酯反应，从而形成含氟环丙烷二酯（作为环丙烷化步骤）；并水解含氟环丙烷二酯（作为水解步骤）。通过将含氟环丙烷单酯与胺混合并将所得的含氟环丙烷单酯和胺的盐进行重结晶纯化，可以获得高化学和光学纯度的含氟环丙烷羧酸化合物，例如含氟环丙烷单酯或其盐。
• SEMI-PERMEABLE PARTICLES HAVING METALLIC CATALYSTS AND USES
  申请人：Robello Douglas R.

  公开号：US20140148330A1

  公开（公告）日：2014-05-29

  Semi-permeable particle can be used to facilitate chemical reactions. The semi-permeable particles are permeable to molecules having a molar mass of 1000 Daltons or less, have a mode particle size of at least 1 μm, and comprise nanoparticles of catalytically active metallic materials disposed within at least some of multiple discrete cavities in the continuous polymeric phase. The nanoparticles of catalytically active metallic materials (a) comprise one or more elements selected from Groups 8, 9, 10, and 11 of the Periodic Table, and (b) have an effective diameter of at least 1 nm and up to and including 200 nm.

  半透性颗粒可用于促进化学反应。这些半透性颗粒对分子摩尔质量为1000道尔顿或更低的分子是可渗透的，具有至少1微米的模式颗粒大小，并包括催化活性金属材料的纳米颗粒，其分布在连续聚合物相的多个离散空腔中。催化活性金属材料的纳米颗粒(a)包括周期表8、9、10和11组中选择的一个或多个元素，且(b)具有至少1纳米且最大直径为200纳米的有效直径。
• Thiomolybdate analogues and uses thereof
  申请人：——

  公开号：US20040019043A1

  公开（公告）日：2004-01-29

  The current invention provides novel thiomolybdate derivatives, methods of making novel thiomolybdate derivatives, pharmaceutical compositions of novel thiomolybdate derivatives, methods of using novel thiomolybdate derivatives to treat diseases associated with aberrant vascularization and methods of using pharmaceutical compositions of thiomolybdate derivatives to treat diseases associated with aberrant vascularization.

  当前的发明提供了新颖的硫代钼酸盐衍生物，制备新颖的硫代钼酸盐衍生物的方法，新颖的硫代钼酸盐衍生物的药物组合物，使用新颖的硫代钼酸盐衍生物治疗与异常血管生成相关的疾病的方法，以及使用硫代钼酸盐衍生物药物组合物治疗与异常血管生成相关的疾病的方法。
• Process for producing an aromatic polycarbonate
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：US20030166826A1

  公开（公告）日：2003-09-04

  To produce an aromatic polycarbonate excellent in physical properties and hue by a simplified step as compared with a conventional one. A process for producing an aromatic polycarbonate, which comprises the following steps (1) to (3): (1) a step of reacting phenol with acetone in the presence of an acid catalyst to convert part of the phenol into bisphenol A, to obtain a bisphenol A/phenol composition, (2) a step of supplying the bisphenol A/phenol composition held in a molten state in a liquid form to an aromatic polycarbonate production step, and (3) a step of reacting the bisphenol A and a carbonate material to produce an aromatic polycarbonate.

  通过比传统方法简化步骤，生产出物理性能和色泽优异的芳香族聚碳酸酯。生产芳香族聚碳酸酯的方法包括以下步骤（1）至（3）：（1）在酸催化剂的存在下，将苯酚与丙酮反应，将部分苯酚转化为双酚A，获得双酚A/苯酚组成的混合物，（2）将保持熔化状态的双酚A/苯酚混合物以液态形式供给芳香族聚碳酸酯生产步骤，（3）将双酚A和碳酸酯材料反应，生产出芳香族聚碳酸酯。