(2R)-2-[[(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2R)-2-[[(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoate
• 化学式: C12H16N2O4
• 分子量: 252.27
• InChiKey: NLKUJNGEGZDXGO-XCBNKYQSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  113
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• US4127535A
  申请人：——

  公开号：US4127535A

  公开（公告）日：1978-11-28
• US4242256A
  申请人：——

  公开号：US4242256A

  公开（公告）日：1980-12-30
• [EN] A METHOD OF PRODUCING AN N-BLOCKED BIPHALIN INTERMEDIATE<br/>[FR] PROCÉDÉ DE PRODUCTION D'UN INTERMÉDIAIRE DE BIPHALINE N-BLOQUÉ
  申请人：INST MEDYCYNY DOSWIADCZALNEJ I

  公开号：WO2009093918A1

  公开（公告）日：2009-07-30

  The perspective uses of using an opioid peptide commonly called biphaline as a drag require the design of economical synthesis methods of said peptide. It was shown that N- blocked dipeptide and tripeptide fragments used in the synthesis for use in the synthesis may be obtained through the modification of the synthesis, which is based on the acylation of an appropriate organic amino-acid salt using an appropriate active derivative of tyrosine or dipeptide.
• [EN] DYE COMPOSITION COMPRISING A GLYCOSYL IRIDOID COMPOUND AND A PARTICULAR ALDEHYDE OR IMINE, DYEING PROCESS AND DEVICES THEREFOR<br/>[FR] COMPOSITION DE COLORANT COMPRENANT UN COMPOSÉ IRIDOÏDE GLYCOSYLIQUE ET UN ALDÉHYDE PARTICULIER OU UNE IMINE PARTICULIÈRE, PROCÉDÉ DE COLORATION ET DISPOSITIFS S'Y RAPPORTANT
  申请人：OREAL

  公开号：WO2013045704A2

  公开（公告）日：2013-04-04

  The present invention relates to a composition for dyeing human keratin fibres, comprising, in a cosmetically acceptable medium: * a compound of the iridoid family of formula (I) below, or a plant extract comprising the same: in which R1: hydrogen, methyl, hydroxymethyl, aldehyde; -CO2R4 in which R4: hydrogen, C1-C2 alkyl; sugar; R2: a hydrogen atom, a hydroxyl radical, sugar radical; R3: hydrogen, hydroxyl, alkyloxy; R: sugar radical (aldose or derivative); integer ranging from 1 to 5; the compound(s) of formula (I) having optionally undergone a preliminary step consisting in replacing the radical R with a hydrogen atom, performed using an enzyme; ** at least one aldehyde or imine compound of formulae (i) and (ii), and also oxidized oligo- or polysaccharide comprising at least one aldehyde or imine function: with n equal to 0 or 1; X: O, NR'1; A: COOH, optionally substituted aryl, cationic or non-cationic, saturated or unsaturated 5- or 6-membered heterocycle, comprising one or two heteroatoms, optionally substituted, alkyl, alkenyl; A2 divalent alkylene; the compounds possibly being, in the case of aldehydes, in acetal or hemiacetal form. The invention also relates to a process using such a composition, and also to multi-compartment devices.
• [EN] DYEING PROCESS USING A COMPOSITION COMPRISING A GLYCOSYL IRIDOID COMPOUND AND A NUCLEOPHILE OR AN AMINO OR THIO POLYMER, COMPOSITION AND DEVICES THEREFOR<br/>[FR] PROCÉDÉ DE COLORATION UTILISANT UNE COMPOSITION COMPRENANT UN COMPOSÉ IRIDOÏDE GLYCOSYLIQUE ET UN NUCLÉOPHILE OU UN POLYMÈRE AMINÉ OU THIOLÉ ET COMPOSITION ET DISPOSITIFS S'Y RAPPORTANT
  申请人：OREAL

  公开号：WO2013045701A2

  公开（公告）日：2013-04-04

  The present invention relates to a process of dyeing human keratin fibres by applying a composition, comprising, in a cosmetically acceptable medium: * a compound of the iridoid family of formula (I) below, or a plant extract comprising the same: formula (I) in which hydrogen, methyl, hydroxymethyl, aldehyde; -CO2R4 in which R4: hydrogen, C1-C2 alkyl; sugar; R2: a hydrogen atom, a hydroxyl radical, sugar radical; R3: hydrogen, hydroxyl, alkyloxy; R: sugar radical (aldose or derivative); integer ranging from 1 to 5; the compound(s) of formula (I) having undergone prior to or simultaneously with the dyeing process, a step consisting in replacing the radical R with a hydrogen atom; ** at least one particular nucleophilic compound or at least one amino or thio polymer, in an amino or thio polymer(s)/compound(s) of formulae (I) and/or (II) weight ratio of at least 0.01. The invention also relates to multi-compartment devices.