sodium;2,3,5,6-tetrahydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: sodium;2,3,5,6-tetrahydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate
• 化学式: C12H21NaO12
• 分子量: 380.28
• InChiKey: AQKFVNLHZYOMKQ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -10.0
• 重原子数：
  25
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  220
• 氢给体数：
  8
• 氢受体数：
  12

文献信息

• A METHOD OF TRANSPORTING MESENCHYMAL STEM CELLS BY MEANS OF A TRANSPORTING SOLUTION AND A METHOD OF ADMINISTERING STEM CELLS TO WOUNDS
  申请人：CellResearch Corporation Pte. Ltd.

  公开号：EP3772936A1

  公开（公告）日：2021-02-17
• METHOD OF TRANSPORTING MESENCHYMAL STEM CELLS BY MEANS OF A TRANSPORTING SOLUTION AND A METHOD OF ADMINISTERING STEM CELLS TO WOUNDS
  申请人：Cellresearch Corporation Pte. Ltd.

  公开号：US20190307805A1

  公开（公告）日：2019-10-10

  The present invention relates to a method of transporting a stem cell population, the method comprising transporting the stem cell population contacted with a liquid carrier. In addition, the present invention concerns a method of treating a subject having a disease, the method comprising topically administering a defined mesenchymal stem cell population to the subject, wherein the mesenchymal stem cell population is administered within about 96 hours from the time point the mesenchymal stem cell population has been harvested. Also concerned is a unit dosage comprising about 20 million cells, of about 15 million cells, of about 10 million cells, of about 5 million cells, of about 4 million cells, of about 3 million cells, of about 2 million cells, of about 1 million cells, of about 0.5 million cells, of about 0.25 million cells or of less than 0.25 million cells of a defined mesenchymal stem cell population.
• MESENCHYMAL STEM CELL STORING OR TRANSPORT FORMULATION AND METHODS OF MAKING AND USING THE SAME
  申请人：CELLRESEARCH CORPORATION PTE. LTD.

  公开号：US20210102171A1

  公开（公告）日：2021-04-08

  The present invention relates to a mesenchymal stem cell storing or transport formulation, a method of preparing the mesenchymal stem cell toring or transport formulation as well as to methods of using the mesenchymal stem cell storing or transport formulation. Such methods include a method of transporting mesenchymal stem cells in this storing or transport formulation as well as a method of treating a subject having a disease, the method comprising topically administering mesenchymal stem cells that have been stored or transported in this storing or transport formulation. Also concerned is a unit dosage of the mesenchymal stem cells.
• [EN] A METHOD OF TRANSPORTING MESENCHYMAL STEM CELLS BY MEANS OF A TRANSPORTING SOLUTION AND A METHOD OF ADMINISTERING STEM CELLS TO WOUNDS<br/>[FR] PROCÉDÉ DE TRANSPORT DE CELLULES SOUCHES MÉSENCHYMATEUSES AU MOYEN D'UNE SOLUTION DE TRANSPORT ET PROCÉDÉ D'ADMINISTRATION DE CELLULES SOUCHES À DES PLAIES
  申请人：CELLRESEARCH CORP PTE LTD

  公开号：WO2019199229A1

  公开（公告）日：2019-10-17

  The present invention relates to a method of transporting a stem cell population, the method comprising transporting the stem cell population contacted with a liquid carrier. In the preferred embodiment, the liquid carrier is Hypothermosol and comprises Trolox e.g. Hypothermosol-FRS. In addition, the present invention concerns a method of treating a subject having a disease such as a wound, the method comprising topically administering a defined mesenchymal stem cell population to the subject, wherein the mesenchymal stem cell population is administered within about 96 hours from the time point the mesenchymal stem cell population has been harvested. Also concerned is a unit dosage comprising the defined mesenchymal stem cell population such as from the amniotic membrane of the umbilical cord, wherein at least 90% of the cells express each of CD73, CD90 and CD105.
• [EN] A MESENCHYMAL STEM CELL STORING OR TRANSPORT FORMULATION AND METHODS OF MAKING AND USING THE SAME<br/>[FR] FORMULATION DE STOCKAGE OU DE TRANSPORT DE CELLULES SOUCHES MÉSENCHYMATEUSES ET SES PROCÉDÉS DE FABRICATION ET D'UTILISATION
  申请人：CELLRESEARCH CORP PTE LTD

  公开号：WO2021071430A1

  公开（公告）日：2021-04-15

  The disclosure relates to a mesenchymal stem cell storing or transport formulation, a method of preparing and using said formulation. It also includes a method of treating a subject having a disease such as a wound by topically administering mesenchymal stem cells that have been stored or transported in the storing or transport formulation. Also concerned is a unit dosage of the mesenchymal stem cells. In the preferred embodiment, the formulation comprises HypoThermosol®, human serum albumin and Plasmalyte.