Difluoro-(1,1,2,2-tetrafluoro-2-fluorosulfonyl-ethoxy)-acetic acid | 88986-29-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 磺酰卤
• 英文名称: Difluoro-(1,1,2,2-tetrafluoro-2-fluorosulfonyl-ethoxy)-acetic acid
• 英文别名: Difluoro[1,1,2,2-tetrafluoro-2-(fluorosulfonyl)ethoxy]acetic acid；2,2-difluoro-2-(1,1,2,2-tetrafluoro-2-fluorosulfonylethoxy)acetic acid
• CAS: 88986-29-2
• 化学式: C₄HF₇O₅S
• 分子量: 294.104
• InChiKey: CXPATAQWPLQLIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  89
• 氢给体数：
  1
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  Difluoro-(1,1,2,2-tetrafluoro-2-fluorosulfonyl-ethoxy)-acetic acid 在 氯化亚砜 、 N,N-二甲基甲酰胺 作用下， 生成 C₄ClF₇O₄S
  参考文献：
  名称：

  Syntheses of a Perfluoroethanesulfonyl Fluoride Vinyl Ether

  摘要：

  The target monomer, perfluoroethanesulfonyl fluoride vinyl ether 8, was obtained from the starting material, iodoperfluoroethanesulfonyl fluoride 1, through the intermediate, acyl fluoride 4. Two different synthetic routes were utilized in the conversion of 4 to 8.

  DOI：

  10.1021/jo102409s
• 作为产物：
  描述：

  2-(2-碘-四氟乙氧基)四氟乙基硫酰氟 在 硫酸 、 三氧化硫 作用下， 以88.5%的产率得到Difluoro-(1,1,2,2-tetrafluoro-2-fluorosulfonyl-ethoxy)-acetic acid
  参考文献：
  名称：

  Syntheses of a Perfluoroethanesulfonyl Fluoride Vinyl Ether

  摘要：

  The target monomer, perfluoroethanesulfonyl fluoride vinyl ether 8, was obtained from the starting material, iodoperfluoroethanesulfonyl fluoride 1, through the intermediate, acyl fluoride 4. Two different synthetic routes were utilized in the conversion of 4 to 8.

  DOI：

  10.1021/jo102409s

文献信息

• Potassium 3-oxa-ω-fluorosulfonylperfluoropentanoate (FO2SCF2CF2OCF2CO2K), a low-temperature trifluoromethylating agent for organic halides; its α-carbon-oxygen bond fragmentation
  作者：Zheng-Yu Long、Jian-Xin Duan、Yuan-Bin Lin、Cai-Yun Guo、Qing-Yun Chen

  DOI：10.1016/0022-1139(96)03438-0

  日期：1996.6

  The trifluoromethylation of organic halides with FO2SCF2CF2OCF2CO2K (1) in DMF can be accomplished at 45 °C which is advantageous for thermally sensitive substrates. α-Carbon-oxygen bond fragmentation of 1 and the related β-carbon-oxygen bond scission are discussed.

  在DMF中用FO 2 SCF 2 CF 2 OCF 2 CO 2 K （1）对有机卤化物进行三氟甲基化可以在45°C的温度下完成，这对热敏性基材是有利的。α的-碳-氧键断裂1和相关的β碳上-氧键断裂进行了讨论。
• ACTA CHIM. SIN., 1983, 41, N 10, 946-959
  作者：

  DOI：——

  日期：——
• Syntheses of a Perfluoroethanesulfonyl Fluoride Vinyl Ether
  作者：Changqing Lu、Wanchao Jiang、Tom Hickman、Darryl D. DesMarteau

  DOI：10.1021/jo102409s

  日期：2011.4.15

  The target monomer, perfluoroethanesulfonyl fluoride vinyl ether 8, was obtained from the starting material, iodoperfluoroethanesulfonyl fluoride 1, through the intermediate, acyl fluoride 4. Two different synthetic routes were utilized in the conversion of 4 to 8.