N,N'-dimethyl-trans-1,4-cyclohexanedicarboxamide | 101199-73-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N'-dimethyl-trans-1,4-cyclohexanedicarboxamide
• 英文别名: 1-N,4-N-dimethylcyclohexane-1,4-dicarboxamide
• CAS: 101199-73-9
• 化学式: C₁₀H₁₈N₂O₂
• mdl: MFCD24389717
• 分子量: 198.265
• InChiKey: ZKVWMNOPTCJCGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE 、 甲胺 生成 N,N'-dimethyl-trans-1,4-cyclohexanedicarboxamide
  参考文献：
  名称：

  一些取代酰胺的偶极矩方向的实验确定和分析

  摘要：

  DOI：

  10.1021/j100401a048

文献信息

• Molecular Catalysts for Selective Hydrogenolysis of Amides
  申请人：Eastman Chemical Company

  公开号：US20190345178A1

  公开（公告）日：2019-11-14

  A compound by the name 1,1,1-tris(di(3,5-dimethoxyphenyl)phosphino-methyl)ethane. The compound can be represented by the structure of formula (I): The compound is useful as a ligand for ruthenium to form an organometallic complex. The complex is an active catalyst for the hydrogenolysis of amides to form amines and optionally alcohols.

  一种名为1,1,1-三(di(3,5-二甲氧基苯基)磷酰基甲基)乙烷的化合物。该化合物可用化学式(I)的结构表示：该化合物可作为一种配体用于与钌形成有机金属配合物。该配合物是一种活性催化剂，可用于酰胺的氢解反应，生成胺和可选的醇。
• Immobilized ruthenium-triphos catalysts for selective hydrogenolysis of amides
  申请人：Eastman Chemical Company

  公开号：US10682636B2

  公开（公告）日：2020-06-16

  A compound represented by the structure of formula (I): The compound is useful as a ligand for ruthenium to form an organometallic complex. The complex may be immobilized on an oxidic support to form an active, heterogeneous catalyst for the hydrogenolysis of amides to form amines and optionally alcohols.

  由式 (I) 结构代表的化合物： 该化合物可作为钌的配体，形成有机金属络合物。该配合物可固定在氧化性载体上，形成一种活性异相催化剂，用于氢解酰胺形成胺和醇。
• Molecular catalysts for selective hydrogenolysis of amides
  申请人：Eastman Chemical Company

  公开号：US11111257B2

  公开（公告）日：2021-09-07

  A compound by the name 1,1,1-tris(di(3,5-dimethoxyphenyl)phosphino-methyl)ethane. The compound can be represented by the structure of formula (I): The compound is useful as a ligand for ruthenium to form an organometallic complex. The complex is an active catalyst for the hydrogenolysis of amides to form amines and optionally alcohols.

  一种名称为 1,1,1-三(二(3,5-二甲氧基苯基)膦甲基)乙烷的化合物。该化合物可用式 (I) 结构表示： 该化合物可用作钌的配体，形成有机金属配合物。该配合物是一种活性催化剂，可用于酰胺的氢解，生成胺和醇。
• Modifiable polyunsaturated polymers and processes for their preparation
  申请人：Parthiban Anbanandam

  公开号：US20060189774A1

  公开（公告）日：2006-08-24

  The present invention relates to modifiable linear polyunsaturated polymers and processes for preparing the same comprising reacting solely at least one bifunctional nucleophilic compound with at least one α-functional unsaturated monomer. The at least one bifunctional nucleophilic compound of the invention comprises two nucleophiles independently selected from the group consisting of C, N, O, S and Se. The at least one α-functional unsaturated monomer of the invention comprises two leaving groups L 1 and L 2 , wherein at least one of the leaving groups L 1 and L 2 of the at least one α-functional unsaturated monomer is part of the nonaromatic unsaturated structure C═C—C α -L. The double bond of said α-functional unsaturated monomer is maintained in the polyunsaturated polymer.

  本发明涉及可改性线性多不饱和聚合物以及制备该聚合物的工艺，包括仅使至少一种双官能团亲核化合物与至少一种α官能团不饱和单体反应。本发明的至少一种双官能团亲核化合物包括两个独立选自 C、N、O、S 和 Se 组的亲核物。本发明的至少一种 α-官能团不饱和单体包括两个离去基团 L 1 和 L 2 其中至少一个离去基团 L 1 和 L 2 的至少一个离去基团 L 1 和 L 2 是非芳香族不饱和结构 C═C-C α -L.所述 α-官能团不饱和单体的双键保留在多不饱和聚合物中。
• IAP BIR DOMAIN BINDING COMPOUNDS
  申请人：Pharmascience Inc.

  公开号：US20130071411A1

  公开（公告）日：2013-03-21

  Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I or II or a salt thereof, in which R 1 , R 2 , R 3 , R 100 , R 200 , R 300 , A, A 1 , BG, Q and Q 1 are substituents described herein. Also disclosed is the use of compounds of Formula I and II to treat proliferative disorders such as cancer.