3-morpholino-5-methylphenol | 60541-54-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 3-morpholino-5-methylphenol
• 英文别名: m-N-Morpholino-m-kresol；3-Methyl-5-morpholino-phenol；3-methyl-5-morpholin-4-yl-phenol；3-Methyl-5-morpholin-4-ylphenol
• CAS: 60541-54-0
• 化学式: C₁₁H₁₅NO₂
• 分子量: 193.246
• InChiKey: OUGOBFAXBAGTEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  32.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-Hydroxy-4-methyl-6-morpholino-benzoesaeuremethylester 在 氢氧化钾 作用下， 以30 mg的产率得到3-morpholino-5-methylphenol
  参考文献：
  名称：

  Kang, G. J.; Chan, T. H., Canadian Journal of Chemistry, 1985, vol. 63, p. 3102 - 3110

  摘要：

  DOI：

文献信息

• Novel amino acid ester and reagent composition for detecting leucocytes or elastase in body liquid
  申请人：KYOTO DAIICHI KAGAKU CO., LTD.

  公开号：EP0661280A1

  公开（公告）日：1995-07-05

  An amino acid ester of the formula: (X-O-A-)n-Y in which X is derived from an aromatic or heterocyclic compound: X-OH or its derivative; A is a residue of a L-amino acid, n is an integer of at least 2, and Y is a N-substituent of an amino acid derived from a compound having the same or different two or more carbonyl or sulfonyl groups which is formed from a single or complex compound selected from the group consisting of noncyclic or cyclic hydrocarbons having 1 to 10 carbon atoms, saturated or unsaturated heterocyclic compounds, aromatic compounds, organosilicon compounds having 1 to 10 silicon atoms, monosaccharides and oligosaccharide comprising 2 to 10 monosaccharides, all of which may have a substituent and/or a hetero atom to form the complex, which ester is specifically hydrolyzed by leucocytes or elastase.

  公式为(X-O-A-)n-Y的氨基酸酯，其中X源自芳香族或杂环化合物：X-OH或其衍生物；A是L-氨基酸的残基，n是至少为2的整数，Y是源自具有相同或不同的两个或更多个羰基或磺酰基的化合物的氨基酸的N-取代基，该化合物由选择自非环烃或环烃的群组成的单一或复杂化合物形成，该群包括具有1至10个碳原子的饱和或不饱和杂环化合物、芳香族化合物、具有1至10个硅原子的有机硅化合物、由2至10个单糖组成的单糖和寡糖，所有这些化合物均可具有取代基和/或杂原子以形成复合物，该酯特异地被白细胞或弹性蛋白酶水解。
• KANG, G. J.;CHAN, T. H., CAN. J. CHEM., 1985, 63, N 11, 3102-3110
  作者：KANG, G. J.、CHAN, T. H.

  DOI：——

  日期：——