4-tert-butyl-2-(1H-imidazol-1-yl)pyridine | 1261616-69-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-tert-butyl-2-(1H-imidazol-1-yl)pyridine
• 英文别名: 4-Tert-butyl-2-imidazol-1-ylpyridine；4-tert-butyl-2-imidazol-1-ylpyridine
• CAS: 1261616-69-6
• 化学式: C₁₂H₁₅N₃
• 分子量: 201.271
• InChiKey: RYCKUWSYDVOQHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-tert-butyl-2-(1H-imidazol-1-yl)pyridine 、 碘甲烷 以 乙酸乙酯 为溶剂， 反应 15.0h， 以74%的产率得到1-(4-(tert-butyl)pyridin-2-yl)-3-methyl-1H-imidazol-3-ium iodide
  参考文献：
  名称：

  A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation

  摘要：

  The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.10.059
• 作为产物：
  描述：

  咪唑 、 2-溴-4-叔丁基吡啶 在 copper(l) iodide 、 potassium carbonate 、 L-脯氨酸 作用下， 以 二甲基亚砜 为溶剂， 反应 47.0h， 以57%的产率得到4-tert-butyl-2-(1H-imidazol-1-yl)pyridine
  参考文献：
  名称：

  A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation

  摘要：

  The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.10.059

文献信息

• Platinum complex having carbene fragment, OLED using the same, and nitrogen-containing heterocyclic bidentate chelate having carbene unit
  申请人：National Tsing Hua University

  公开号：US10170709B2

  公开（公告）日：2019-01-01

  A platinum complex having at least one carbene fragment, and an OLED using the same are described. The platinum complex contains a platinum cation, a zero-valent nitrogen-containing heterocyclic bidentate chelate, and a dianionic nitrogen-containing heterocyclic bidentate chelate. The zero-valent nitrogen-containing heterocyclic bidentate chelate has at least one carbene unit coordinating to platinum. The dianionic nitrogen-containing heterocyclic bidentate chelate has at least one electron-withdrawing substituent, and forms two N—Pt bonds, or one N—Pt bond and one C—Pt bond, with the central platinum cation.

  本文描述了一种具有至少一个碳烯片段的铂络合物，以及使用该铂络合物的 OLED。铂络合物包含铂阳离子、零价含氮杂环双叉螯合物和二价含氮杂环双叉螯合物。零价含氮杂环双叉螯合物至少有一个碳烯单元与铂配位。二价含氮杂环双叉螯合物具有至少一个抽电子取代基，并与中心铂阳离子形成两个 N-Pt 键，或一个 N-Pt 键和一个 C-Pt 键。
• PLATINUM COMPLEX HAVING CARBENE FRAGMENT, OLED USING THE SAME, AND NITROGEN-CONTAINING HETEROCYCLIC BIDENTATE CHELATE HAVING CARBENE UNIT
  申请人：National Tsing Hua University

  公开号：US20170005279A1

  公开（公告）日：2017-01-05

  A platinum complex having at least one carbene fragment, and an OLED using the same are described. The platinum complex contains a platinum cation, a zero-valent nitrogen-containing heterocyclic bidentate chelate, and a dianionic nitrogen-containing heterocyclic bidentate chelate. The zero-valent nitrogen-containing heterocyclic bidentate chelate has at least one carbene unit coordinating to platinum. The dianionic nitrogen-containing heterocyclic bidentate chelate has at least one electron-withdrawing substituent, and forms two N—Pt bonds, or one N—Pt bond and one C—Pt bond, with the central platinum cation.
• A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation
  作者：Martin Peters、Rolf Breinbauer

  DOI：10.1016/j.tetlet.2010.10.059

  日期：2010.12

  The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported. (C) 2010 Elsevier Ltd. All rights reserved.