2-Butenoic acid, 4-(dimethylamino)-4-oxo-, (2Z)- | 2564-94-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Butenoic acid, 4-(dimethylamino)-4-oxo-, (2Z)-
• 英文别名: 4-(dimethylamino)-4-oxobut-2-enoic acid
• CAS: 2564-94-5
• 化学式: C₆H₉NO₃
• 分子量: 143.14
• InChiKey: UWVCKXVPDINNHW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof
  申请人：Ham Young Jin

  公开号：US20080009509A1

  公开（公告）日：2008-01-10

  The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof for inhibiting the growth of cancer cells, a method for the preparation thereof and a pharmaceutical composition comprising same as an active ingredient.

  本发明涉及一种新型的喹唑啉衍生物及其药学上可接受的盐，用于抑制癌细胞的生长，其制备方法以及包含其作为活性成分的制药组合物。
• Latently-curable organosilicone release coating composition
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0140530A1

  公开（公告）日：1985-05-08

  A latently-curable, organosilicone composition comprises a metal catalyzed organosilicone composition capable of undergoing hydrosilation and, as hydrosilation inhibitor, an organic monohydrogen derivative of an unsaturated aliphatic 1,4-dicarboxylic acid, i.e., maleic acid or acetylene dicarboxylic acid. The organic monohydrogen derivatives of use in this invention effectively inhibit catalyzed hydrosilation reactions at low or room temperature while allowing efficient hydrosilation reaction rates to occur at elevated temperatures. These monohydrogen derivatives perform their inhibitive function effectively at low concentration. The latently curable composition may be coated on a substrate to provide a release surface for an adjacent adhesive layer.

  一种潜伏固化的有机硅组合物包括一种可进行水合反应的金属催化有机硅组合物，以及作为水合反应抑制剂的不饱和脂肪族 1,4-二羧酸（即马来酸或乙炔二羧酸）的有机单氢衍生物。本发明中使用的有机单氢衍生物可在低温或室温下有效抑制催化的加氢反应，同时允许在高温下发生高效的加氢反应。这些单氢衍生物在低浓度下就能有效发挥其抑制功能。潜伏固化组合物可涂在基材上，为相邻的粘合剂层提供脱模表面。
• Thermoplastic propylene resin composition
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0355029A2

  公开（公告）日：1990-02-21

  A thermoplastic propylene resin composition of the present invention is obtained by blending an epoxy group containing copolymer (G) and a rubber-like material (H) and/or a modified rubber-like material (I) with a resin composition composed of a polyamide resin (F) and a polypropylene type resin (E) according to claim 1; by blending a polyamide resin (F), an epoxy group containing copolymer (G) and optionally a polypropylene (C) with a graft resin composition (J) obtained by graft copolymerizing an unsaturated carboxylic acid or a derivative thereof onto a mixture of polypropylene (C) and a rubber-like material (H) or; by blending a polyamide resin (F), an epoxy group containing copolymer (G) and optionally a polypropylene (C) with a graft resin composition (J) obtained by graft copolymerizing an unsaturated carboxylic acid or a derivative thereof and an unsaturated aromatic monomer onto a mixture of a polypropylene (C) and a rubber-like material (H). These thermoplastic propylene resin compositions can easily be processed into molded products, films or sheets by injection molding, extrusion molding or the like, giving products which have a good balance in various physical properties and a uniform and smooth appearance. They are suitable for purposes in which especially high heat resistance, impact resistance and low-temperature impact resistance are required.

  获得本发明的热塑性丙烯树脂组合物 根据权利要求1，将含环氧基共聚物(G)和类橡胶材料(H)和/或改性类橡胶材料(I)与由聚酰胺树脂(F)和聚丙烯类树脂(E)组成的树脂组合物混合； 将聚酰胺树脂(F)、含环氧基的共聚物(G)和可选的聚丙烯(C)与通过将不饱和羧酸或其衍生物接枝共聚到聚丙烯(C)和类橡胶材料(H)的混合物上而得到的接枝树脂组合物(J)混合，或； 将聚酰胺树脂 (F)、含环氧基的共聚物 (G) 和聚丙烯 (C) 与通过将不饱和羧酸或其衍生物和不饱和芳香族单体接枝共聚到聚丙烯 (C) 和类橡胶材料 (H) 混合物上得到的接枝树脂组合物 (J) 混合。 这些热塑性丙烯树脂组合物可以很容易地通过注塑成型、挤压成型或类似方法加工成模塑产品、薄膜或板材，使产品具有良好的各种物理性能平衡和均匀光滑的外观。它们适用于需要特别高的耐热性、抗冲击性和低温抗冲击性的用途。
• QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF
  申请人：Hanmi Pharm. Co., Ltd.

  公开号：EP1844022A1

  公开（公告）日：2007-10-17
• FAT-LIQUORING
  申请人：Stahl International B.V.

  公开号：EP2807278B1

  公开（公告）日：2021-12-01