2-[(2,6-Dimethylphenyl)iminomethyl]aniline | 1351061-80-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[(2,6-Dimethylphenyl)iminomethyl]aniline
• CAS: 1351061-80-7
• 化学式: C₁₅H₁₆N₂
• 分子量: 224.305
• InChiKey: NTEZDIXTJYQCEL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  38.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  三氟甲磺酸 、 2-[(2,6-Dimethylphenyl)iminomethyl]aniline 、 丙酮 以 氘代氯仿 为溶剂， 生成
  参考文献：
  名称：

  About the intermediacy of 1,2-dihydroquinazolinium salts in the Friedländer–Borsche synthesis of quinolinium salts in acidic medium

  摘要：

  Spontaneously or under various heating conditions, 2-alkyl- or 2-aryl-(iminoalkyl)benzenamines react with ketones and triflic acid (1:1:1) to give quinolinium salts. When working under milder thermal conditions, intermediate 1,2-dihydroquinazolinium derivatives can be isolated or detected in solution but decompose upon standing or heating to give the corresponding quinolinium salts. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.09.053

文献信息

• About the intermediacy of 1,2-dihydroquinazolinium salts in the Friedländer–Borsche synthesis of quinolinium salts in acidic medium
  作者：José Vicente、María Teresa Chicote、Antonio Jesús Martínez-Martínez

  DOI：10.1016/j.tetlet.2011.09.053

  日期：2011.11

  Spontaneously or under various heating conditions, 2-alkyl- or 2-aryl-(iminoalkyl)benzenamines react with ketones and triflic acid (1:1:1) to give quinolinium salts. When working under milder thermal conditions, intermediate 1,2-dihydroquinazolinium derivatives can be isolated or detected in solution but decompose upon standing or heating to give the corresponding quinolinium salts. (C) 2011 Elsevier Ltd. All rights reserved.