2-[Amino(carboxy)methyl]benzoic acid | 69613-37-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[Amino(carboxy)methyl]benzoic acid
• CAS: 69613-37-2
• 化学式: C₉H₉NO₄
• mdl: MFCD00046535
• 分子量: 195.17
• InChiKey: CDCVEEXKOMDRGS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  101
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS<br/>[FR] PUISSANTS INHIBITEURS DE PHTALATE D'ASPARTATE N-ACÉTYLTRANSFÉRASE ET INHIBITEURS SÉLECTIFS DE LA VOIE ASPARTATE
  申请人：UNIV TOLEDO

  公开号：WO2017040376A1

  公开（公告）日：2017-03-09

  Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.

  描述了作为天冬氨酸-P-半胱氨酸脱氢酶（ASADH）抑制剂化合物、天冬氨酸N-乙酰基转移酶（ANAT）抑制剂化合物或两者的邻苯二甲酸酯衍生物，以及制备这些化合物的方法和使用这些化合物的方法。
• DIMERIC IAP INHIBITORS
  申请人：STRAUB Christopher Sean

  公开号：US20110206690A1

  公开（公告）日：2011-08-25

  The present invention provides compounds of formula M-L-M′ (where M and M′ are each independently a monomeric moiety of Formula (I) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.

  本发明提供了公式M-L-M′的化合物（其中M和M′分别是公式（I）中的单体基团，L是连接物）。已发现二聚化合物在促进快速分裂细胞凋亡方面具有有效性。
• Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors
  申请人：The University of Toledo

  公开号：US10449168B2

  公开（公告）日：2019-10-22

  Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.

  描述了作为天冬氨酸-P-半醛脱氢酶（ASADH）抑制剂化合物、天冬氨酸 N-乙酰转移酶（ANAT）抑制剂化合物或两者兼具的邻苯二甲酸酯衍生物，以及制造方法和使用方法。
• POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS
  申请人：The University of Toledo

  公开号：US20180250252A1

  公开（公告）日：2018-09-06

  Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.
• US8445440B2
  申请人：——

  公开号：US8445440B2

  公开（公告）日：2013-05-21