2-ethyl-2-isopropyl-3-methyl-butyric acid amide | 7498-51-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-ethyl-2-isopropyl-3-methyl-butyric acid amide
• 英文别名: 2-Aethyl-2-isopropyl-3-methyl-buttersaeure-amid；Ethyl-diisopropylacetamide；2-ethyl-3-methyl-2-propan-2-ylbutanamide
• CAS: 7498-51-3
• 化学式: C₁₀H₂₁NO
• 分子量: 171.283
• InChiKey: PYUKMWKYZBWGKI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• Hair removal method and kit
  申请人：The Procter & Gamble Company

  公开号：EP2517692A1

  公开（公告）日：2012-10-31

  A method of removing hair from skin is provided comprising the steps of: (a) applying a protective composition to an area of skin on which unwanted hair is growing, wherein the protective composition comprises at least 75% petrolatum by weight of the protective composition, the protective composition having a cone penetration of 160 to 210; (b) applying a depilatory composition to the area of skin to which the protective composition has been applied, the depilatory composition comprising a keratin reducing agent.

  提供了一种去除皮肤毛发的方法，包括以下步骤 (a) 在长有多余毛发的皮肤区域涂抹保护性组合物，其中保护性组合物包含至少 75% 的凡士林（按重量计），保护性组合物的锥形渗透力为 160 至 210； (b) 在涂有保护性组合物的皮肤上涂抹脱毛组合物，脱毛组合物包括角蛋白还原剂。
• Compounds useful as modulators of TRPM8
  申请人：Senomyx, Inc.

  公开号：US10392371B2

  公开（公告）日：2019-08-27

  Provided herein are compounds which are useful as cooling sensation compounds.

  本文提供的化合物可用作冷感化合物。
• Cosmetic system containing an applicator and a gel composition
  申请人：L'ORÉAL

  公开号：US11364183B2

  公开（公告）日：2022-06-21

  The present invention relates to a cosmetic system comprising an applicator and a gel composition, and methods for making-up and enhancing the appearance of keratinous materials using the systems.

  本发明涉及一种由涂抹器和凝胶组合物组成的化妆品系统，以及使用该系统化妆和提升角质材料外观的方法。