2-(1'-ethoxyvinyl)-imidazolidine | 1186100-67-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 2-(1'-ethoxyvinyl)-imidazolidine
• 英文别名: 2-(1-ethoxyethenyl)imidazolidine
• CAS: 1186100-67-3
• 化学式: C₇H₁₄N₂O
• 分子量: 142.201
• InChiKey: UOTMOPBQKYKXTH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  33.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-乙氧基丙-2-烯醛 、 乙二胺 以 二甲基亚砜 为溶剂， 生成 3-(2'-aminoethylimino)-2-ethoxypropene 、 2-(1'-ethoxyvinyl)-imidazolidine
  参考文献：
  名称：

  Condensation of 2-alkoxypropenals with N,N- and N,O-1,2-binucleophiles. A route to 2-(1′-alkoxyvinyl)imidazo-lidines and -oxazolidines

  摘要：

  Condensation of 2-ethoxypropenal with diaminoethylene in different solvents (CHCl(3), MeCN, H(2)O, DMSO) at room temperature gives an equilibrium mixture (1:1-1.5) of tautomeric 2-(1'-ethoxyvinyl)-1,3-imidazolidine and 2-aminoethylimine of 2-ethoxypropenal as well as 1,2-bis(2'-ethoxypropenyl-ideneamino)ethylene. The latter is readily prepared in quantitative yield using a twofold excess of the aldehyde. (1)H NMR was used to demonstrate the effect of heating on the dynamics of the ring-chain tautomeric equilibrium. Reaction of the 2-alkoxypropenals with N-methyl- and N,N'-diphenyl-1,2-diaminoethylenes and with N-phenylaminoethanol gives only the corresponding substituted imidazolidines in 43-95% yield.

  DOI：

  10.1007/s10593-009-0213-y

文献信息

• Condensation of 2-alkoxypropenals with N,N- and N,O-1,2-binucleophiles. A route to 2-(1′-alkoxyvinyl)imidazo-lidines and -oxazolidines
  作者：N. A. Keiko、N. V. Vchislo、L. G. Stepanova、L. I. Larina、Yu. A. Chuvashev、E. A. Funtikova

  DOI：10.1007/s10593-009-0213-y

  日期：2008.12

  Condensation of 2-ethoxypropenal with diaminoethylene in different solvents (CHCl(3), MeCN, H(2)O, DMSO) at room temperature gives an equilibrium mixture (1:1-1.5) of tautomeric 2-(1'-ethoxyvinyl)-1,3-imidazolidine and 2-aminoethylimine of 2-ethoxypropenal as well as 1,2-bis(2'-ethoxypropenyl-ideneamino)ethylene. The latter is readily prepared in quantitative yield using a twofold excess of the aldehyde. (1)H NMR was used to demonstrate the effect of heating on the dynamics of the ring-chain tautomeric equilibrium. Reaction of the 2-alkoxypropenals with N-methyl- and N,N'-diphenyl-1,2-diaminoethylenes and with N-phenylaminoethanol gives only the corresponding substituted imidazolidines in 43-95% yield.