N-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]butanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]butanamide
• 化学式: C₁₀H₁₉NO₆
• 分子量: 249.26
• InChiKey: XOHMAPSXUCVOKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  119
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• FUNCTIONAL POLYMER GEL CONTAINING ORGANIC NANOTUBES AND METHOD FOR PRODUCING SAME
  申请人：SEED CO., LTD.

  公开号：US20170112761A1

  公开（公告）日：2017-04-27

  The purpose of the present invention is to provide: a functional polymer gel which is able to be practically used as an ocular lens having excellent transparency and mechanical strength by uniformly dispersing organic nanotubes in a polymer gel without the formation of agglomerates of the organic nanotubes in the case where the organic nanotubes are complexed into the polymer gel; and a method for producing this functional polymer gel. The above-mentioned purpose is achieved by: a functional polymer gel which is characterized by containing organic nanotubes and having a light transmittance of 80% or more; and a method for producing this functional polymer gel.
• [EN] BIO-INSPIRED POLYMERS FOR USE AS SYNTHETIC MUCINS<br/>[FR] POLYMÈRES BIO-INSPIRÉS DESTINÉS À ÊTRE UTILISÉS EN TANT QUE MUCINES SYNTHÉTIQUES
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2019079662A1

  公开（公告）日：2019-04-25

  Provided are glycosylated polymers that derive from carboxymethyl cellulose and may function as synthetic mucins. The carboxymethyl cellulose backbone of the polymers provide structures amenable to glycosylation by amidation of the carboxyl groups with glycosylamine moieties. The polymers can inhibit microbial virulence and may be useful in a variety of applications, such as treating microbial infections, preventing biofilm formation, and improving gastrointestinal health. Thus, provided are compositions (e.g., pharmaceutical, prebiotic, nutraceutical, food product) comprising the polymers, lubricants comprising the polymers, coatings comprising the polymers, methods of inhibiting microbial virulence, methods of inhibiting and/or preventing biofilm formation, methods of treating and/or preventing infection (e.g., bacterial, protozoan, or fungal infection). Also provided are methods of preparing the polymers described herein.