L-天门冬氨酸锌

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: L-天门冬氨酸锌
• 英文名称: zinc;(2S)-2-amino-4-hydroxy-4-oxobutanoate
• 化学式: C8H12N2O8Zn
• 分子量: 329.6
• InChiKey: POEVDIARYKIEGF-CEOVSRFSSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.93
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  207
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
  申请人：SILL Kevin N.

  公开号：US20080274173A1

  公开（公告）日：2008-11-06

  The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.

  本发明涉及聚合物化学领域，更具体地说是涉及多嵌段共聚物以及包含该共聚物的胶束。
• Sun protection compositions comprising semi-crystalline polymers and hollow latex particles
  申请人：Candau Didier

  公开号：US20090041691A1

  公开（公告）日：2009-02-12

  Topically applicable cosmetic/dermatological UV protection compositions having enhanced SPF contain at least one organic UV screening agent and/or at least one inorganic screening agent, such compositions also containing at least the following constituents (A) and (B): A) a semi-crystalline polymer which is solid at ambient temperature and has a melting point of greater than or equal to 30° C., containing a) a polymeric backbone and b) at least one crystallizable organic side chain and/or one crystallizable organic block forming part of the backbone of this said polymer, said polymer having a number-average molecular mass Mn of greater than or equal to 1,000, and B) hollow latex particles having a particle size ranging from 150 to 380 nm, formulated into a topically applicable, physiologically acceptable medium therefor.

  具有增强SPF的适用于化妆品/皮肤科的防紫外线保护组合物至少包含一种有机紫外线过滤剂和/或至少一种无机过滤剂，此类组合物还至少包含以下成分（A）和（B）： A）半结晶聚合物，室温下为固体，熔点大于或等于30°C，包含a）聚合骨架和b）至少一种可结晶有机侧链和/或作为该聚合物骨架一部分的可结晶有机块，该聚合物具有大于或等于1,000的数均分子质量Mn，以及 B）中空乳胶颗粒，粒径范围为150至380纳米，配制成适用于局部使用的、生理上可接受的介质。
• Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor
  申请人：Lucet-Levannier Karine

  公开号：US20100086502A1

  公开（公告）日：2010-04-08

  Cosmetic/sunscreen compositions contain a combination of at least one dibenzoylmethane sunscreen compound and a photostabilizing amount of at least one dithiolane compound of formula (I) below:

  化妆品/防晒霜组合物含有至少一种二苯甲酮类防晒剂化合物和至少一种式（I）所示的二硫杂环化合物的光稳定量。
• Artificially coloring the skin with a carotene compound, a xanthophyll compound and a lipophilic green dye composition
  申请人：Cassin Guillaume

  公开号：US20100150853A1

  公开（公告）日：2010-06-17

  A method for artificially coloring the skin entails topical application thereon of a composition containing, formulated into a physiologically acceptable medium: a) at least one compound of the carotene type, b) at least one compound of the xanthophyll type, c) at least one lipophilic green dye; the composition advantageously includes a mixture of dyes including: a) at least one compound of the carotene type, b) at least astaxanthin, c) at least one lipophilic green dye.

  一种人工着色皮肤的方法包括在皮肤上局部涂抹一种含有以下成分的组合物，配制成生理可接受的介质：a) 至少一种类胡萝卜素的化合物，b) 至少一种黄色素类的化合物，c) 至少一种亲脂性绿色染料；该组合物优选包括一种混合染料，其中包括：a) 至少一种类胡萝卜素的化合物，b) 至少一种虾青素，c) 至少一种亲脂性绿色染料。
• [EN] RUBIDIUM AND/OR ZINC COMPOUNDS FOR TREATING PARKINSON'S AND OTHER NEURODEGENERATIVE DISEASES<br/>[FR] COMPOSÉS DE RUBIDIUM ET/OU DE ZINC POUR LE TRAITEMENT DE LA MALADIE DE PARKINSON ET D'AUTRES MALADIES NEURODÉGÉNÉRATIVES
  申请人：VECTOR VITALE IP LLC

  公开号：WO2021071499A1

  公开（公告）日：2021-04-15

  Compositions that comprise salts, compounds and complexes of 64Zn-enriched zinc, such as 64Zn-enriched zinc aspartate, and further optionally include 85Rb-enriched rubidium salt compounds of general formula (1), below, wherein each of R1 through R14 is independently selected from H, OH, F, C1, Br, I, C1-C6 alkyl, C1-C6 alkoxy, and NO2, such as the compound of Formula 1 in which R3 is CH3 and all other R groups are H for use to treat a neurodegenerative disease (NDD), such as Parkinson's disease (PD). Methods that entail administering such compositions to treat an NDD, such as PD, optionally in combination with any other treatment for an NDD such as for PD.

  含有盐、化合物和富集64Zn的锌的化合物，例如富集64Zn的天冬酸锌，以及进一步可能包括通式（1）所示的富集85Rb的铷盐化合物，其中R1至R14中的每个均独立选择自H、OH、F、C1、Br、I、C1-C6烷基、C1-C6烷氧基和NO2，例如通式1中R3为CH3且所有其他R基为H的化合物，用于治疗神经退行性疾病（NDD），如帕金森病（PD）。方法包括向患有NDD的患者施用这种组合物以治疗NDD，如PD，可以选择与其他用于治疗NDD（如PD）的任何其他治疗方法结合使用。