L-苯丙氨酸,N-(2-甲基-1-羰基-2-丙烯基)- | 16951-81-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: L-苯丙氨酸,N-(2-甲基-1-羰基-2-丙烯基)-
• 中文别名: L-苯丙氨酸,N-(2-甲基-1-羰基-2-丙烯基)-
• 英文名称: N-(2-Methylacryloyl)-L-phenylalanine
• 英文别名: (2S)-2-(2-methylprop-2-enoylamino)-3-phenylpropanoic acid
• CAS: 16951-81-8
• 化学式: C₁₃H₁₅NO₃
• 分子量: 233.26
• InChiKey: HIZGPVWGTSAEKJ-NSHDSACASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• DRUG DELIVERY VEHICLES, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF
  申请人：Thayumanavan Sankaran

  公开号：US20110200675A1

  公开（公告）日：2011-08-18

  Drug delivery vehicles that release one or more drugs, e.g., an opioid antagonist and/or an opioid, in response to changes in the chemistry of body fluids, specifically in response to changes in the partial pressure of CO 2 in the environment of the hydrogel are described. The drug delivery vehicles include hydrogels that swell or shrink in response to changes in the partial pressure of CO 2 in their environment, thus regulating release of an entrapped drug.

  本文描述了一种药物递送载体，该载体可以在体液化学变化，特别是在二氧化碳分压环境变化的情况下释放一个或多个药物，例如阿片拮抗剂和/或阿片类药物。这些药物递送载体包括水凝胶，水凝胶可以在其环境中二氧化碳分压的变化下膨胀或收缩，从而调节所包含药物的释放。
• ADHESIVE COMPOSITION FOR DENTAL USE
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20210145701A1

  公开（公告）日：2021-05-20

  The present invention provides a dental adhesive composition that, even after photocuring with a high-output LED irradiator, shows high bond strength not only for dentin untreated by phosphoric acid etching but also for dentin treated by phosphoric acid etching. The present invention relates to a dental adhesive composition comprising a phosphoric acid group-containing polymerizable monomer (A), the phosphoric acid group-containing polymerizable monomer (A) comprising: a dihydrogen phosphate monoester group-containing polymerizable monomer (A-1) represented by general formula (1); a hydrogen phosphate diester group-containing polymerizable monomer (A-2) represented by general formula (2); and a phosphoric acid tetraester group-containing polymerizable monomer (A-3) represented by general formula (3).

  本发明提供了一种牙科粘接剂组合物，即使经过高输出LED辐射器的光固化，也能显示出高的粘接强度，不仅适用于未经过磷酸蚀刻处理的牙本质，还适用于经过磷酸蚀刻处理的牙本质。本发明涉及一种牙科粘接剂组合物，包括含磷酸基可聚合单体（A），其中磷酸基可聚合单体（A）包括：一种由通式（1）表示的二氢磷酸单酯基可聚合单体（A-1）；一种由通式（2）表示的氢磷酸双酯基可聚合单体（A-2）；以及一种由通式（3）表示的磷酸四酯基可聚合单体（A-3）。
• Photopolymerization initiator and photopolymerizable composition
  申请人：Tokuyama Corporation

  公开号：EP1431315A2

  公开（公告）日：2004-06-23

  A photopolymerization initiator comprising (A) a photo acid-generating compound such as diaryliodonium salt (e.g., diphenyl iodonium, bis(p-chlorophenyl)iodonium, etc.,), (B) a photo oxidation radical-generating compound such as diarylketone compound, α-diketone compound or ketocoumarin compound, and (C) a fused polycyclic aromatic compound such as 1,4-dimethylnaphthalene, 1-methylanthracene, 9-methylanthracene, 9,10-dimethylanthracene or 9,10-diethylanthracene. The photopolymerization initiator makes it possible to efficiently polymerize the cationically polymerizable monomer by the irradiation with visible light.

  一种光聚合引发剂，包括(A) 光酸生成化合物，如二芳基碘鎓盐（如二苯基碘鎓、双（对氯苯基）碘鎓等），(B) 光氧化自由基生成化合物，如二芳基酮化合物、α-二酮化合物或酮香豆素化合物，以及(C) 熔融多环芳基化合物、(C) 熔融多环芳烃化合物，如 1,4-二甲基萘、1-甲基蒽、9-甲基蒽、9,10-二甲基蒽或 9,10-二乙基蒽。光聚合引发剂可以使阳离子可聚合单体在可见光的照射下有效聚合。
• ADHESIVES FOR DENTAL USE
  申请人：TOKUYAMA CORPORATION

  公开号：EP1459726A1

  公开（公告）日：2004-09-22

  A dental adhesive containing an acidic group-containing radically polymerizable monomer, a non-acidic radically polymerizable monomer, a chemical polymerization initiator and a filler, as well as a 2,4-diphenyl-4-methyl-1-pentene. When the dental adhesive is used for adhering a crown restorative to the tooth, an excess of cement swelling from the surface of adhesion can be favorably removed, the curing time can be suitably adjusted without decreasing the strength of adhesion to the tooth, and a change in the color tone of the cured body can be effectively suppressed.

  一种牙科粘合剂，含有含酸性基团的可辐射聚合单体、非酸性可辐射聚合单体、化学聚合引发剂和填料，以及 2,4-二苯基-4-甲基-1-戊烯。当牙科粘合剂用于将牙冠修复体粘合到牙齿上时，可以有效地去除粘合表面过量的水泥膨胀，适当调整固化时间而不会降低与牙齿的粘合强度，并能有效抑制固化体色调的变化。
• POLYMERIZABLE MONOMER-CONTAINING COMPOSITION
  申请人：Kuraray Medical Inc.

  公开号：EP2112177A1

  公开（公告）日：2009-10-28

  The present invention provides a composition suitable for a dental composition. The present invention is a composition containing: a polymerizable monomer (A) having an unconjugated carbon chain with at least four carbon atoms bonded continuously, at least two polymerizable groups, and at least two hydroxyl groups; and a water (B). The composition contains 6 to 2000 parts by weight of the water (B) with respect to 100 parts by weight of the whole amount of polymerizable monomer components. When suitable components are added to this composition, the resultant composition can be used suitably for dental materials such as a primer, bonding material, composite resin, and cement.

  本发明提供了一种适用于牙科组合物的组合物。本发明的组合物含有：可聚合单体（A），其具有至少四个碳原子连续键合的非共轭碳链、至少两个可聚合基团和至少两个羟基；以及水（B）。相对于 100 重量份的可聚合单体成分总量，该组合物含有 6 至 2000 重量份的水（B）。在该组合物中加入适当的成分后，所得到的组合物可用于牙科材料，如底漆、粘合材料、复合树脂和水泥。