Icosa-5,8,11,14-tetraen-1-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Icosa-5,8,11,14-tetraen-1-ol
• 化学式: C₂₀H₃₄O
• 分子量: 290.5
• InChiKey: NYBCZSBDKXGAGM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  21
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• PROCESS FOR PREPARING AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION IN THE PRESENCE OF A COMPLEX CATALYST COMPRISING IRIDIUM AND AN AMINO ACID
  申请人：BASF SE

  公开号：US20140046054A1

  公开（公告）日：2014-02-13

  The invention relates to a process for preparing amines (A) by alcohol amination of alcohols (Al) by means of an aminating agent (Am) with elimination of water, wherein the alcohol amination is carried out in the presence of a complex catalyst comprising iridium and an amino acid.

  该发明涉及一种通过醇胺化剂（Am）在消除水的情况下，通过醇（Al）的醇胺化制备胺（A）的过程，其中醇胺化在铱和氨基酸组成的复合催化剂存在下进行。
• Method for producing poly-alpha-olefins
  申请人：——

  公开号：US20040267073A1

  公开（公告）日：2004-12-30

  Process for producing poly-&agr;-olefins are described wherein the processes comprise: (a) providing a primary alcohol; and (b) polymerizing the primary alcohol in the presence of an acidic alumino layer silicate to form a poly-&agr;-olefin. Water formed during the polymerization can be removed, optionally during the polymerization, and subsequent hydrogenation may be performed.

  制备聚α-烯烃的方法描述如下，该方法包括：(a) 提供一种伯醇；(b) 在酸性硅铝层状硅酸盐的存在下聚合该伯醇以形成聚α-烯烃。聚合过程中产生的水可以被移除，可选地在聚合过程中移除，并且随后可以进行氢化。
• Process for the Synthesis of Long-Chain Fatty Acids
  申请人：Fauq Abdul H.

  公开号：US20110105781A1

  公开（公告）日：2011-05-05

  This invention relates to processes for preparing long-chain fatty acids of Formula I: and salts thereof, as well as intermediates for the processes, wherein L 1 and L 2 are described herein.

  本发明涉及制备式I的长链脂肪酸及其盐的方法，以及用于该方法的中间体，其中L1和L2如本文所述。
• Anti-cancer nitro- and thia-fatty acids
  申请人：——

  公开号：US20030078299A1

  公开（公告）日：2003-04-24

  The present invention relates to pharmaceutical compositions comprising, as an anti-cancer agent: (a) one or more compounds having the formula NO 2 —A—B, 1 wherein A is a saturated or unsaturated hydrocarbon chain of 14-26 double bonds, and B is (CH 2 ) m (COOH) n in which n is a integer from 0 to 2 and m is an integer from 0 to 2; or a derivative thereof in which the hydrocarbon chain has one or more than one substitution selected from the group consisting of hydroxy, hydroperoxy, epoxy and peroxy; (b) one or more compounds selected from polyunsaturated fatty acids (PUFA's) having a 16 to 26 carbon atom chain and 3 to 16 double bonds, and wherein the PUFA is covalently coupled at the carboxylic acid group to an amino acid selected from glycine and aspartic acid; (c) one or more compounds selected from unsaturated fatty acids having an 18 to 25 carbon atom chain and 1 to 6 double bonds and wherein the fatty acid has one or two &bgr;-oxa, &ggr;-oxa, &bgr;-thia, &ggr;-thia substitutions: or (d) one or more compounds having formula (I) wherein A′ is a saturated or unsaturated hydrocarbon chain of 9-26 carbon atoms, X is oxygen or is absent and B′ is (CH 2 ) J (COOH) k in which j is an integer from 1 to 3 and K is 0 or 1; or a derivative thereof in which the hydrocarbon chain has one or more than one substitution selected from the group consisting of hydroxy, hydroperoxy, epoxy and peroxy; and a pharmaceutically acceptable carrier or diluent.

  本发明涉及制药组合物，包括作为抗癌剂的：(a) 一个或多个具有式NO2—A—B,1的化合物，其中A是14-26个双键的饱和或不饱和碳氢链，B是(CH2)m(COOH)n，其中n是0到2的整数，m是0到2的整数；或其衍生物，其中碳氢链具有羟基、过氧化氢基、环氧基和过氧基中的一种或多种取代；(b) 一种或多种选择自具有16到26个碳原子链和3到16个双键的多不饱和脂肪酸（PUFA），其中PUFA在羧酸基上与选择自甘氨酸和天冬氨酸的氨基酸共价耦合；(c) 一种或多种选择自具有18到25个碳原子链和1到6个双键的不饱和脂肪酸，其中脂肪酸具有一或两个β-氧杂、γ-氧杂、β-硫杂、γ-硫杂取代；或(d) 公式(I)中A′是9-26个碳原子的饱和或不饱和碳氢链，X是氧或不存在，B′是(CH2)J(COOH)k，其中j是1到3的整数，k是0或1；或其衍生物，其中碳氢链具有羟基、过氧化氢基、环氧基和过氧基中的一种或多种取代；以及药学上可接受的载体或稀释剂。
• PROCESS FOR DYEING HAIR
  申请人：Henkel AG & Co. KGaA

  公开号：US20200397684A1

  公开（公告）日：2020-12-24

  The subject of the present disclosure is a process for dyeing human hair, in which a pretreatment agent (A) which contains at least one organic silicon compound of the formula (I) and/or (II) and contains no direct dyes and no pigments, and a colorant (B) which contains at least one organic silicon compound of the formula (I) and/or (II) and further contains at least one colorant compound from the group of direct dyes and/or pigments, can be applied to the hair, wherein the organic silicon compounds of formulae (I) and (II) are defined as follows R 1 R 2 N-L-Si(OR 3 ) a (R 4 ) b (I), (R 5 O) c (R 6 ) d Si-(A) e -[NR 7 -(A′)] f —[O-(A″)] g -[NR 8 -(A′″)] h —Si(R 6 ′) d′ (OR 5 ′) c′ (II).

  本公开的主题是一种染色人类头发的过程，其中可以将含有至少一种有机硅化合物公式(I)和/或(II)且不含有直接染料和颜料的预处理剂(A)，和含有至少一种有机硅化合物公式(I)和/或(II)且进一步含有直接染料和/或颜料化合物群中的至少一种颜料化合物的染料剂(B)应用于头发上。其中，公式(I)和(II)的有机硅化合物定义如下：R1R2N-L-Si(OR3)a(R4)b(I)，(R5O)c(R6)dSi-(A)e-[NR7-(A′)]f—[O-(A″)]g-[NR8-(A′″)]h—Si(R6′)d′(OR5′)c′(II)。