(E)-2-Phenyl-1,3-bis(trimethylsilyl)-2-phenylprop-1-ene | 98064-18-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-2-Phenyl-1,3-bis(trimethylsilyl)-2-phenylprop-1-ene
• 英文别名: (E)-1,3-bis(trimethylsilyl)-2-phenyl-1-propene；trimethyl-[(E)-2-phenyl-3-trimethylsilylprop-1-enyl]silane
• CAS: 98064-18-7
• 化学式: C₁₅H₂₆Si₂
• 分子量: 262.542
• InChiKey: UROLIWZOSMHBMO-QINSGFPZSA-N

物化性质

• 沸点：
  290.6±29.0 °C(Predicted)
• 密度：
  0.862±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.29
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-苯基-1,3-二噻烷 在 bis(triphenylphosphine)nickel(II) chloride 正丁基锂 作用下， 以 四氢呋喃 、 苯 为溶剂， 反应 0.5h， 生成 (E)-2-Phenyl-1,3-bis(trimethylsilyl)-2-phenylprop-1-ene
  参考文献：
  名称：

  Tzeng, Yih-Ling; Cheng, Wen-Lung; Luh, Tien-Yau, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1995, vol. 50, # 3, p. 385 - 393

  摘要：

  DOI：

文献信息

• Nickel-catalysed alkylative alkenation of orthothioesters with grignard reagents; a convenient procedure for introducing the isopropenyl group. Synthesis of substituted 1,3-(bis-trimethylsilyl)propenes
  作者：Yih-Ling Tzeng、Tien-Yau Luh、Jim-Min Fang

  DOI：10.1039/c39900000399

  日期：——

  Nickel-catalysed coupling of orthothioesters with MeMgl furnishes a general method for introducing the Isopropenyl group; the application of this reaction to the synthesis of 1,3-(bis-trimethylsilyl)propenes is presented.

  镍催化的原硫酸酯与MeMgl的偶联提供了引入异丙烯基的一般方法；介绍了该反应在1,3-（双-三甲基甲硅烷基）丙烯合成中的应用。
• Pd-Catalyzed Coupling Reaction of Acetylenes, Iodotrimethylsilane, and Organozinc Reagents for the Stereoselective Synthesis of Vinylsilanes
  作者：Naoto Chatani、Nobuyoshi Amishiro、Takaya Morii、Toshiaki Yamashita、Shinji Murai

  DOI：10.1021/jo00111a048

  日期：1995.3

  The reaction of terminal acetylenes with Me(3)SiI (1) and organozinc reagents in the presence of Pd(PPh(3))(4) results in addition of the trimethylsilyl group of 1 and an alkyl group of the organozinc reagent to the acetylenes. In all cases the trimethylsilyl group adds to the terminal carbon of the acetylenes. Both aromatic and aliphatic terminal acetylenes undergo the coupling reaction with high regio- and stereoselectivities. The yield and stereoselectivity are relatively sensitive to the nature of the organozinc reagent used. The reaction of phenylacetylene (2) using Bu(2)Zn gives the corresponding coupling product in high yield with high stereoselectivity (>98%). In contrast, the use of BuZnI results in 92% stereoselectivity. The stereoselectivity for the reaction using (Me(3)-SiCH2)(2)Zn is lower than those for Me(2)Zn, Et(2)Zn, and Bu(2)Zn. For organozinc reagents, alkylzinc works well while phenyl-, ethynyl-, and allylzinc do not. The reaction using Me(3)SiCl, Me(3)SiBr, Me(3)SiSPh, Me(3)SiSePh, and Me(3)SiOTf in place of 1 does not proceed. The reaction with Me(3)SiMe(2)-SiI and Me(3)SiMe(2)SiMe(2)SiI in place of 1 gives the corresponding vinyldisilane and -trisilane, respectively.
• The effect of added silver nitrate on the palladium-catalyzed arylation of allyltrimethylsilanes
  作者：Kostas Karabelas、Christer Westerlund、Anders Hallberg

  DOI：10.1021/jo00220a042

  日期：1985.10
• Chatani Naoto, Amishiro Nobuyoshi, Morii Takaya, Yamashita Toshiaki, Mura+, J. Org. Chem, 60 (1995) N 6, S 1834-1840
  作者：Chatani Naoto, Amishiro Nobuyoshi, Morii Takaya, Yamashita Toshiaki, Mura+

  DOI：——

  日期：——