Triacetoxy-methan | 26448-69-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Triacetoxy-methan
• 英文别名: Triacetoxymethane；diacetyloxymethyl acetate
• CAS: 26448-69-1
• 化学式: C₇H₁₀O₆
• 分子量: 190.153
• InChiKey: VWAAXABRJDIYOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  Orthoameisensaeure-triisopropenylester 生成 Triacetoxy-methan
  参考文献：
  名称：

  Stetter,H.; Reske,E., Chemische Berichte, 1970, vol. 103, p. 639 - 642

  摘要：

  DOI：

文献信息

• APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
  申请人：Bruncko Milan

  公开号：US20110124628A1

  公开（公告）日：2011-05-26

  Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

  本发明涉及一种抑制抗凋亡Bcl-2蛋白活性的化合物，含有该化合物的组合物以及治疗表达抗凋亡Bcl-2蛋白的疾病的方法。
• MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
  申请人：Constellation Pharmaceuticals, Inc.

  公开号：US20150259351A1

  公开（公告）日：2015-09-17

  Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

  本文提供了调节甲基修饰酶的代理、组合物和使用方法。
• TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20150291655A1

  公开（公告）日：2015-10-15

  Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: with X selected from C 4-8 cycloalkyl, C 4-8 cycloalkenyl, C 4-9 spirocycloalkyl, C 4-9 spirocycloalkenyl, C 4-8 oxacycloalkyl, C 4-8 dioxacycloalkyl, C 6-8 oxacycloalkenyl, C 6-8 dioxacycloalkenyl, C 6 cyclodialkenyl, C 6 oxacyclodialkenyl, C 6-9 oxaspirocycloalkyl and C 6-9 oxaspirocycloalkenyl ring, such that X is substituted with A, wherein A is —C 1-6 alkyl-halo. These compounds are useful for the treatment of HIV and AIDS.

  本文提供了具有药物和生物影响特性的化合物、它们的制药组合物和使用方法。特别地，提供了具有独特的抗病毒活性的三萜类化合物，作为HIV成熟抑制剂，如公式I所示的化合物：其中X选择自C4-8环烷基、C4-8环烯基、C4-9螺环烷基、C4-9螺环烯基、C4-8氧杂环烷基、C4-8二氧杂环烷基、C6-8氧杂环烯基、C6-8二氧杂环烯基、C6环二烯基、C6氧杂环二烯基、C6-9氧杂螺环烷基和C6-9氧杂螺环烯基环，使得X被A取代，其中A为—C1-6烷基-卤素。这些化合物对于治疗HIV和艾滋病有用。
• Silicon nanocrystals with functional surfaces
  申请人：Technische Universität München

  公开号：EP2980018A1

  公开（公告）日：2016-02-03

  Functionalized silicon nanocrystals, a method for their preparation and uses thereof are described.

  介绍了功能化硅纳米晶体、其制备方法及其用途。
• Modulators of methyl modifying enzymes, compositions and uses thereof
  申请人：Constellation Pharmaceuticals, Inc.

  公开号：US10016405B2

  公开（公告）日：2018-07-10

  Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

  本文提供了调节甲基修饰酶的制剂、组合物及其用途。