n-Ethyl-n-(3-sulfopropyl) m-anisidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: n-Ethyl-n-(3-sulfopropyl) m-anisidine
• 英文别名: 3-(N-ethyl-3-methoxyanilino)propane-1-sulfonic acid
• 化学式: C₁₂H₁₉NO₄S
• 分子量: 273.35
• InChiKey: STBWJPWQQLXSCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  75.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions
  申请人：Trieselmann Thomas

  公开号：US20070112033A1

  公开（公告）日：2007-05-17

  The present invention relates to new beta-agonists of general formula (I) wherein the groups R 1 to R 4 have the meanings given in ths claims and specification, the tautomers, racemates, enantiomers, diastereomers, solvates, hydrates, mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, methods of preparing these compounds and their use as pharmaceutical compositions.

  本发明涉及一般式(I)的新β-激动剂，其中基团R1至R4具有权利要求和说明书中给定的含义，其互变异构体、外消旋体、对映体、非对映体、溶剂合物、水合物、它们的混合物，它们的前体药物及其盐，特别是其与无机或有机酸或碱的生理上可接受的盐，以及制备这些化合物的方法和它们作为药物组合物的用途。
• Determination method of biological component and reagent kit used therefor
  申请人：——

  公开号：US20020119507A1

  公开（公告）日：2002-08-29

  The present invention provides novel glutathione-dependent formaldehyde dehydrogenase that makes possible quantitative measurement of formaldehyde by cycling reaction, and a determination method of formaldehyde and biological components, such as creatinine, creatine, homocysteine and the like, which produces formaldehyde as a reaction intermediate. In addition, the present invention provides a reagent kit for the above-mentioned determination method. The present invention provides a novel determination method of a homocysteine using transferase utilizing homocysteine and other compound as a pair of substrates. Particularly, the present invention provides a determination method of homocysteine which includes bringing betaine-homocysteine methyltransferase and dimethylglycine oxidase into contact with a sample and measuring produced hydrogen peroxide or formaldehyde. Moreover, the present invention provides novel dimethylglycine oxidase stable to thiol compound, which is suitably used for the measurement. The present invention provides a reagent kit used for any of the above-mentioned determination methods of homocysteines.

  本发明提供了一种新型的谷胱甘肽依赖性甲醛脱氢酶，它使得通过循环反应定量测量甲醛成为可能，并提供了一种测定甲醛和生物成分（如肌酐、肌酸、同型半胱氨酸等）的方法，该方法产生甲醛作为反应中间体。此外，本发明还提供了用于上述测定方法的试剂盒。本发明提供了一种新型的利用同型半胱氨酸和其他化合物作为一对底物的转移酶测定同型半胱氨酸的方法。特别是，本发明提供了一种同型半胱氨酸的测定方法，其中包括将甜菜碱-同型半胱氨酸甲基转移酶和二甲基甘氨酸氧化酶与样品接触，并测量产生的过氧化氢或甲醛。此外，本发明还提供了一种对巯基化合物稳定的新型二甲基甘氨酸氧化酶，适用于测量。本发明提供了用于上述同型半胱氨酸测定方法的试剂盒。
• OXIDATIVE CHROMOGENIC COMPOUND OR SALT THEREOF AND PRODUCTION METHOD THEREOF, AND REAGENT COMPOSITION AND TEST INSTRUMENT USING THE SAME
  申请人：Kawanishi Tetsuro

  公开号：US20100062464A1

  公开（公告）日：2010-03-11

  It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): wherein R 1 and R 2 are each independently a linear or branched alkyl group having 1 to 5 carbon atoms; R 3 , R 4 , R 5 , R 6 and R 7 are each independently a hydrogen atom, a carboxyl group or a sulfonic acid group, or salt thereof, provided that at least one of R 3 to R 7 is a carboxyl group or a sulfonic acid group, or salt thereof, and the others are hydrogen atoms, and the production method thereof, and the reagent composition and test instrument using the same.

  本发明的目的是提供一种快速、高精度和高灵敏度测量各种成分浓度的手段。本发明提供了一种氧化性显色化合物或其盐，其化学式如下（1）：其中R1和R2分别是具有1至5个碳原子的线性或支链烷基；R3、R4、R5、R6和R7分别是氢原子、羧基或磺酸基，或其盐，但至少其中之一是羧基或磺酸基，或其盐，其余为氢原子，以及其生产方法、试剂组成和使用该试剂组成的测试仪器。
• Verfahren und Reagenz zum Nachweis von Schädigungen bzw. Erkrankungen des Herzens
  申请人：BOEHRINGER MANNHEIM GMBH

  公开号：EP0243901A1

  公开（公告）日：1987-11-04

  zum spezifischen und frühen Nachweis von Schädigungen bzw. Erkrankungen des Herzens, insbesondere von akutem Herzinfarkt, wird ein niedermolekularer Metabolit, beispielsweise Creatin oder Creatinphosphat, 2 - 8 Stunden nach dem Auftreten der ersten Symptome bestimmt. Zur Bestimmung des hierbei enzymatisch freigesetzten H202 wird ein Reagenz, das neben einem Elektronen- oder Radikal-Akzeptor ein Anilinderivat als Wasserstoff-Donor beinhaltet, verwendet.

  为了特异性地及早检测心脏损伤或疾病，特别是急性心肌梗塞，可在首发症状出现 2-8 小时后测定低分子量代谢物，如肌酸或磷酸肌酸。 除电子或自由基受体外，还可使用含有苯胺衍生物作为氢供体的试剂来测定在此过程中酶解释放的 H202。
• Pyruvate oxidase having high thermal stability, analytical methods using it and analytical reagents containing it
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP0257986A2

  公开（公告）日：1988-03-02

  A pyruvate oxidase having high thermal stability, being stable at a pH of 7.0 for 10 minutes at a temperature of up to 45°C, can be obtained by culturing a strain of bacteria of the genus Lactobacillus which has pyruvate oxidase activity, such as Lactobacillus sp. TE-6103 (FERM BP-1419). This pyruvate oxidase can be used in analytical methods requiring such an enzyme, for which purpose it can form part of an analytical reagent for use in such a method.

  通过培养具有丙酮酸氧化酶活性的乳酸杆菌属细菌菌株，如 Lactobacillus sp. TE-6103 (FERM BP-1419)，可以获得一种具有高热稳定性的丙酮酸氧化酶，它在 pH 值为 7.0、温度高达 45℃的条件下稳定 10 分钟。这种丙酮酸氧化酶可用于需要这种酶的分析方法中，为此，它可以成为用于这种方法的分析试剂的一部分。