3-[(2S)-morpholin-2-yl]propan-1-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 3-[(2S)-morpholin-2-yl]propan-1-amine
• 化学式: C₇H₁₆N₂O
• 分子量: 144.21
• InChiKey: OETNGFVFDOSLHW-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Pyridyl derivatives as bromodomain inhibitors
  申请人：GlaxoSmithKline Intellectual Property (No. 2) Limited

  公开号：US10934272B2

  公开（公告）日：2021-03-02

  The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

  本发明涉及式（I）化合物及其盐类、含有此类化合物的药物组合物以及它们在治疗中的用途。
• PYRIDYL DERIVATIVES AS BROMODOMAIN INHIBITORS
  申请人：GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED

  公开号：US20190119248A1

  公开（公告）日：2019-04-25

  The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
• BENZO[B]FURANS AS BROMODOMAIN INHIBITORS
  申请人：GlaxoSmithKline Intellectual Property (No.2) Limited

  公开号：US20190151279A1

  公开（公告）日：2019-05-23

  The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.