2,3,6-tri-O-benzyl-4-deoxy-4-(1'H-tetrazole)-α-D-galactopyranosyl 2,3,6-tri-O-benzyl-4-deoxy-4-(2'H-tetrazole)-α-D-galactopyranoside

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3,6-tri-O-benzyl-4-deoxy-4-(1'H-tetrazole)-α-D-galactopyranosyl 2,3,6-tri-O-benzyl-4-deoxy-4-(2'H-tetrazole)-α-D-galactopyranoside
• 英文别名: 1-[(2S,3S,4S,5R,6R)-6-[(2R,3R,4S,5S,6S)-3,4-bis(phenylmethoxy)-6-(phenylmethoxymethyl)-5-(tetrazol-2-yl)oxan-2-yl]oxy-4,5-bis(phenylmethoxy)-2-(phenylmethoxymethyl)oxan-3-yl]tetrazole
• 化学式: C₅₆H₅₈N₈O₉
• 分子量: 987.125
• InChiKey: XOKJXJVVSUBSFS-PHTLTCMDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  73
• 可旋转键数：
  24
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  170
• 氢给体数：
  0
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  2,3,6-tri-O-benzyl-α-D-glucopyranosyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside 在 吡啶 、 potassium carbonate 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 反应 45.0h， 生成 2,3,6-tri-O-benzyl-4-deoxy-4-(1'H-tetrazole)-α-D-galactopyranosyl 2,3,6-tri-O-benzyl-4-deoxy-4-(2'H-tetrazole)-α-D-galactopyranoside
  参考文献：
  名称：

  Synthesis of New Tetrazole Derivatives of α,α‐Trehalose

  摘要：

  Five new nitrogen heterocycles, mono- and disubstituted tetrazoles with potential synthetic and pharmacological interest, were synthesized from a, alpha-trehalose via the alkylation of commercial tetrazoles. This method appears to have broad scope with respect to the variations at positions 1 and 2 of tetrazole.

  DOI：

  10.1080/00397910701543010

文献信息

• Synthesis of New Tetrazole Derivatives of α,α‐Trehalose
  作者：Leandro J. dos Santos、Mara R. C. Couri、Inácio Luduvico、Rosemeire B. Alves、Maria A. F. Prado、Rossimiriam P. Freitas Gil

  DOI：10.1080/00397910701543010

  日期：2007.9.1

  Five new nitrogen heterocycles, mono- and disubstituted tetrazoles with potential synthetic and pharmacological interest, were synthesized from a, alpha-trehalose via the alkylation of commercial tetrazoles. This method appears to have broad scope with respect to the variations at positions 1 and 2 of tetrazole.