N,N-二丁基-1,3-丙烷二胺 | 1187-33-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N,N-二丁基-1,3-丙烷二胺
• 英文名称: Ν,Ν-dibutyl-propionamide
• 英文别名: N,N-dibutyl-propionamide；N,N-Dibutyl-propionamid；Propionsaeure-dibutylamid；Propionsaeure-di-n-butylamid；N,N-Di-n-butyl-propionamid；N,N-Dibutyl-propionamid；Propanamide, N,N-dibutyl-；N,N-dibutylpropanamide
• CAS: 1187-33-3
• 化学式: C₁₁H₂₃NO
• mdl: MFCD01338118
• 分子量: 185.31
• InChiKey: XAROAZKXMDRYAF-UHFFFAOYSA-N

物化性质

• 沸点：
  319.55°C (rough estimate)
• 密度：
  0.9315 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2924199090

反应信息

• 作为反应物：
  描述：

  N,N-二丁基-1,3-丙烷二胺 在 劳森试剂 作用下， 生成 N,N-Dibutylthiopropionamid
  参考文献：
  名称：

  Fritz,H. et al., Bulletin des Societes Chimiques Belges, 1978, vol. 87, p. 525 - 534

  摘要：

  DOI：
• 作为产物：
  描述：

  丙酸 在 四氯化硅 、 苯 作用下， 生成 N,N-二丁基-1,3-丙烷二胺
  参考文献：
  名称：

  Jur'ew et al., Zhurnal Obshchei Khimii, 1959, vol. 29, p. 2594,2595, 2596; engl. Ausg. S. 2557, 2558

  摘要：

  DOI：

文献信息

• Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties
  作者：Bruno S. Huegi、Anton M. Ebnoether、Erwin Rissi、Fulvio Gadient、Daniel Hauser、Dietmar Roemer、Heinz H. Buescher、Trevor J. Petcher

  DOI：10.1021/jm00355a010

  日期：1983.1

  activity. Several of these analogues show analgesic potency comparable to morphine in the mouse writhing and tail-flick tests. A number of compounds exhibit high affinity for [3H]naloxone binding sites in rat brain membranes. Among the most potent derivatives are compounds 15 and 48. Although opiate-like, attempts to modify this activity with various substituents have failed to produce antagonistic properties

  已经合成了一系列的4，4-二取代的哌啶并评估了其止痛活性。这些类似物中的几种在小鼠扭动和甩尾试验中显示出与吗啡相当的镇痛效果。许多化合物对大鼠脑膜中的[3H]纳洛酮结合位点显示出高亲和力。在最有效的衍生物中是化合物15和48。尽管是鸦片样的，但尝试用各种取代基修饰该活性未能产生拮抗作用。这些类似物中的一些在豚鼠5-羟色胺毒性试验中和在小鼠中由DL-5-羟色氨酸诱导的头抽搐模型中也显示出明显的持久性5-羟色胺拮抗作用。
• [EN] COMPOSITION COMPRISING A PESTICIDE AND AMIDE<br/>[FR] COMPOSITION COMPRENANT UN PESTICIDE ET UN AMIDE
  申请人：BASF SE

  公开号：WO2015067524A1

  公开（公告）日：2015-05-14

  The present invention relates to an aqueous composition comprising a pesticide and a certain carboxylicacid amide. The invention further relates to a method for controlling phytopathogenic fungi and/or undesirable plant growth and/or undesirable insect or mite infestation and/or for regulating the growth of plants, wherein the composition is allowed to act on the respective pests, the habitat thereof or the plants to be protected from the respective pest, on the soil and/or on undesirable plants and/or the crop plants and/or the habitat thereof. Furthermore, the invention relates to the use of the carboxylic acid amide as solvent for pesticides with no or low phytotoxicity. The present invention comprises combinations of preferred features with other preferred features.

  本发明涉及一种包含杀虫剂和某种羧酸酰胺的水性组合物。该发明还涉及一种控制植物病原真菌和/或不良植物生长和/或不良昆虫或螨虫侵袭和/或调节植物生长的方法，其中允许该组合物作用于相应的害虫、其栖息地或待保护的植物，土壤和/或不良植物和/或作物植物和/或其栖息地。此外，该发明涉及将羧酸酰胺用作对没有或低植物毒性的杀虫剂的溶剂。本发明包括首选特征与其他首选特征的组合。
• Composition for Removing Polymer
  申请人：Dongwoo Fine-Chem Co., Ltd.

  公开号：US20210300860A1

  公开（公告）日：2021-09-30

  Disclosed is a composition for removing polymers. The composition contains a fluorinated alkyl compound, a polar aprotic solvent, and an acyclic secondary or tertiary amine compound.

  揭示了一种用于去除聚合物的组合物。该组合物包含氟化烷基化合物、极性非质子溶剂和无环二级或三级胺化合物。
• [EN] PART-STREAM DISTILLATION<br/>[FR] DISTILLATION DE FLUX PARTIEL
  申请人：BASF SE

  公开号：WO2016066629A1

  公开（公告）日：2016-05-06

  A continuous process for the preparation of propylene oxide, comprising (a) reacting propene with hydrogen peroxide in a reaction apparatus in the presence of acetonitrile as solvent, obtaining a stream SO containing propylene oxide, acetonitrile, water, at least one further component B wherein the normal boiling point of the at least one component B is higher than the normal boiling point of acetonitrile; (b) separating propylene oxide from SO, obtaining a stream SI containing acetonitrile, water and the at least one further component B; (c) dividing S1 into two streams S2 and S3; (d) subjecting S3 to a vapor-liquid fractionation in a first fractionation unit, obtaining a vapor fraction stream S4 a being depleted, relative to S3, of at least one of the at least one component B and obtaining a liquid bottoms stream S4b, and subjecting at least part of the vapor fraction stream S4 a to a vapor-liquid fractionation in a second fractionation unit, obtaining a vapor fraction stream S4c and a liquid bottoms stream S4 being depleted, relative to S4a, of at least one of the at least one component B; (e) recycling at least a portion of S4, optionally after work-up, to (a).

  一种制备丙烯氧的连续工艺，包括(a)在存在乙腈作为溶剂的反应装置中，将丙烯与过氧化氢反应，得到含有丙烯氧、乙腈、水和至少一种进一步组分B的流SO；(b)从SO中分离丙烯氧，得到含有乙腈、水和至少一种进一步组分B的流SI；(c)将S1分成两个流S2和S3；(d)在第一分馏装置中对S3进行汽液分馏，得到贫化至少一种组分B的汽相流S4a相对于S3，并得到液体底流S4b，并对至少部分汽相流S4a进行第二分馏装置的汽液分馏，得到汽相流S4c和贫化至少一种组分B的液体底流S4；(e)将至少一部分S4回收，可选地经过后续处理后返回(a)。
• PROCESS FOR PREPARING PROPYLENE OXIDE
  申请人：BASF SE

  公开号：US20160176834A1

  公开（公告）日：2016-06-23

  A continuous process for the preparation of propylene oxide, comprising (i) providing a liquid feed stream comprising propene, hydrogen peroxide, acetonitrile, water, optionally propane, and at least one dissolved potassium salt of a phosphorus oxyacid wherein the molar ratio of potassium relative to phosphorus in the at least one potassium salt of a phosphorus oxyacid is in the range of from 0.6 to 1.4; (ii) passing the liquid feed stream provided in (i) into an epoxidation reactor comprising a catalyst comprising a titanium zeolite of structure type MVVW comprising zinc, and subjecting the liquid feed stream to epoxidation reaction conditions in the epoxidation reactor, obtaining a reaction mixture comprising propylene oxide, acetonitrile, water, the at least one dissolved potassium salt of a phosphorus oxyacid, optionally propene, and optionally propane; (iii) removing an effluent stream from the epoxidation reactor, the effluent stream comprising propylene oxide, acetonitrile, water, at least a portion of the at least one dissolved potassium salt of a phosphorus oxyacid, optionally propene, and optionally propane.

  一种制备丙烯醚的连续过程，包括(i)提供液态进料流，包括丙烯、过氧化氢、乙腈、水、可选的丙烷和至少一种磷氧酸钾盐，其中至少一种磷氧酸钾盐中钾与磷的摩尔比在0.6至1.4范围内；(ii)将提供的液态进料流引入包含一种结构类型为MVVW的钛沸石催化剂的环氧化反应器中，并在环氧化反应器中进行环氧化反应条件，得到反应混合物，包括丙烯醚、乙腈、水、至少一种磷氧酸钾盐、可选的丙烷和可选的丙烯；(iii)从环氧化反应器中移除流出的废液流，该废液流包括丙烯醚、乙腈、水、至少一部分磷氧酸钾盐、可选的丙烷和可选的丙烯。