4-(dimethylamino)-4-oxobutanoyl chloride

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-(dimethylamino)-4-oxobutanoyl chloride
• 英文别名: 4-(Dimethylamino)-4-oxobutanoyl chloride
• 化学式: C₆H₁₀ClNO₂
• 分子量: 163.604
• InChiKey: YRSTZSGOTZOKEI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-氟联苯 、 4-(dimethylamino)-4-oxobutanoyl chloride 在 三氯化铝 作用下， 生成 4-(2'-Fluoro-biphenyl-4-yl)-N,N-dimethyl-4-oxo-butyramide
  参考文献：
  名称：

  DE2141925

  摘要：

  公开号：

文献信息

• [EN] INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY<br/>[FR] INHIBITEURS DE LA VOIE WNT/BÊTA-CATÉNINE
  申请人：UNIV CALIFORNIA

  公开号：WO2019152536A1

  公开（公告）日：2019-08-08

  The present disclosure relates to compounds that are capable of modulating the WNT/Beta-Catenin pathway. The disclosure further relates to methods of treating colorectal cancer and other WNT/Beta-Catenin mediated cancers.

  本披露涉及能够调节WNT/Beta-Catenin通路的化合物。此外，该披露还涉及治疗结直肠癌和其他WNT/Beta-Catenin介导的癌症的方法。
• Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA
  作者：Cheng Wang、Lailiang Qu、Shang Li、Fucheng Yin、Limei Ji、Wan Peng、Heng Luo、Dehua Lu、Xingchen Liu、Xinye Chen、Lingyi Kong、Xiaobing Wang

  DOI：10.1021/acs.jmedchem.1c00567

  日期：2021.9.9
• EP3749640A1
  申请人：——

  公开号：EP3749640A1

  公开（公告）日：2020-12-16
• METHODS AND SYSTEMS FOR DELIVERING WOOD PRESERVATIVES
  申请人：Mizusawa Atsushi

  公开号：US20140017506A1

  公开（公告）日：2014-01-16

  The present application relates to wood preservation, for example, surfactants and phospholipids for improving wood preservation. Included are surfactants and phospholipids containing a 2-amino-N,N-dimethylacetamide. Provided are wood preservative compositions containing these surfactants or phospholipids, methods of applying such wood preservative compositions to wood, and wood products resultant from some such methods. Also provided are wood products containing the wood preservative compositions provided herein.
• INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY
  申请人：The Regents of the University of California

  公开号：US20210371384A1

  公开（公告）日：2021-12-02

  The present disclosure relates to compounds that are capable of modulating the WNT/Beta-Catenin pathway. The disclosure further relates to methods of treating colorectal cancer and other WNT/Beta-Catenin mediated cancers.