benzyl 6-deoxy-2,3,4-tri-O-acetyl-1-sulfonyl-α-L-rhamnopyranoside | 1048006-20-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: benzyl 6-deoxy-2,3,4-tri-O-acetyl-1-sulfonyl-α-L-rhamnopyranoside
• 英文别名: [(2S,3S,4R,5R,6S)-4,5-diacetyloxy-6-benzylsulfonyl-2-methyloxan-3-yl] acetate
• CAS: 1048006-20-7
• 化学式: C₁₉H₂₄O₉S
• 分子量: 428.46
• InChiKey: NINWDFABUNMAQZ-RNTHYAPCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  29
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  131
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  benzyl 6-deoxy-2,3,4-tri-O-acetyl-1-thio-α-L-rhamnopyranoside 在 HOF* CH₃CN 作用下， 以 氯仿 为溶剂， 反应 0.03h， 以95%的产率得到benzyl 6-deoxy-2,3,4-tri-O-acetyl-1-sulfonyl-α-L-rhamnopyranoside
  参考文献：
  名称：

  Application of HOF·CH3CN to the synthesis of glycosyl sulfones

  摘要：

  A fast, complete and clean conversion of thioglycosides into glycosyl sull'ones under mild acidic conditions is described, using the HOF center dot CH3CN complex at room temperature. This methodology affords glycosyl sull'ones in high yields and in excellent purity. (c) 2008 Elsevier Ltd. All rights reserved,

  DOI：

  10.1016/j.tet.2008.05.033

文献信息

• Application of HOF·CH3CN to the synthesis of glycosyl sulfones
  作者：Goreti Ribeiro Morais、Andrew J. Humphrey、Robert A. Falconer

  DOI：10.1016/j.tet.2008.05.033

  日期：2008.7

  A fast, complete and clean conversion of thioglycosides into glycosyl sull'ones under mild acidic conditions is described, using the HOF center dot CH3CN complex at room temperature. This methodology affords glycosyl sull'ones in high yields and in excellent purity. (c) 2008 Elsevier Ltd. All rights reserved,