N-(2,2-二甲氧基-1-羟基乙基)丙烯酰胺 | 112642-92-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-(2,2-二甲氧基-1-羟基乙基)丙烯酰胺
• 中文别名: N-(1-羟基-2,2-二甲氧基乙基)-2-丙烯酰胺
• 英文名称: N-(1-hydroxy-2,2-dimethoxyethyl)prop-2-enamide
• CAS: 112642-92-9
• 化学式: C₇H₁₃NO₄
• 分子量: 175.18
• InChiKey: XWQDTJROXGIDKW-UHFFFAOYSA-N

物化性质

• 沸点：
  96 °C
• 密度：
  1.1 g/mL at 25 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  67.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES
  申请人：Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

  公开号：US20150238597A1

  公开（公告）日：2015-08-27

  The present invention relates to the field of synthesizing and biologically evaluating of a novel class of carbohydrate-based vaccines. The new vaccines consist of a multi-modular structure which allows applying the vaccine to a whole variety of pathogenes. This method allows preparing vaccines against all pathogens expressing immunogenic carbohydrate antigens. As conjugation of antigenic carbohydrates to proteins is not required the conjugate vaccine is particularly heat stable. No refrigeration is required, a major drawback of protein-based vaccines.

  本发明涉及合成和生物评价一种新型基于碳水化合物的疫苗的领域。这种新疫苗由多模块结构组成，可以将疫苗应用于各种病原体。该方法允许制备针对所有表达免疫原碳水化合物抗原的病原体的疫苗。由于不需要将抗原碳水化合物与蛋白质结合，所以结合疫苗尤其耐热稳定。无需冷藏，这是基于蛋白质的疫苗的一个主要缺点。
• Polymer dispersion with a cross-linking resin, a method for producing the same and the use thereof
  申请人：——

  公开号：US20040044138A1

  公开（公告）日：2004-03-04

  The invention relates to a polymer dispersion which contains water, at least one polymer that has been produced by emulsion polymerisation, at least one protective colloid, at least one water-soluble acidic metallic salt and at least one cross-linking resin that is based on phenol-formaldehyde condensation products, hydroxymethyl-substituted imidazolidinones, such as 1,3-dimethylol-4,5-dihydroxy-imidazolidinone (4,5-dihydroxy-N,N′-dimethylolethylene urea), hydroxymethyl-substituted pyrimidinones, or hydroxymethyl-substituted triazinones or their auto-condensation products, or mixed condensates from two or more of the aforementioned compounds, or a mixture of two or more of the aforementioned compounds.

  本发明涉及一种聚合物分散体，其包含水、至少一种通过乳液聚合制备的聚合物、至少一种保护胶体、至少一种水溶性酸性金属盐和至少一种基于酚醛缩合产物、羟甲基取代咪唑啉酮（例如1,3-二甲基-4,5-二羟基咪唑啉酮（4,5-二羟基-N,N'-二甲基乙烯脲））、羟甲基取代嘧啶酮或羟甲基取代三嗪酮或其自缩合产物、或来自上述化合物中两种或更多的混合缩合物，或上述化合物中两种或更多的混合物。
• Cross-Linkable Monomers and Polymers and the Use Thereof
  申请人：Jakob Martin

  公开号：US20110190462A1

  公开（公告）日：2011-08-04

  The invention relates to novel cross-linkable monomers that may be polymerized with ethylenically unsaturated comonomers to form cross-linkable copolymers. Said copolymers may particularly be used in the form of aqueous dispersions as formaldehyde-free adhesives or as coatings with good water resistance. The cross-linkable monomer is a compound in acid or salt form comprising an anion of the formula (I) and one or more cations for producing electrical neutrality, where R 1 and R 2 represent, independently of one another, hydrogen alkyl, cycloalkyl, aryl, aralkyl, —COOR 5 , —COO − cat + or —CON(R 6 R 7 ), R 6 and R 7 represent, independently of one another, hydrogen, alkyl, or aryl, cat 4 represents a monovalent cation, and one of the groups R 1 or R 2 may also represent a group —X—R 4 —CR 5 (OH)SO 3 − ), wherein X, R 4 , and R 5 assume one of the meanings listed below, R 3 represents hydrogen, alkyl, or aryl, X is selected from the group of direct C—C bond, —O—, —CH 2 —O—, —CH 2 —NR 8 —, —COO— or —CONR 8 —, R 8 represents hydrogen, alkyl, or aryl, R 4 represents alkylene, polyoxyalkylene, cycloalkylene, or arylene, and R 5 represents hydrogen, alkyl, cycloalkyl, or aryl.

  本发明涉及新型交联单体，可以与乙烯基不饱和共聚单体聚合形成交联共聚物。所述共聚物可以作为无甲醛粘合剂的水性分散液或具有良好耐水性的涂料使用。所述交联单体是一种酸或盐形式的化合物，包括公式（I）的阴离子和一个或多个阳离子以产生电中性，其中R1和R2分别独立地表示氢，烷基，环烷基，芳基，芳基烷基，-COOR5，-COO-cat+或-CON（R6R7），R6和R7分别独立地表示氢，烷基或芳基，cat4表示一价阳离子，R1或R2中的一个也可以表示一个基团-X-R4-CR5（OH）SO3-，其中X，R4和R5分别取下面列出的含义之一，R3表示氢，烷基或芳基，X从直接C-C键，-O-，-CH2-O-，-CH2-NR8-，-COO-或-CONR8-的群中选择，R8表示氢，烷基或芳基，R4表示烷基，聚氧烷基，环烷基或芳基，R5表示氢，烷基，环烷基或芳基。
• Formaldehyde-free crosslinking emulsion polymer systems based on vinyl ester dialkoxyhydroxyethyl acrylamide co- and terpolymers
  申请人：National Starch and Chemical Investment Holding Corporation

  公开号：EP0514654A1

  公开（公告）日：1992-11-25

  Formaldehyde free crosslinking emulsion polymers are prepared by the addition of N-(2,2-dialkoxy-1-hydroxy)ethyl acrylamide to a vinyl ester based polymer. The resultant emulsions can be used as binders for nonwovens or fiberfill or as woodworking adhesives.

  无甲醛交联乳液聚合物是通过将 N-（2,2-二烷氧基-1-羟基）乙基丙烯酰胺添加到乙烯基酯聚合物中来制备的。制得的乳液可用作无纺布或纤维填充物的粘合剂或木工粘合剂。
• Self-crosslinking solvent borne pressure sensitive adhesives
  申请人：National Starch and Chemical Investment Holding Corporation

  公开号：EP0629639A1

  公开（公告）日：1994-12-21

  A pressure sensitive adhesive composition prepared from an organic solvent solution of an interpolymer, the interpolymer containing: i) at least about 80% by weight of at least one alkyl ester of acrylic or methacrylic acid containing 2 to 18 carbon atoms in the alkyl group; or a vinyl ester of an C₂-C₁₀ alkanoic acid or combination thereof; ii) 1 to 20% by weight of an ethylenically unsaturated monomer of the general formula: where R₁ is H or CH₃ with the proviso that (a) when X is NH and R₂ is H, R₃ is or O-R₅ ; (b) when X is NH and R₂ is OH; R₃ is and (c) when X is O, R₂ is H and R₃ is where in (a), (b) and (c), R₄ is C₁-C₄ alkyl or (CH₂)n and n is 2-4 and R₅ is H or C₁-C₄ alkyl; and iii) 0 to 10% by weight of a hydroxyl containing monomer.

  一种由互聚物的有机溶剂溶液制备而成的压敏型粘合剂组合物，该互聚物含有 i) 至少约 80%（按重量计）的丙烯酸或甲基丙烯酸的烷基酯，烷基中含有 2 至 18 个碳原子；或 C₂-C₁₀烷酸的乙烯基酯或其组合； ii) 1%至 20%（按重量计）的通式乙烯基不饱和单体： 其中 R₁ 是 H 或 CH₃，但 (a) 当 X 是 NH 和 R₂ 是 H 时，R₃ 是 或 O-R₅ ； (b) 当 X 是 NH 且 R₂ 是 OH 时，R₃ 是 和 (c) 当 X 为 O，R₂ 为 H，R₃ 为 其中在(a)、(b)和(c)中，R₄是 C₁-C₄烷基或 (CH₂)n 且 n 是 2-4，R₅是 H 或 C₁-C₄ 烷基；以及 iii) 0 至 10%（重量百分比）的含羟基单体。