N-hexyl-3,3-dimethylbutanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-hexyl-3,3-dimethylbutanamide
• 化学式: C₁₂H₂₅NO
• mdl: MFCD02860363
• 分子量: 199.33
• InChiKey: PTZYAZQQJIPOFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.916
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Substituted 4-azaindoles and their use as GluN2B receptor modulators
  申请人：Janssen Pharmaceutica NV

  公开号：US10377753B2

  公开（公告）日：2019-08-13

  Substituted 4-azaindoles as NR2B receptor ligands. Such compounds may be used in NR2B receptor modulation and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by NR2B receptor activity.

  取代的 4-氮杂吲哚作为 NR2B 受体配体。此类化合物可用于 NR2B 受体调节以及治疗由 NR2B 受体活性介导的疾病状态、紊乱和病症的药物组合物和方法中。
• SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS
  申请人：Janssen Pharmacueitica NV

  公开号：US20180208595A1

  公开（公告）日：2018-07-26

  Substituted 4-azaindoles as NR2B receptor ligands. Such compounds may be used in NR2B receptor modulation and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by NR2B receptor activity.