2,2-dimethyl-N-(2-morpholin-4-ylethyl)butanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,2-dimethyl-N-(2-morpholin-4-ylethyl)butanamide
• 化学式: C₁₂H₂₄N₂O₂
• 分子量: 228.33
• InChiKey: KMOTYIAAVTVTNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  41.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Inhibitors of VEGF receptor and HGF receptor signaling
  申请人：Saavedra Mario Oscar

  公开号：US20070004675A1

  公开（公告）日：2007-01-04

  The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions

  该发明涉及抑制VEGF受体信号和HGF受体信号。该发明提供了抑制VEGF受体信号和HGF受体信号的化合物和方法。该发明还提供了治疗细胞增殖性疾病和病况的组合物和方法。
• Compounds for increasing lipid synthesis and storage
  申请人：NUtech Ventures

  公开号：US10351883B2

  公开（公告）日：2019-07-16

  This invention relates to methods for increasing lipid accumulation and lipid production in cells. Methods of producing biofuel from cells and preparing nutraceuticals comprising lipids produced according to a method provided herein are also provided.

  本发明涉及增加细胞中脂质积累和脂质生产的方法。本发明还提供了从细胞中生产生物燃料的方法，以及制备包含根据本发明提供的方法生产的脂质的营养保健品的方法。
• Nitrogenous heterocyclic aromatic compound, preparation method therefor, pharmaceutical composition thereof, and application thereof
  申请人：SHANGHAI YINGLI PHARMACEUTICAL CO., LTD

  公开号：US11466003B2

  公开（公告）日：2022-10-11

  Provided are a nitrogenous heterocyclic aromatic compound, a preparation method therefor, a pharmaceutical composition thereof, and an application thereof. The nitrogenous heterocyclic aromatic compound can be used for treating and/or preventing various diseases mediated by ALK5.

  本文提供了一种含氮杂环芳香化合物、其制备方法、药物组合物及其应用。该含氮杂环芳香化合物可用于治疗和/或预防由 ALK5 介导的各种疾病。
• Compounds for Increasing Lipid Synthesis and Storage
  申请人：NUtech Ventures

  公开号：US20200071735A1

  公开（公告）日：2020-03-05

  This invention relates to methods for increasing lipid accumulation and lipid production in cells. Methods of producing biofuel from cells and preparing nutraceuticals comprising lipids produced according to a method provided herein are also provided.
• NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF
  申请人：SHANGHAI YINGLI PHARMACEUTICAL CO., LTD

  公开号：US20210300916A1

  公开（公告）日：2021-09-30

  Provided are a nitrogenous heterocyclic aromatic compound, a preparation method therefor, a pharmaceutical composition thereof, and an application thereof. The nitrogenous heterocyclic aromatic compound can be used for treating and/or preventing various diseases mediated by ALK5.