2-methyl-N-(2-methylpropyl)butanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-methyl-N-(2-methylpropyl)butanamide
• 化学式: C₉H₁₉NO
• 分子量: 157.25
• InChiKey: SFUDZDQTSNURQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• MATERIAL FOR BLOOD PURIFICATION
  申请人：Toray Industries, Inc.

  公开号：EP3513821A1

  公开（公告）日：2019-07-24

  An object of the present invention is to provide a material for blood purification having the capability to remove cytokines and activated leukocyte-activated platelet complexes. The present invention provides a material for blood purification, the material containing a water-insoluble material in which a ligand having an amide group(s) and an amino group(s) is bound to a substrate, wherein the content of the amide group(s) is 3.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material; and wherein the content of the amino group(s) is 1.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material.

  本发明的目的是提供一种血液净化材料，该材料具有去除细胞因子和活化白细胞-活化血小板复合物的能力。本发明提供了一种血液净化材料，该材料含有一种水不溶性材料，其中具有酰胺基团和氨基的配体与基质结合，其中酰胺基团的含量为每 1 克水不溶性材料干重 3.0 至 7.0 毫摩尔；氨基的含量为每 1 克水不溶性材料干重 1.0 至 7.0 毫摩尔。
• Pyrimidine compounds and methods using the same
  申请人：Yuma Therapeutics, Inc.

  公开号：US10961254B2

  公开（公告）日：2021-03-30

  The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.

  本发明涉及作为热休克蛋白 90 家族伴侣蛋白抑制剂的 2-氨基-4-芳基嘧啶和 2-氨基-4-芳基三嗪化合物。本发明还包括本发明化合物和组合物的药物组合物和试剂盒。本发明进一步涉及这些化合物和组合物用于治疗受试者疾病的医疗用途。例如，该疾病是一种神经退行性疾病。
• SUSTAINED RELEASE HYDROGEL-BASED STIMULANT
  申请人：University of New Hampshire

  公开号：US20150133565A1

  公开（公告）日：2015-05-14

  The present invention relates to a thermo-responsive hydrogel polymer formulated with one or more active agents selected from the group consisting of menthol and menthone, wherein said active agents are effective in invigorating the user and/or effective in relieving fatigue.
• US5224987A
  申请人：——

  公开号：US5224987A

  公开（公告）日：1993-07-06