(Z)-octadec-6-en-1-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-octadec-6-en-1-ol
• 英文别名: octadec-6-en-1-ol
• 化学式: C₁₈H₃₆O
• 分子量: 268.5
• InChiKey: TVPWKOCQOFBNML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  19
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• External preparation
  申请人：Sansho Seiyaku Co., Ltd.

  公开号：EP0355842A2

  公开（公告）日：1990-02-28

  This invention provides an external preparation effectively preventing skin pigmentation caused by melanin production, i.e. spots or freckle, and having also superior actions on fair-skin making up, the external preparation containing unsaturated straight-­chain fatty acids or unsaturated straight-chain aliphatic alcohols or the derivatives thereof as effective ingredients.

  本发明提供了一种外用制剂，可有效防止因黑色素生成而引起的皮肤色素沉着，即色斑或雀斑，同时对白皙皮肤的妆容也有卓越功效，该外用制剂含有不饱和直链脂肪酸或不饱和直链脂肪醇或其衍生物作为有效成分。
• Crystallizable polylactone copolymers prepared from mono- and di-functional polymerization initiators
  申请人：ETHICON, INC.

  公开号：EP1374921A1

  公开（公告）日：2004-01-02

  The present invention is directed to absorbable polylactone copolymers prepared in part from about 2 to about 80 mole percent glycolide, utilizing a combination of a monofunctional polymerization initiator and a di-functional polymerization initiator, to achieve rates of crystallization of the copolymer of at least about 2 times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the mono-functional or the di-functional polymerization initiator alone. Medical devices containing such copolymers are also disclosed.

  本发明的目的是利用单官能团聚合引发剂和双官能团聚合引发剂的组合，制备部分由约 2 至约 80 摩尔百分数的羟基乙内酯组成的可吸收的聚乳酸共聚物，使共聚物的结晶速率比单独使用单官能团或双官能团聚合引发剂的类似工艺制作的共聚物的结晶速率至少快约 2 倍。此外，还公开了含有这种共聚物的医疗器械。
• Polymerization process using mono-and di-functional initiators to prepare fast crystallizing polylactone copolymers.
  申请人：ETHICON, INC.

  公开号：EP1375557B1

  公开（公告）日：2006-08-02
• POLOXAMER FOAMABLE PHARMACEUTICAL COMPOSITIONS WITH ACTIVE AGENTS AND/OR THERAPEUTIC CELLS AND USES
  申请人：Foamix Ltd.

  公开号：EP2242476A2

  公开（公告）日：2010-10-27
• Polymerization process using mono-and di-functional initiators to prepare fast crystallizing polylactone copolymers
  申请人：ETHICON, INC.

  公开号：US20040006199A1

  公开（公告）日：2004-01-08

  The present invention is directed to a process for making an absorbable polylactone copolymer prepared in part from about 2 to about 80 mole percent glycolide, which process utilizes a combination of a monofunctional polymerization initiator and a di-functional polymerization initiator, to achieve rates of crystallization of the copolymer of at least about 2 times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the mono-functional or the di-functional polymerization initiator alone. Absorbable polylactone copolymers prepared by such processes and medical devices containing such copolymers are also disclosed.