N-(3-methoxypropyl)ethanesulfonamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N-(3-methoxypropyl)ethanesulfonamide
• 化学式: C₆H₁₅NO₃S
• mdl: MFCD03390543
• 分子量: 181.26
• InChiKey: QDTOKTDABUELHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  63.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Salts of heterocyclic modulators of HIF activity for treatment of disease
  申请人：Board of Regents, The University of Texas System

  公开号：US10888554B2

  公开（公告）日：2021-01-12

  The present disclosure relates to salts of heterocyclic compounds and methods that inhibit HIF pathway activity. The compounds are designed to treat or prevent cancer and other hypoxia-mediated diseases.

  本公开涉及抑制 HIF 通路活性的杂环化合物盐和方法。 这些化合物旨在治疗或预防癌症和其他缺氧介导的疾病。
• Arylacetate Derivatives Having Isoxazole Skeleton
  申请人：Kanda Yasuhiko

  公开号：US20090062531A1

  公开（公告）日：2009-03-05

  A compound of the formula (I): pharmaceutically acceptable salt or solvate thereof, wherein Y is a group of the formula: wherein Ring A is optionally substituted aryl or optionally substituted heteroaryl, X 3 is COOR 17 or the like Y is not optionally substituted phenyl which is substituted with the formula: —CR 9 R 10 X 3 at the para position, R 1 to R 10 are each independently halogen, hydroxy, optionally substituted lower alkyl, optionally substituted aryl or the like, X 1 is —O—, —S— or the like.
• SALTS OF HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE
  申请人：Board of Regents, The University of Texas System

  公开号：US20200171017A1

  公开（公告）日：2020-06-04

  The present disclosure relates to salts of heterocyclic compounds and methods that inhibit HIF pathway activity. The compounds are designed to treat or prevent cancer and other hypoxia-mediated diseases.
• US7781469B2
  申请人：——

  公开号：US7781469B2

  公开（公告）日：2010-08-24