2-isopropoxy-octan-1-ol | 22460-56-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-isopropoxy-octan-1-ol
• 英文别名: 2-Propan-2-yloxyoctan-1-ol；2-propan-2-yloxyoctan-1-ol
• CAS: 22460-56-6
• 化学式: C₁₁H₂₄O₂
• 分子量: 188.31
• InChiKey: PUMVFXVAFBIGJA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  异丙醇 、 1,2-环氧辛烷 在 CuO on silica 作用下， 反应 18.0h， 生成 2-isopropoxy-octan-1-ol
  参考文献：
  名称：

  CuO / SiO 2：一种简单而有效的固体酸催化剂 为了 环氧化物 开环

  摘要：

  一种廉价，无毒，易于制备且易于使用的负载型CuO材料已被证明是一种非常有效的材料 催化剂 对于...的酒精中毒 环氧化物以非常高的收率得到β-烷氧基醇，而不会产生任何浪费。这催化剂 本质上是异质的，无需任何重新活化处理即可重复使用。

  DOI：

  10.1039/c0gc00719f

文献信息

• An Environmentally Benign Catalytic Method for Efficient and Selective Nucleophilic Ring Opening of Oxiranes by Zirconium Tetrakis(dodecyl Sulfate)
  作者：Maasoumeh Jafarpour、Abdolreza Rezaeifard、Marzieh Aliabadi

  DOI：10.1002/hlca.200900239

  日期：2010.3

  An operationally simple and environmentally benign protocol for a highly regio‐ and chemoselective preparation of β‐substituted alcohols by means of ring‐opening reactions of oxiranes with various aliphatic alcohols, H2O, NaN3, and NaCN as nucleophiles in the presence of catalytic amounts of zirconium tetrakis(dodecyl sulfate) as Lewis acid/surfactant‐combined catalysts (LASCs) was developed. The high

  一种操作简单且对环境无害的方案，可在催化作用下，通过环氧乙烷与各种脂肪族醇，H 2 O，NaN 3和NaCN作为亲核体的开环反应，高度区域和化学选择性地制备β-取代的醇研制了一定数量的四（十二烷基硫酸）锆作为路易斯酸/表面活性剂组合催化剂（LASC）。催化剂的高效率通过在所需时间内获得的高产物收率，尤其是通过Zr IV配合物的可重复使用性得到了证实。
• MOFs and their grafted analogues: regioselective epoxide ring-opening with Zr₆ nodes
  作者：Nicholas E. Thornburg、Yangyang Liu、Peng Li、Joseph T. Hupp、Omar K. Farha、Justin M. Notestein

  DOI：10.1039/c6cy01093h

  日期：——

  Zirconium(iv)-containing metal–organic framework (MOF) catalysts NU-1000 and MOF-808 were compared to analogous catalysts synthesized by grafting the nodes onto bare and functionalized silica.

  比较了含锆（IV）的金属有机骨架（MOF）催化剂NU-1000和MOF-808与将节点嫁接到裸硅和功能化硅上合成的类似催化剂。
• Eschinasi,E.H., Israel Journal of Chemistry, 1968, vol. 6, p. 713 - 721
  作者：Eschinasi,E.H.

  DOI：——

  日期：——
• Process for the separation of optical isomers of the corey lactone
  申请人：Chinoin Gyógyszer és Vegyészeti Termékek Gyára Zrt.

  公开号：EP1968916B1

  公开（公告）日：2012-07-11
• [EN] COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION<br/>[FR] COMPOSITION D'AGENT DE SENSATION DE FRAÎCHEUR ET COMPOSITION D'AGENT DE STIMULATION SENSORIELLE
  申请人：TAKASAGO PERFUMERY CO LTD

  公开号：WO2009123355A2

  公开（公告）日：2009-10-08

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from l-menthol, l-isopulegol, 3-(l-menthoxy)propan-1,2-diol, 2-(l-menthoxy)ethan-1-ol, 3-(l-menthoxy)propan-1-ol, 2-methyl-3-(l-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.