N1-(4-Heptafluoroisopropyl-2-methylphenyl)-N2-(1-methyl-2-methylthioethyl)-3-methylsulfonylphthalamide | 272452-42-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N1-(4-Heptafluoroisopropyl-2-methylphenyl)-N2-(1-methyl-2-methylthioethyl)-3-methylsulfonylphthalamide
• 英文别名: 1-N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-2-N-(1-methylsulfanylpropan-2-yl)-3-methylsulfonylbenzene-1,2-dicarboxamide
• CAS: 272452-42-3
• 化学式: C₂₃H₂₃F₇N₂O₄S₂
• 分子量: 588.567
• InChiKey: PSUMDLCDXYNMPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  38
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  126
• 氢给体数：
  2
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  N-(4-Heptafluoroisopropyl-2-methylphenyl)-3-methylsulfonylphthalimide 、 1-(甲基硫烷基)丙-2-胺 在 溶剂黄146 作用下， 以 1,4-二氧六环 为溶剂， 反应 3.0h， 以55%的产率得到N1-(4-Heptafluoroisopropyl-2-methylphenyl)-N2-(1-methyl-2-methylthioethyl)-3-methylsulfonylphthalamide
  参考文献：
  名称：

  Process for production of thioalkylamine derivatives

  摘要：

  本发明涉及一种由通式（I）表示的硫代烷胺衍生物；以及其生产工艺：其中R1和R2中的每一个是H，（C1-C4）烷基，（C3-C8）环烷基，（C3-C8）环烷基（C1-C4）烷基，（取代）苯基，（取代）苯基（C1-C4）烷基，或类似物；R3和R4中的每一个是H或（C1-C4）烷基；R5和R6中的每一个是H，（C1-C4）烷基，（取代）苯基或（取代）苯基（C1-C4）烷基；或者R1和R2，R1和R3或R5，R3和R4，R3和R5或R5和R6中的每一个组合形成较低的烷基；R为（C1-C12）烷基，（C3-C8）环烷基，（C3-C8）环烷基（C1-C4）烷基，（取代）苯基，（取代）苯基（C1-C4）烷基，萘基，（取代）芳香杂环基，或类似物。

  公开号：

  US06639109B1

文献信息

• Phthalamide derivatives, or salt thereof agrohorticultural insecticide, and method for using the same
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP1006107A2

  公开（公告）日：2000-06-07

  The present invention provides a phthalamide derivative of the formula (I): [wherein A1 is (substituted) C1-C8 alkylene, (substituted) C3-C8 alkenylene, (substituted) C3-C8 alkynylene, etc., R1 is H, (halo) C3-C6 cycloalkyl, (substituted) phenyl, (substituted) heterocycle, -A2-R4, etc., R2 and R3 are H, C3-C6 cycloalkyl, -A2-R4, etc., A2 is -C(=O)-, -C(=S)- or -C(=NR5)-, R4 is H, alkyl, (substituted) phenyl, (substituted) heterocycle, etc., X and Y are halogen, cyano, nitro, (halo) C1-C6 alkyl, (halo) C1-C6 alkoxy, etc., 1 is 0-4, m is 0-5, n is 0-2]; and an agrohorticultural insecticide containing said compound as active ingredient and exhibiting an excellent insecticidal effect.

  本发明提供了一种式（I）的邻苯二甲酰胺衍生物： [其中 A1 是（取代）C1-C8 亚烷基、（取代）C3-C8 烯基、（取代）C3-C8 亚炔基等，R1 是 H、（卤代）C3-C6 环烷基、（取代）苯基、（取代）杂环、-A2-R4 等，R2 和 R3 是 H、C3-C6 环烷基、-A2-R4 等、A2是-C(＝O)-、-C(＝S)-或-C(＝NR5)-，R4是H、烷基、（取代的）苯基、（取代的）杂环等，X和Y是卤素、氰基、硝基、（卤代）C1-C6烷基、（卤代）C1-C6烷氧基等，1是0-4，m是0-5，n是0-2]；以及一种含有上述化合物作为活性成分并具有优异杀虫效果的农用园艺杀虫剂。
• THIOALKYLAMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：EP1216988A1

  公开（公告）日：2002-06-26

  The present invention relates to a thioalkylamine derivative represented by general formula (I); and a process for production thereof: wherein each of R1 and R2 is H, (C1-C4)alkyl, (C3-C8)cycloalkyl, (C3-C8)cycloalkyl (C1-C4) alkyl, (substituted) phenyl, (substituted) phenyl(C1-C4) alkyl, or the like; each of R3 and R4 is H or a (C1-C4)alkyl group; each of R5 and R6 is H, (C1-C4)alkyl, a (substituted) phenyl group or a (substituted) phenyl(C1-C4)alkyl group; alternatively each of R1 and R2, R1 and R3 or R5, R3 and R4, R3 and R5, or R5 and R6 may together form lower alkylene; and R is (C1-C12)alkyl, (C3-C8)cycloalkyl, (C3-C8)cycloalkyl (C1-C4) alkyl, (substituted) phenyl, (substituted) phenyl (C1-C4)alkyl, a naphthyl group, a (substituted) aromatic heterocyclic, or the like.

  本发明涉及通式（I）所代表的硫代烷基胺衍生物及其生产工艺： 其中R1和R2各自为H、(C1-C4)烷基、(C3-C8)环烷基、(C3-C8)环烷基(C1-C4)烷基、(取代)苯基、(取代)苯基(C1-C4)烷基或类似物；R3和R4各自为H或(C1-C4)烷基；R5和R6各自为H、(C1-C4)烷基、(取代)苯基或(取代)苯基(C1-C4)烷基；或者，R1 和 R2、R1 和 R3 或 R5、R3 和 R4、R3 和 R5 或 R5 和 R6 可共同形成低级亚烷基；R 是 (C1-C12)烷基、(C3-C8)环烷基、(C3-C8)环烷基 (C1-C4) 烷基、（取代的）苯基、（取代的）苯基 (C1-C4)烷基、萘基、（取代的）芳香杂环基或类似基团。
• US6603044B1
  申请人：——

  公开号：US6603044B1

  公开（公告）日：2003-08-05
• US6639109B1
  申请人：——

  公开号：US6639109B1

  公开（公告）日：2003-10-28
• Process for production of thioalkylamine derivatives
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：US06639109B1

  公开（公告）日：2003-10-28

  The present invention relates to a thioalkylamine derivative represented by general formula (I); and a process for production thereof: wherein each of R1 and R2 is H, (C1-C4)alkyl, (C3-C8)cycloalkyl, (C3-C8)cycloalkyl(C1-C4)alkyl, (substituted) phenyl, (substituted) phenyl(C1-C4)alkyl, or the like; each of R3 and R4 is H or a (C1-C4)alkyl group; each of R5 and R6 is H, (C1-C4)alkyl, a (substituted) phenyl group or a (substituted) phenyl(C1-C4)alkyl group; alternatively each of R1 and R2, R1 and R3 or R5, R3 and R4, R3 and R5 or R5 and R6 may together form lower alkylene; and R is (C1-C12)alkyl, (C3-C8)cycloalkyl, (C3-C8)cycloalkyl(C1-C4)alkyl, (substituted) phenyl, (substituted) phenyl(C1-C4)alkyl, a naphthyl group, a (substituted) aromatic heterocyclic, or the like.

  本发明涉及一种由通式（I）表示的硫代烷胺衍生物；以及其生产工艺：其中R1和R2中的每一个是H，（C1-C4）烷基，（C3-C8）环烷基，（C3-C8）环烷基（C1-C4）烷基，（取代）苯基，（取代）苯基（C1-C4）烷基，或类似物；R3和R4中的每一个是H或（C1-C4）烷基；R5和R6中的每一个是H，（C1-C4）烷基，（取代）苯基或（取代）苯基（C1-C4）烷基；或者R1和R2，R1和R3或R5，R3和R4，R3和R5或R5和R6中的每一个组合形成较低的烷基；R为（C1-C12）烷基，（C3-C8）环烷基，（C3-C8）环烷基（C1-C4）烷基，（取代）苯基，（取代）苯基（C1-C4）烷基，萘基，（取代）芳香杂环基，或类似物。