4-butylsulfanyl-aniline; hydrochloride | 92286-68-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 4-butylsulfanyl-aniline; hydrochloride
• 英文别名: 4-Butylmercapto-anilin; Hydrochlorid；[4-(Butylthio)phenyl]amine hydrochloride；4-butylsulfanylaniline;hydrochloride
• CAS: 92286-68-5
• 化学式: C₁₀H₁₅NS*ClH
• 分子量: 217.763
• InChiKey: OINAQVGMRKKPGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.58
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  51.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  氰胺 、 4-butylsulfanyl-aniline; hydrochloride 反应 0.25h， 生成 N-(4-Butylsulfanyl-phenyl)-guanidine
  参考文献：
  名称：

  Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts

  摘要：

  A series of 4-substituted phenylguanidinium derivatives was synthesized and its antimicrobial activity was evaluated in vitro against eight potentially pathogenic strains of fungi.

  DOI：

  10.1016/j.farmac.2004.03.001
• 作为产物：
  描述：

  对硝基苯基正丁基硫醚 在 盐酸 、 tin(ll) chloride 作用下， 以 乙醚 为溶剂， 反应 2.0h， 以43%的产率得到4-butylsulfanyl-aniline; hydrochloride
  参考文献：
  名称：

  Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts

  摘要：

  A series of 4-substituted phenylguanidinium derivatives was synthesized and its antimicrobial activity was evaluated in vitro against eight potentially pathogenic strains of fungi.

  DOI：

  10.1016/j.farmac.2004.03.001

文献信息

• Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts
  作者：Gabriela Braunerová、Vladimír Buchta、Luis Silva、Jiří Kuneš、Karel Palát

  DOI：10.1016/j.farmac.2004.03.001

  日期：2004.6

  A series of 4-substituted phenylguanidinium derivatives was synthesized and its antimicrobial activity was evaluated in vitro against eight potentially pathogenic strains of fungi.