The present invention relates to benzoxazole derivatives represented by the Formula 1, which has an inhibitory activity against interleukin-6 (IL-6), a method for preparation thereof, and a pharmaceutical composition containing the same. The compound represented by the Formula 1 according to the present invention has a superior inhibitory activity against interleukin-6, and therefore, can be practically applied for prevention and treatment of diseases caused by abnormal interleukin-6 activity.
本发明涉及由公式1表示的苯并
噁唑衍
生物,其具有对白细胞介素-6(IL-6)的抑制活性,以及其制备方法和含有该化合物的药物组合物。根据本发明的公式1所表示的化合物具有优越的抑制白细胞介素-6的活性,因此,可以实际应用于预防和治疗由异常白细胞介素-6活性引起的疾病。