4-[4-({1-[(trimethylsilyl)methyl]ethenyl}phenyl)dimethylsilyl]benzaldehyde | 445399-06-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[4-({1-[(trimethylsilyl)methyl]ethenyl}phenyl)dimethylsilyl]benzaldehyde
• 英文别名: 4-[Dimethyl-[4-(3-trimethylsilylprop-1-en-2-yl)phenyl]silyl]benzaldehyde
• CAS: 445399-06-4
• 化学式: C₂₁H₂₈OSi₂
• 分子量: 352.624
• InChiKey: WRJUWEOGFJKKPU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.67
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  硅烷,[2-(4-溴苯基)-2-丙烯基]三甲基- 在 正丁基锂 、 4-甲基苯磺酸吡啶 作用下， 以 四氢呋喃 为溶剂， 生成 4-[4-({1-[(trimethylsilyl)methyl]ethenyl}phenyl)dimethylsilyl]benzaldehyde
  参考文献：
  名称：

  Asymmetric Synthesis of Chiral Polymers by Means of Repetitive Addition of Allylsilane to Aldehyde

  摘要：

  制备了同时具有烯丙基三甲基硅氧基和甲酰基的单体。采用手性（酰氧基）硼烷启动单体的重复聚加反应，得到具有主链构型手性的光学活性聚合物。通过对降解产物的分析评估了手性聚合物的光学纯度。

  DOI：

  10.1055/s-2002-28502

文献信息

• Asymmetric Synthesis of Chiral Polymers by Means of Repetitive Addition of Allylsilane to Aldehyde
  作者：Shinichi Itsuno、Toshihiro Kumagai

  DOI：10.1055/s-2002-28502

  日期：——

  Monomers having both allyltrimethylsilyl and formyl groups were prepared. Chiral (acyloxy)borane initiated the repetitive polyaddition of the monomers to give optically active polymers having main chain configurational chirality. Optical purity of the chiral polymer was evaluated by the analysis of the degradation product.

  制备了同时具有烯丙基三甲基硅氧基和甲酰基的单体。采用手性（酰氧基）硼烷启动单体的重复聚加反应，得到具有主链构型手性的光学活性聚合物。通过对降解产物的分析评估了手性聚合物的光学纯度。
• Asymmetric Polymer Synthesis by Repetitive SakuraiHosomi Allylation Reaction of Compounds Possessing Both Formyl and Allylsilane Functions
  作者：Shinichi Itsuno、Toshihiro Kumagai

  DOI：10.1002/1522-2675(200210)85:10<3185::aid-hlca3185>3.0.co;2-b

  日期：2002.10

  Trialkylallylsilanes generally react with aldehydes in the presence of a Lewis acid to the corresponding homoallylic alcohols. Chiral Lewis acids promote the same reaction to yield the enantiomerically-enriched homoallylalcohols. We have prepared four compounds (7-10) that possess both formyl and allylsilane functions. Lewis acids initiated self-polyaddition reactions of these compounds by means of repetitive allylation. The use of chiral Lewis acids resulted in the formation of optically active polymers that possess exo-methylene and secondary OH functions in their main chain. The optical purity of these chiral polymers was estimated based on the results of model asymmetric reactions between benzaldehyde and beta-substituted allylsilanes and by controlled degradation.