1-(4'-methylphenyl)-3-(4"-ethylphenyl)-4-trifluoromethylbenzene | 1419798-87-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4'-methylphenyl)-3-(4"-ethylphenyl)-4-trifluoromethylbenzene
• 英文别名: 2-(4-Ethylphenyl)-4-(4-methylphenyl)-1-(trifluoromethyl)benzene；2-(4-ethylphenyl)-4-(4-methylphenyl)-1-(trifluoromethyl)benzene
• CAS: 1419798-87-0
• 化学式: C₂₂H₁₉F₃
• 分子量: 340.388
• InChiKey: DOJBAIYBCUXNLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,4-二氯三氟甲苯 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 14.0h， 生成 1-(4'-methylphenyl)-3-(4"-ethylphenyl)-4-trifluoromethylbenzene
  参考文献：
  名称：

  Synthesis of trifluoromethyl-substituted bi- and terphenyls by site-selective Suzuki–Miyaura reactions of various dihalogenated trifluoromethyl-benzene derivatives

  摘要：

  A variety of trifluoromethylated bi- and terphenyls were prepared by site-selective Suzuki-Miyaura cross-coupling reactions of various dihalogenated trifluoromethyl-substituted benzene derivatives. The reactions proceed with excellent site-selectivities. (c) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2012.11.005

文献信息

• Synthesis of trifluoromethyl-substituted bi- and terphenyls by site-selective Suzuki–Miyaura reactions of various dihalogenated trifluoromethyl-benzene derivatives
  作者：Iftikhar Ali、Baraa Siyo、Zahid Hassan、Imran Malik、Ihsan Ullah、Asad Ali、Muhammad Nawaz、Jamshed Iqbal、Tamás Patonay、Alexander Villinger、Peter Langer

  DOI：10.1016/j.jfluchem.2012.11.005

  日期：2013.1

  A variety of trifluoromethylated bi- and terphenyls were prepared by site-selective Suzuki-Miyaura cross-coupling reactions of various dihalogenated trifluoromethyl-substituted benzene derivatives. The reactions proceed with excellent site-selectivities. (c) 2012 Elsevier B.V. All rights reserved.