O-isopropyl-Se-2-bromobenzyl phenylphosphonodiselenoate | 1388829-77-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: O-isopropyl-Se-2-bromobenzyl phenylphosphonodiselenoate
• 英文别名: (2-Bromophenyl)methylselanyl-phenyl-propan-2-yloxy-selanylidene-lambda5-phosphane；(2-bromophenyl)methylselanyl-phenyl-propan-2-yloxy-selanylidene-λ5-phosphane
• CAS: 1388829-77-3
• 化学式: C₁₆H₁₈BrOPSe₂
• 分子量: 495.116
• InChiKey: DZRRXFPKGIFEBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.33
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  异丙醇 、 Woollins 试剂 、 2-溴溴苄 在 sodium 作用下， 以 四氢呋喃 为溶剂， 反应 20.0h， 以0.415 g的产率得到O-isopropyl-Se-2-bromobenzyl phenylphosphonodiselenoate
  参考文献：
  名称：

  Sodium phenyldiselenophosphonate salts and Se-alkyl-O-alkylphenyl-phosphonodiselenoates and Se,Se′-dialkyl-O,O′-dialkyl-bis(phenylphosphonodiselenoate)s

  摘要：

  The reaction of sodium alkoxides [(RONa)-O-1, R-1 = CH3, CH3CH2, (CH3)(2)CH and CH3CH2CH2] with 2,4-diphenyl-1,3-diselenadiphosphetane-2,4-diselenide [PhP(Se)(mu-Se)](2) (Woollins' reagent, WR) gave the non-symmetric sodium phenyldiselenophosphonate salts 1a-1d, the latter were further treated with haloalkanes [(RX)-X-2, R-2 = alkyl and aryl; X = Br, Cl and I] or dihaloalkanes [Br-(CH2)(n)-Br, n = 1-3 and BrCH2C6H4CH2Br-p] to afford a series of new Se-alkyl O-alkylphenylphosphonodiselenoate esters 2a-2k and Se,Se'-dialkyl-O,O'-dialkyl bis(phenylphosphonodiselenoate) esters 3a-3j in good to excellent yields. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.05.010

文献信息

• Sodium phenyldiselenophosphonate salts and Se-alkyl-O-alkylphenyl-phosphonodiselenoates and Se,Se′-dialkyl-O,O′-dialkyl-bis(phenylphosphonodiselenoate)s
  作者：Guoxiong Hua、J. Derek Woollins

  DOI：10.1016/j.poly.2012.05.010

  日期：2012.7

  The reaction of sodium alkoxides [(RONa)-O-1, R-1 = CH3, CH3CH2, (CH3)(2)CH and CH3CH2CH2] with 2,4-diphenyl-1,3-diselenadiphosphetane-2,4-diselenide [PhP(Se)(mu-Se)](2) (Woollins' reagent, WR) gave the non-symmetric sodium phenyldiselenophosphonate salts 1a-1d, the latter were further treated with haloalkanes [(RX)-X-2, R-2 = alkyl and aryl; X = Br, Cl and I] or dihaloalkanes [Br-(CH2)(n)-Br, n = 1-3 and BrCH2C6H4CH2Br-p] to afford a series of new Se-alkyl O-alkylphenylphosphonodiselenoate esters 2a-2k and Se,Se'-dialkyl-O,O'-dialkyl bis(phenylphosphonodiselenoate) esters 3a-3j in good to excellent yields. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.