N-benzenesulfonyl-4,5-dimethyl-o-phenylenediamine | 94844-78-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-benzenesulfonyl-4,5-dimethyl-o-phenylenediamine
• 英文别名: 5-Amino-4-benzolsulfonylamino-1,2-dimethyl-benzol；N-(2-amino-4,5-dimethylphenyl)benzenesulfonamide
• CAS: 94844-78-7
• 化学式: C₁₄H₁₆N₂O₂S
• 分子量: 276.359
• InChiKey: TVZIFKHKLWIJFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  80.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  丁二酸酐 、 N-benzenesulfonyl-4,5-dimethyl-o-phenylenediamine 生成 Bernsteinsaeure-mono-<6-benzolsulfonylamino-3,4-dimethyl-anilid
  参考文献：
  名称：

  1,2-二甲基-4,5-二苯并苯分子的类固醇类似物的合成。

  摘要：

  DOI：

  10.1021/jm00341a030
• 作为产物：
  描述：

  4，5-二甲基-1，2-苯二胺 、 苯磺酰氯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 生成 N-benzenesulfonyl-4,5-dimethyl-o-phenylenediamine
  参考文献：
  名称：

  Novel N-coordinate half-sandwich ruthenium(II) arene complexes bearing sulfonamide fragments: Catalytic activities in the TH of acetophenone derivatives

  摘要：

  The novel cationic N-coordinate ruthenium(II)/arene complexes (6-10) were prepared from the starting complex [RuCl2(p-cymene)](2) dimer. The structures of the [(p-cymene)RuLCl]Cl (L = N-arenesulfonyl-4,5-dimethyl-o-phenylenediamines) complexes were elucidated by FT-IR, H-1-NMR,C-13-NMR, ionic conductivity techniques, and elemental analysis methods. The 6-10 complexes were applied as catalyst in the transfer hydrogenation (TH) of ketones. The catalytic tests showed that all the complexes are moderate catalysis precursors. Especially, {[N-benzenesulfonyl-4,5-dimethyl-o-phenylenediamine]-(p-cymene)-di-chloro-ruthenium(II)} (8) and {[N-4-chlorobenzenesulfonyl-4,5-dimethyl-o-phenylenediamine]-(p-cymene)-di-chloro-ruthenium(II)} (9) compounds were found to be a good catalysts in comparison to the others giving the corresponding alcohols in a good turnover frequency value of 1534 and 1731 h(-1), respectively. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2015.06.082

文献信息

• Novel N-coordinate half-sandwich ruthenium(II) arene complexes bearing sulfonamide fragments: Catalytic activities in the TH of acetophenone derivatives
  作者：Nilgün Kayaci、Serkan Dayan、Nilgun Kalaycioglu Ozpozan

  DOI：10.1016/j.molstruc.2015.06.082

  日期：2015.11

  The novel cationic N-coordinate ruthenium(II)/arene complexes (6-10) were prepared from the starting complex [RuCl2(p-cymene)](2) dimer. The structures of the [(p-cymene)RuLCl]Cl (L = N-arenesulfonyl-4,5-dimethyl-o-phenylenediamines) complexes were elucidated by FT-IR, H-1-NMR,C-13-NMR, ionic conductivity techniques, and elemental analysis methods. The 6-10 complexes were applied as catalyst in the transfer hydrogenation (TH) of ketones. The catalytic tests showed that all the complexes are moderate catalysis precursors. Especially, [N-benzenesulfonyl-4,5-dimethyl-o-phenylenediamine]-(p-cymene)-di-chloro-ruthenium(II)} (8) and [N-4-chlorobenzenesulfonyl-4,5-dimethyl-o-phenylenediamine]-(p-cymene)-di-chloro-ruthenium(II)} (9) compounds were found to be a good catalysts in comparison to the others giving the corresponding alcohols in a good turnover frequency value of 1534 and 1731 h(-1), respectively. (C) 2015 Elsevier B.V. All rights reserved.
• Synthesis of Oncolytic Analogs of 1,2-Dimethyl-4,5-diaminobenzene
  作者：D. W. Woolley、John Morrow Stewart

  DOI：10.1021/jm00341a030

  日期：1963.9