ethyl 1-diphenylphosphinoylcyclopentanecarboxylate | 131303-92-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl 1-diphenylphosphinoylcyclopentanecarboxylate
• 英文别名: Ethyl 1-diphenylphosphorylcyclopentane-1-carboxylate
• CAS: 131303-92-9
• 化学式: C₂₀H₂₃O₃P
• 分子量: 342.375
• InChiKey: MJNQQHHNLCAPOM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ethyl 1-diphenylphosphinoylcyclopentanecarboxylate 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 反应 24.0h， 以32%的产率得到1-(Diphenyl-phosphinoyl)-cyclopentanecarboxylic acid
  参考文献：
  名称：

  Cycloalkylation of compounds in the series of phosphorus-substituted derivatives of acetic acid

  摘要：

  1-Phosphoryl-substituted cyclopropanes, cyclobutanes, and cyclopentanes were obtained by the reaction of phosphoryl-substituted esters and nitriles of acetic acid with alpha,omega-dihaloalkanes. The influence of the CH-acidity of the starting compounds and electrophilicity of the alkylating agent on the reaction rate was examined.

  DOI：

  10.1007/bf00961505
• 作为产物：
  描述：

  1,4-二溴丁烷 、 乙基(二苯基磷酰)乙酸酯 在 caesium carbonate 作用下， 以 四氢呋喃 为溶剂， 反应 15.0h， 以92%的产率得到ethyl 1-diphenylphosphinoylcyclopentanecarboxylate
  参考文献：
  名称：

  Yarkevich, A. N.; Tsvetkov, E. N., Russian Journal of General Chemistry, 1994, vol. 64, # 10.1, p. 1451 - 1455

  摘要：

  DOI：

文献信息

• Cycloalkylation of compounds in the series of phosphorus-substituted derivatives of acetic acid
  作者：P. V. Kazakov、I. L. Odinets、A. P. Laretina、T. M. Shcherbina、P. V. Petrovskii、L. V. Kovalenko、T. A. Mastryukova

  DOI：10.1007/bf00961505

  日期：1990.8

  1-Phosphoryl-substituted cyclopropanes, cyclobutanes, and cyclopentanes were obtained by the reaction of phosphoryl-substituted esters and nitriles of acetic acid with alpha,omega-dihaloalkanes. The influence of the CH-acidity of the starting compounds and electrophilicity of the alkylating agent on the reaction rate was examined.
• KAZAKOV, P. V.;ODINETS, I. L.;LARETINA, A. P.;SHCHERBINA, T. M.;PETROVSKI+, IZV. AN CCCP. CEP. XIM.,(1990) N, S. 1873-1880
  作者：KAZAKOV, P. V.、ODINETS, I. L.、LARETINA, A. P.、SHCHERBINA, T. M.、PETROVSKI+

  DOI：——

  日期：——
• Jarkewitsch A. N., Chwetkow E. N., Zh. obshh. khimii, 64 (1994) N 10, S 1629-1633
  作者：Jarkewitsch A. N., Chwetkow E. N.

  DOI：——

  日期：——
• Yarkevich, A. N.; Tsvetkov, E. N., Russian Journal of General Chemistry, 1994, vol. 64, # 10.1, p. 1451 - 1455
  作者：Yarkevich, A. N.、Tsvetkov, E. N.

  DOI：——

  日期：——
• Turanov; Karandashev; Yarkevich, Russian Journal of General Chemistry, 1999, vol. 69, # 7, p. 1061 - 1067
  作者：Turanov、Karandashev、Yarkevich、Orlova、Kharitonov、Tsvetkov

  DOI：——

  日期：——