2-Ethylbutyl butyrate | 74398-53-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Ethylbutyl butyrate
• 英文别名: 2-ethylbutyl butanoate
• CAS: 74398-53-1
• 化学式: C₁₀H₂₀O₂
• mdl: MFCD06252419
• 分子量: 172.26
• InChiKey: ORLMWYKVMXNKNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER<br/>[FR] DÉRIVÉS DE LA MÉTHYLAMINE COMME INHIBITEURS DE LA LYSYL OXIDASE POUR LE TRAITEMENT DU CANCER
  申请人：THE INST OF CANCER RESEARCH: ROYAL CANCER HOSPITAL

  公开号：WO2017141049A1

  公开（公告）日：2017-08-24

  Provided are compounds of the Formula (I), or a pharmaceutically acceptable salt thereof, wherein W, X, Y, Z, x, R1, R2, R3, x and n are defined in the specification. The compounds are inhibitors of lysyl oxidase (LOX) and lysyl oxidase-like (LOXL) family members (LOXL1, LOXL2, LOXL3, LOXL4) and are useful in therapy, particularly in the treatment of cancer. Also disclosed are LOX inhibitors for use in the treatment of a cancer associated with EGFR and biomarkers that predict responsiveness to a LOX inhibitor.

  提供的是Formula (I)的化合物，或其药用可接受的盐，其中W、X、Y、Z、x、R1、R2、R3、x和n在规范中有定义。这些化合物是赖氨酸氧化酶（LOX）和赖氨酸氧化酶样（LOXL）家族成员（LOXL1、LOXL2、LOXL3、LOXL4）的抑制剂，并且在治疗中很有用，特别是在癌症治疗中。还披露了用于治疗与EGFR相关的癌症的LOX抑制剂，以及预测对LOX抑制剂响应性的生物标志物。
• ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER
  申请人：INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY

  公开号：US20190031586A1

  公开（公告）日：2019-01-31

  An organic compound, a three-dimensional organic structure formed by using the organic compound, a separation sieve and an optical layer having the organic structure, and an optical device having the optical layer as an optical amplification layer are provided. The organic structure includes a plurality of organic molecules self-assembled by non-covalent bonding. Each of the unit organic molecules has an aromatic ring, a first pair of substituents being connected to immediately adjacent positions of substitutable positions of the aromatic ring, and a second pair of substituents being connected to immediately adjacent positions of remaining substitutable positions of the aromatic ring. The unit organic molecules are self-assembled by van der Waals interaction, London dispersion interaction or hydrogen bonding between the first and the second pairs of the substituents and by pi-pi interactions between the aromatic rings.

  提供一种有机化合物，通过使用该有机化合物形成的三维有机结构、分离筛和具有该有机结构的光学层，以及具有光学层作为光学放大层的光学器件。该有机结构包括通过非共价键自组装的多个有机分子。每个单元有机分子具有芳香环，第一对取代基连接到芳香环的可取代位置的相邻位置，第二对取代基连接到芳香环的剩余可取代位置的相邻位置。单元有机分子通过范德华力相互作用、伦敦分散相互作用或氢键作用于第一和第二对取代基之间的π-π相互作用而自组装。
• CHARGE-TRANSPORTING VARNISH
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP3109914A1

  公开（公告）日：2016-12-28

  A charge-transporting varnish which contains a charge-transporting substance and an organic solvent, and which is characterized in that the organic solvent contains an acid amide derivative represented by formula (A) as a good solvent. (In the formula, R0 represents a propyl group or an isopropyl group; and each of RA and RB independently represents an alkyl group having 1-4 carbon atoms.)

  一种电荷传输清漆，它含有一种电荷传输物质和一种有机溶剂，其特征在于有机溶剂含有一种由式（A）代表的酸酰胺衍生物作为良好溶剂。 (式中，R0 代表丙基或异丙基；RA 和 RB 各自独立地代表具有 1-4 个碳原子的烷基)。
• CHARGE-TRANSPORTING VARNISH, CHARGE-TRANSPORTING FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP3249710A1

  公开（公告）日：2017-11-29

  Provided is a charge-transporting varnish that includes: a charge-transporting material comprising an arylamine derivative represented by formula (1); a dopant; and an organic solvent.

  本发明提供了一种电荷传输清漆，它包括：一种电荷传输材料，其中包含由式（1）表示的芳基胺衍生物；一种掺杂剂；以及一种有机溶剂。
• VARNISH FOR FORMATION OF CHARGE-TRANSPORTING THIN FILM
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP3252840A1

  公开（公告）日：2017-12-06

  Provided is a varnish for the formation of a charge-transporting thin film, said varnish including an organic solvent, a charge-transporting substance, and a 2,2,6,6-tetraalkylpiperidine-N-oxyl derivative represented by formula (T1) (in the formula, each RA independently represents a C1-20 alkyl group, and RB represents a hydrogen atom, a hydroxy group, an amino group, a carboxyl group, a cyano group, an oxo group, an isocyanato group, a C1-20 alkoxy group, a C2-20 alkylcarbonyloxy group, a C7-20 arylcarbonyloxy group, a C2-20 alkylcarbonylamino group or a C7-20 arylcarbonylamino group).

  本发明提供了一种用于形成电荷传输薄膜的清漆，所述清漆包括有机溶剂、电荷传输物质和由式 (T1) 表示的 2，2，6，6-四烷基哌啶-N-氧代衍生物 (式中，每个 RA 独立地代表一个 C1-20 烷基，RB 代表一个氢原子、一个羟基、一个氨基、一个羧基、一个氰基、一个氧代基、一个异氰基、一个 C1-20 烷氧基、一个 C2-20 烷基羰氧基、一个 C7-20 芳基羰氧基、一个 C2-20 烷基羰基氨基或一个 C7-20 芳基羰基氨基）。

表征谱图