N-[2-(1H-咪唑-4-基)乙基]-1H-腺嘌呤 | 1669-86-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 中文名称: N-[2-(1H-咪唑-4-基)乙基]-1H-腺嘌呤
• 中文别名: 1H-嘌呤-6-胺,N-[2-(1H-咪唑基-4-基)乙基]-；N-(2-(1H-咪唑基-4-基)乙基)-1H-腺嘌呤；N-(2-(1H-咪唑基-5-基)乙基)-9H-嘌呤-6-胺；N-(2-(1H-咪唑基-4-基)乙基)-9H-嘌呤-6-胺；N-[2-(3H-咪唑基-4-基)乙基]-7H-嘌呤-6-胺；2-(3H-咪唑基-4-基)乙基-(7H-嘌呤-6-基)胺
• 英文名称: [2-(1(3)H-imidazol-4-yl)-ethyl]-(7(9)H-purin-6-yl)-amine
• 英文别名: [2-(1(3)H-Imidazol-4-yl)-aethyl]-(7(9)H-purin-6-yl)-amin；N-[2-(1H-imidazol-4-yl)ethyl]-1H-adenine；N-[2-(1H-imidazol-5-yl)ethyl]-9H-purin-6-amine；N-[2-(1H-imidazol-5-yl)ethyl]-7H-purin-6-amine
• CAS: 1669-86-9
• 化学式: C₁₀H₁₁N₇
• mdl: MFCD22374939
• 分子量: 229.244
• InChiKey: SOTQBOWAIHEECH-UHFFFAOYSA-N

物化性质

• 熔点：
  256-257 °C(Solv: water (7732-18-5))
• 沸点：
  514.6±60.0 °C(Predicted)
• 密度：
  1.62±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  95.2
• 氢给体数：
  3
• 氢受体数：
  5

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  6-甲巯基嘌呤 、 组胺 在 水 作用下， 生成 N-[2-(1H-咪唑-4-基)乙基]-1H-腺嘌呤
  参考文献：
  名称：

  Effects of Some 6-(Substituted)-purines on Regeneration of Hydra

  摘要：

  DOI：

  10.1021/ja01600a075

文献信息

• Immobilized nuckeic acids and uses thereof
  申请人：Burmeister Jens

  公开号：US20050208487A1

  公开（公告）日：2005-09-22

  One aspect of the present invention relates to an immobilized nucleic acid comprising a nucleic acid and a matrix where the nucleic acid is a Spiegelmer and the Spiegelmer is functionally active. Another aspect of the invention concerns an immobilized nucleic acid comprising a nucleic acid and a matrix where the nucleic acid is coupled to the matrix at least via its 3′ end and the nucleic acid is a functional nucleic acid. Finally a further aspect of the invention concerns the use of such immobilized nucleic acids as affinity ligands for example in chromatography and in apheresis.

  本发明的一个方面涉及一种固定化核酸，包括核酸和基质，其中核酸是明镜聚合物，明镜聚合物具有功能活性。本发明的另一方面涉及一种固定化核酸，包括核酸和基质，其中核酸至少通过其 3′端与基质耦合，核酸是一种功能性核酸。最后，本发明的另一个方面涉及将这种固定化核酸用作亲和配体，例如在色谱法和无细胞疗法中使用。
• OLIGONUCLEOTIDE LINKER AND TECHNIQUES INVOLVING IMMOBILIZED AND LINKED OLIGONUCLEOTIDES
  申请人：PRESIDENT AND FELLOWS OF HARVARD COLLEGE

  公开号：EP0917533A2

  公开（公告）日：1999-05-26
• PURIFICATION OF OLIGOMERS USING DUAL-END SELECTION
  申请人：Bayer Corporation

  公开号：EP1105404B1

  公开（公告）日：2003-10-29
• NUCLEIC ACID AMPLIFICATION METHOD
  申请人：Keygene N.V.

  公开号：EP3807420A1

  公开（公告）日：2021-04-21
• Coherent electron junction scanning probe interference microscope, nanomanipulator and spectrometer with assembler and DNA sequencing applications
  申请人：Zorn Delmar Miguel

  公开号：US20070194225A1

  公开（公告）日：2007-08-23

  The present invention is directed toward the fabrication and operation of a coherent electron quantum interferometer for scanning probe microscopy. The device may also be operated in a mode where single electrons are used in the sample probe. The device may operate in modes where scanning probe behavior, Kondo effect and/or Aharanov-Bohm interferometer behavior can be observed. The use of nucleic acid molecules attached to the probe structures allows for interrogation of RNA and DNA molecules absorbed on the sample substrate and potentially the sequencing of genetic material using coherent spectroscopic electron imaging in conjunction with prior art probe methods. An embodiment with genetic algorithm generated molecular arrays and circuit prototyping areas is provided in a preferred embodiment for an evolvable hardware embodiment of a coherent electron interferometer nanomanipulator platform. Nanotweezers with Raman optical and mass spectroscopic means are provided in a preferred embodiment for assembly, characterization and nanomanipulation.